Abstract: The present application relates to a bi-functional therapeutic for treating cancer that includes a targeting component which targets a tumor-associated antigen and an enzyme which, when delivered to a tumor by said targeting component, converts the tumor phenotype to that of an incompatible allograft or xenograft. The enzyme is coupled to the targeting component. Also disclosed is a method for treating cancer comprising administering the bi-functional therapeutic.

Abstract: The present invention discloses a bladder cancer detection kit and detection method. The kit includes a DHFR PCR reaction solution, a Twist1 and TSC21 PCR reaction solution, a point mutation positive control, a methylation positive control and a negative control. According to the present invention, by detecting the point mutation of a DHFR gene and the methylation level of a promoter region of TSC21 and Twist1 genes in a sample, the joint detection of gene point mutation and methylation is achieved for determining whether the sample is cancerous. The kit is convenient and simple to operate, high in detection sensitivity and high in specificity, and has a very positive significance in the detection of bladder cancer.

Abstract: A transparent antenna and a communication system are provided and belong to the field of communication technology. The transparent antenna includes: a dielectric layer including opposite first and second surfaces in a thickness direction thereof; a first conductive layer on the first surface of the dielectric layer and including at least one first feed line and at least one second feed line; and a second conductive layer on the second surface of the dielectric layer and including at least one first opening; an outline of an orthographic projection of each first opening on the dielectric layer intersects with an orthographic projection of each of corresponding first and second feed lines on the dielectric layer, which extends into the orthographic projection of the first opening on the dielectric layer, and the at least one first feed line and the at least one second feed line have different feeding directions.

Abstract: The embodiment of the present disclosure provides a memory controller, device, system, and method. The memory controller includes an interface and a processor, wherein the processor is configured to: obtain a statistical result of a physical page corresponding to a first read voltage, wherein the statistical result includes at least one of a first number of bits flipped in two read results of the physical page corresponding to the first read voltage and a read voltage whose voltage difference with the first read voltage is less than a preset voltage, or a second number of bits of the physical page not successfully read using the first read voltage; the first read voltage is less than a mean value of a threshold voltage interval corresponding to an intermediate storage state of the physical page; and determine a read disturb state of the physical page according to the statistical result.

Abstract: Memory controllers, devices, systems, operating methods thereof, and storage media are provided. In one aspect, a memory controller includes a processor configured to: obtains a statistical result of a physical page corresponding to a first read voltage. The statistical result includes at least one of a first number of bits flipped between two read results of the physical page corresponding to the first read voltage and a read voltage having a voltage difference of less than a preset voltage with the first read voltage, or a second number of bits of the physical page successfully read using the first read voltage. The first read voltage is greater than a mean value of a threshold voltage interval corresponding to an intermediate storage state of the physical page. The process is further configured to determine a data retention state of the physical page according to the statistical result.

Abstract: An audio power amplifier circuit and a duty cycle modulation circuit and a noise suppression circuit thereof are disclosed. The audio power amplification circuit includes an integral amplifier module and a high frequency switch The duty cycle modulation circuit is used to adjusts a gain of the audio power amplifier circuit by controlling a duty cycle of the high frequency switch. The duty cycle modulation circuit counts pulses of a duty cycle modulation signal to obtain a first count value counts pulses of a clock signal to obtain a second counting value and performs a logical operation according to the first count value, the second count value, and the clock signal to obtain a switch modulation signal for controlling the high frequency switch. The “pop” noise is weakened by controlling the gain of the audio power amplifier circuit, and the cost is reduced while meeting the high linearity of the circuit.

Abstract: An antenna includes a first substrate and a second substrate oppositely arranged; the first substrate includes: a first dielectric substrate having a first surface and a second surface oppositely arranged; a reference electrode layer on the first surface; at least one first radiation part on the second surface and having an orthographic projection on the first dielectric substrate at least partially overlapping that of the reference electrode layer; and at least one feeding structure on the second surface, electrically connected to the first radiation part, and having an orthographic projection on the first dielectric substrate at least partially overlapping that of the reference electrode layer; the second substrate includes: a second dielectric substrate opposite to the second surface; and at least one second radiation part on the second dielectric substrate, and each having an orthographic projection on the first surface within that of one first radiation part.

Abstract: A display substrate is provided, including: a base substrate; a first conductive layer, a second conductive layer, a semiconductor layer, a third conductive layer and a passivation layer sequentially arranged on the base substrate along a direction away from the base substrate; and a first electrode via hole penetrating the passivation layer. The second conductive layer, includes a first electrode. The second conductive layer includes a gate electrode. The third conductive layer includes a transfer portion, of which an orthographic projection on the base substrate falls within an orthographic projection of the first electrode on the base. An opening area of the first electrode via hole gradually decreases in a direction pointing towards the base substrate, and an exposed part of the transfer portion by the first electrode via hole serves as a part of a via hole sidewall of the first electrode via hole.

Abstract: The present application relates to a bi-functional therapeutic for treating cancer that includes a targeting component which targets a tumor-associated antigen and an enzyme which, when delivered to a tumor by said targeting component, converts the tumor phenotype to that of an incompatible allograft or xenograft. The enzyme is coupled to the targeting component. Also disclosed is a method for treating cancer comprising administering the bi-functional therapeutic.

Abstract: A vehicle frame and a vehicle are provided. The vehicle frame includes the vehicle frame includes a frame body and an antenna device, and the frame body includes a plurality of supporting beams fixedly connected and is further provided with a protection part; and the antenna device is mounted on the frame body, and the protection part is disposed outside the antenna device, to block the antenna device from an object in an external environment.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for video streaming. One of the methods includes obtaining a collection of one or more video files at a content delivery system; for each video file: determining a set of video ladders for the video file, each video ladder corresponding to a transcoding version of the video file having particular parameters, the set of video ladders determined based on a set of individual ladder values that substantially maximize a measure of utility for one or more users viewing a content the video, wherein the utility of the video is based at least in part on a complexity of the video content and historical network characteristics; for each ladder in the set of video ladders, transcoding the video file into a corresponding version; and storing each transcoded version of the video for delivery to user devices.

Abstract: The present disclosure provides a phase shifter, an antenna and an electronic device, and belongs to the field of communication technology. The phase shifter includes a plurality of phase shifting units, a first power division network and a second power division network; each phase shifting unit includes a first transmission structure and a second transmission structure; the first power division network includes a first feeding port and a plurality of second feeding ports; the second power division network includes a third feeding port and a plurality of fourth feeding ports; and the first transmission structure of the phase shifting unit is electrically connected to one second feeding port; the second transmission structure of the phase shifting unit is electrically connected to one fourth feeding port.

Abstract: An antenna includes a first substrate and a second substrate oppositely arranged; the first substrate includes: a first dielectric substrate having a first surface and a second surface oppositely arranged; a reference electrode layer on the first surface; at least one first radiation part on the second surface and having an orthographic projection on the first dielectric substrate at least partially overlapping that of the reference electrode layer; and at least one feeding structure on the second surface, electrically connected to the first radiation part, and having an orthographic projection on the first dielectric substrate at least partially overlapping that of the reference electrode layer; the second substrate includes: a second dielectric substrate opposite to the second surface; and at least one second radiation part on the second dielectric substrate, and each having an orthographic projection on the first surface within that of one first radiation part.

Abstract: A heating circuit includes: at least two power supply circuits; at least two heating modules; and a selection circuit, connected with the at least two power supply circuits and the at least two heating modules, and configured to select at least one of the at least two power supply circuits to be connected to each of the at least two heating modules. Selecting the at least one power supply circuit for one of the at least two power supply circuits does not affect selecting the at least one power supply circuit for another one of the at least two power supply circuits.

Abstract: The present application provides a design method for a control box of an engineering machinery, including: determining the mounting positions of at least two types of handles on a box body of the control box, and designing the control box based on the determined mounting positions of the at least two types of handles on the box body of the control box, so that the control box meets the mounting requirement of the at least two types of handles. On such basis, the universality and later expansibility of the control box is improved, and production costs are reduced.

Abstract: An intelligent question answering method includes: determining, based on received question information, a target object and a target attribute corresponding to the question information; obtaining an answer knowledge path and an external knowledge path of the target object other than the answer knowledge path from a pre-established knowledge graph based on the target object and the target attribute, the answer knowledge path including target context information for describing the target attribute, and the external knowledge path including external context information for describing another attribute; inputting the answer knowledge path and the external knowledge path into a trained neural network model to obtain a reply text, a training corpus of the neural network model during training including at least comment information of the target object; and outputting the reply text.

Abstract: The present invention discloses a preparation method and recycling method for degradable and recyclable paper plastics with water resistance and high-strength. By coating cyclic carbonate and amine compounds on paper, these compounds penetrate the paper's fiber structure, followed by curing treatment, resulting in a recyclable, degradable, and reprocessed paper plastic material with water resistance and high-strength. This method involves coating only cyclic carbonate and amines onto the paper, which, after heating, yields the paper plastic. The invention offers versatility, enhancing various paper types with improved mechanical properties, temperature resistance, water resistance, and solvent resistance while maintaining degradation capability. The paper plastic exhibits excellent self-healing, plasticity, degradation, and reprocessing properties. The process method is straightforward and user-friendly, making it suitable for industrial-scale production.

Abstract: Disclosed is a method for preparing a heterogeneous metal composite structure for medical implantation, including the steps of: step 1, preparing titanium alloy powder into a porous skeleton according to different printing strategies; step 2, filling magnesium after being melted into pores of the porous skeleton; and step 3, cooling a titanium-magnesium interpenetrating phase composite structure prepared in step 2 to room temperature, and covering a surface of the titanium-magnesium interpenetrating phase composite structure with a hydroxyapatite coating. In the present disclosure, a porous lattice dot-array structure of titanium alloy is used as a skeleton, and the skeleton pore is filled by pressureless infiltration of magnesium or hot isostatic pressure.

Abstract: The present disclosure provides a phase shifter, an antenna and an electronic device, and belongs to the field of communication technology. The phase shifter includes a plurality of phase shifting units, a first power division network and a second power division network; each phase shifting unit includes a first transmission structure and a second transmission structure; the first power division network includes a first feeding port and a plurality of second feeding ports; the second power division network includes a third feeding port and a plurality of fourth feeding ports; and the first transmission structure of the phase shifting unit is electrically connected to one second feeding port; the second transmission structure of the phase shifting unit is electrically connected to one fourth feeding port.