Patents by Inventor He Cheng

He Cheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260158255
    Abstract: A method includes illuminating a medium with optical illumination. The medium is optically curable to form a cured structure of a portion of the medium that is illuminated by a concentration of the optical illumination. The optical illumination is incident on the medium along an optical axis. Illuminating includes forming illumination that is both axially and transversely structured to form a volumetric structure in the medium that is contoured relative to the optical axis.
    Type: Application
    Filed: November 7, 2025
    Publication date: June 11, 2026
    Applicant: University of Central Florida Research Foundation, Inc.
    Inventors: Alexander Cockerham, Stephen M. Kuebler, Xiaoming Yu, He Cheng
  • Patent number: 12325881
    Abstract: This technology relates to a method of treating breast cancer in a subject and a method of determining whether a breast lesion in a subject is malignant or benign using miRNA panels.
    Type: Grant
    Filed: April 4, 2022
    Date of Patent: June 10, 2025
    Assignees: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH, Singapore Health Services Pte Ltd, National University Hospital (Singapore) Pte Ltd, Tan Tock Seng Hospital Pte Ltd, Mirxes Lab Pte Ltd
    Inventors: Siew Gek Lee-Lim, Ruiyang Zou, Lihan Zhou, He Cheng, Bo Anders Mikael Hartman, Heng-Phon Too
  • Publication number: 20240352530
    Abstract: Disclosed herein is a method for determining whether a subject is suffering from, or is at risk of developing breast cancer, wherein the method comprises detecting differential expression levels of at least two or more miRNA markers from a biological sample. Also disclosed herein is a method of determining whether a subject is suffering from, or is at risk of developing, breast cancer based on miRNA expression.
    Type: Application
    Filed: August 2, 2022
    Publication date: October 24, 2024
    Applicants: National University of Singapore, Singapore Health Services Pte. Ltd., MiRXES Lab Pte. Ltd., National University Hospital (Singapore) Pte. Ltd.
    Inventors: Mikael Hartman BO ANDERS, Heng-Phon TOO, Siew Gek Ann LEE-LIM, Ruiyang ZOU, Lihan ZHOU, He CHENG
  • Publication number: 20230313308
    Abstract: This technology relates to a method of treating breast cancer in a subject and a method of determining whether a breast lesion in a subject is malignant or benign using miRNA panels.
    Type: Application
    Filed: April 4, 2022
    Publication date: October 5, 2023
    Inventors: Siew Gek Lee-Lim, Ruiyang Zou, Lihan Zhou, He Cheng, Bo Anders Mikael Hartman, Heng-Phon Too
  • Publication number: 20230287504
    Abstract: Provided are peripheral blood miRNA markers for diagnosis of non-small cell lung cancer, wherein the peripheral blood miRNA markers comprise hsa-miR-1291, hsa-miR-1-3p, hsa-miR-214-3p, hsa-miR-375 or hsa-let-7a-5p. Five specific diagnostic markers suitable for diagnosing non-small cell lung cancer in Asian and Caucasian populations are validated on a large number of samples, and have higher population specificity compared to other miRNA markers previously reported. These five miRNA diagnostic markers are proposed for the first time and are shown to be more reliable than other miRNA molecular markers.
    Type: Application
    Filed: November 11, 2019
    Publication date: September 14, 2023
    Inventors: Ruiyang Zou, Dan Su, He Cheng, Lisha Ying, Lihan Zhou
  • Patent number: 11543692
    Abstract: A high laser damage threshold reflective optically addressed liquid crystal spatial light modulator for shaping 1053 nm linearly polarized light beams, comprising a computer-controlled LCoS electrical addressable spatial light modulator, polarization beam splitter, and polarizer, Liquid crystal cell, analyzer, AC power supply, where the liquid crystal cell comprises a transparent conductive film antireflection film layer, a transparent conductive film base layer, a first transparent conductive layer, a liquid crystal alignment layer, a liquid crystal layer, an alignment element, a reflective film layer, a light guide layer, and a second transparent conductive layer. By changing the transparent conductive layer material of the light-transmitting part of the liquid crystal cell from ITO to gallium nitride material, the damage threshold of the high-energy laser is improved, which facilitates application of beam shaping in high-power laser devices.
    Type: Grant
    Filed: December 11, 2020
    Date of Patent: January 3, 2023
    Assignee: Shanghai Institute of Optics And Fine Mechanics, Chinese Academy of Sciences
    Inventors: Wei Fan, Zhibo Xing, Dajie Huang, He Cheng, Gang Xia
  • Publication number: 20210356800
    Abstract: A high laser damage threshold reflective optically addressed liquid crystal spatial light modulator for shaping 1053 nm linearly polarized light beams, comprising a computer-controlled LCoS electrical addressable spatial light modulator, polarization beam splitter, and polarizer, Liquid crystal cell, analyzer, AC power supply, where the liquid crystal cell comprises a transparent conductive film antireflection film layer, a transparent conductive film base layer, a first transparent conductive layer, a liquid crystal alignment layer, a liquid crystal layer, an alignment element, a reflective film layer, a light guide layer, and a second transparent conductive layer. By changing the transparent conductive layer material of the light-transmitting part of the liquid crystal cell from ITO to gallium nitride material, the damage threshold of the high-energy laser is improved, which facilitates application of beam shaping in high-power laser devices.
    Type: Application
    Filed: December 11, 2020
    Publication date: November 18, 2021
    Inventors: Wei FAN, Zhibo XING, Dajie HUANG, He CHENG, Gang XIA
  • Patent number: 9979342
    Abstract: A switch reluctance motor wide speed-regulation range cross-control method, the switch reluctance motor wide speed-regulation range control system consisting of a revolving speed regulator, a current chopper controller, an angle position controller, a chopper counter, a comparison selector and two resettable constant registers; the chopper counter counts the current chopping number of each electrical period, and according to the comparison result between a counting value of the chopper counter and a constant value set by the two constant registers, the comparison selector selects the current chopper controller or the angle position controller, such that when in the three phases of low revolving speed, medium revolving speed and high revolving speed or in the runtime of acceleration, deceleration and uniform velocity, the current chopper controller and the angle position controller can automatically switch, and seamlessly connect without being affected by load change, and switching from a turn-on angle to a tu
    Type: Grant
    Filed: October 16, 2015
    Date of Patent: May 22, 2018
    Assignee: CHINA UNIVERSITY OF MINING AND TECHNOLOGY
    Inventors: Hao Chen, He Cheng, Zhou Yang, Qing Wang, Qianlong Wang, Weilong Huang
  • Patent number: 9923496
    Abstract: A fault-tolerant control method for a position sensor of a switched reluctance motor, if the position sensor of the switched reluctance motor runs without a fault, detecting, in real time, four equal-interval or equal-angle continuous edge pulses of an output signal of the position sensor, the fourth edge pulse being the current edge pulse, and detecting time intervals (T1, T2, T3) between each two adjacent edge pulses sequentially, thereby calculating a time interval (T4) between the current edge pulse and a next edge pulse following the current edge pulse. If the position sensor of the switched reluctance motor fails, and the next edge pulse following the current edge pulse is lost, reconstructing the next edge pulse after the interval time (T4) of the current edge pulse of the output signal of the position sensor.
    Type: Grant
    Filed: August 20, 2015
    Date of Patent: March 20, 2018
    Assignee: China University of Mining and Technology
    Inventors: Hao Chen, Guoqiang Han, He Cheng, Qianlong Wang, Qing Wang, Xing Wang
  • Patent number: 9871476
    Abstract: A braking torque closed-loop control system and method for a switch reluctance motor. The closed-loop control system comprises a torque regulator, a mode selector, a current regulator, an angle optimization controller and a torque estimator. On the basis of the rotating speed of the motor, the mode selector implements a phase current soft chopper control in a low rotating speed region and an angle position control in a high rotating speed region. The current regulator performs soft chopper hysteretic current regulation. The angle optimization controller optimizes a turn-on angle and a turn-off angle of a power converter master switch to reduce torque pulsation and improve braking energy feedback efficiency. The torque estimator conducts an on-line estimation of an actual braking torque estimated value of the motor based on an actual phase voltage and current of the motor to achieve braking torque signal feedback.
    Type: Grant
    Filed: November 30, 2015
    Date of Patent: January 16, 2018
    Assignee: CHINA UNIVERSITY OF MINING AND TECHNOLOGY
    Inventors: Hao Chen, He Cheng, Zhou Yang, Qing Wang, Qianlong Wang, Xing Wang
  • Publication number: 20170324358
    Abstract: A fault-tolerant control method for a position sensor of a switched reluctance motor, if the position sensor of the switched reluctance motor runs without a fault, detecting, in real time, four equal-interval or equal-angle continuous edge pulses of an output signal of the position sensor, the fourth edge pulse being the current edge pulse, and detecting time intervals (T1, T2, T3) between each two adjacent edge pulses sequentially, thereby calculating a time interval (T4) between the current edge pulse and a next edge pulse following the current edge pulse. If the position sensor of the switched reluctance motor fails, and the next edge pulse following the current edge pulse is lost, reconstructing the next edge pulse after the interval time (T4) of the current edge pulse of the output signal of the position sensor.
    Type: Application
    Filed: August 20, 2015
    Publication date: November 9, 2017
    Inventors: Hao CHEN, Guoqiang HAN, He CHENG, Qianlong WANG, Qing WANG, Xing WANG
  • Publication number: 20170250635
    Abstract: A braking torque closed-loop control system and method for a switch reluctance motor. The closed-loop control system comprises a torque regulator, a mode selector, a current regulator, an angle optimization controller and a torque estimator. On the basis of the rotating speed of the motor, the mode selector implements a phase current soft chopper control in a low rotating speed region and an angle position control in a high rotating speed region. The current regulator performs soft chopper hysteretic current regulation. The angle optimization controller optimizes a turn-on angle and a turn-off angle of a power converter master switch to reduce torque pulsation and improve braking energy feedback efficiency. The torque estimator conducts an on-line estimation of an actual braking torque estimated value of the motor based on an actual phase voltage and current of the motor to achieve braking torque signal feedback.
    Type: Application
    Filed: November 30, 2015
    Publication date: August 31, 2017
    Inventors: Hao CHEN, He CHENG, Zhou YANG, Qing WANG, Qianlong WANG, Xing WANG
  • Publication number: 20170187314
    Abstract: A switch reluctance motor wide speed-regulation range cross-control method, the switch reluctance motor wide speed-regulation range control system consisting of a revolving speed regulator, a current chopper controller, an angle position controller, a chopper counter, a comparison selector and two resettable constant registers; the chopper counter counts the current chopping number of each electrical period, and according to the comparison result between a counting value of the chopper counter and a constant value set by the two constant registers, the comparison selector selects the current chopper controller or the angle positon controller, such that when in the three phases of low revolving speed, medium revolving speed and high revolving speed or in the runtime of acceleration, deceleration and uniform velocity, the current chopper controller and the angle positon controller can automatically switch, and seamlessly connect without being affected by load change, and switching from a turn-on angle to a turn
    Type: Application
    Filed: October 16, 2015
    Publication date: June 29, 2017
    Inventors: Hao CHEN, He CHENG, Zhou YANG, Qing WANG, Qianlong WANG, Weilong HUANG
  • Publication number: 20140357529
    Abstract: There is provided a microarray comprising a plurality of active agents immobilized onto an array of porous nanostructures, wherein each nanostructure has a network of pores that extends throughout the thickness of said nano structure.
    Type: Application
    Filed: December 19, 2012
    Publication date: December 4, 2014
    Applicant: National University of Singapore
    Inventors: Wee Kiong Choi, Heng Phon Too, Raj Rajagopalan, Lihan Zhou, Mohammed Khalid Bin Dawood, Han Zheng, He Cheng