Patents by Inventor Hazel Sive

Hazel Sive has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Increasing RNAi efficiency through single nucleotide mismatches
    Patent number: 11208653
    Abstract: Methods and compositions for increasing RNAi efficiency through single nucleotide mismatches.
    Type: Grant
    Filed: April 27, 2017
    Date of Patent: December 28, 2021
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Grace Chen, David Bartel, Hazel Sive
  • INCREASING RNAi EFFICIENCY THROUGH SINGLE NUCLEOTIDE MISMATCHES
    Publication number: 20210130819
    Abstract: Methods and compositions for increasing RNAi efficiency through single nucleotide mismatches.
    Type: Application
    Filed: April 27, 2017
    Publication date: May 6, 2021
    Inventors: Grace Chen, David Bartel, Hazel Sive
  • Frazzled nucleotide sequences and expression products
    Patent number: 6165748
    Abstract: Purified Frazzled proteins, including WG67-16, WG67-19 and WA628, and processes for producing them are disclosed. DNA molecules encoding the Frazzled proteins, including WG67-16, WG67-19 and WA628, are also disclosed. The proteins may be used in modulating the binding of Wnt genes to their receptor. They are useful in the modulation of cellular formation, growth, differentiation, proliferation and/or maintenance of a variety of adult and embryonic tissues and organs.
    Type: Grant
    Filed: July 11, 1997
    Date of Patent: December 26, 2000
    Assignees: Genetics Institute, Inc., Whitehead Institute for Biomedical Research
    Inventors: Lisa Racie, Edward Lavallie, Janet Paulsen, Hazel Sive, Benjamin Sun