Abstract: The present invention relates to a modified adeno-associated virus (AAV) capsid polypeptide and a novel recombinant adeno-associated virus (rAAV) comprising the modified AAV capsid polypeptide for delivering the gene product for the therapy. The present invention also relates to a pharmaceutical composition comprising the rAAV of the present invention, and a method of treating a retinal disease comprising the administration of the rAAV or the pharmaceutical composition of the present invention to an eye of a subject in need thereof.

Abstract: The present invention provides a polynucleotide and vector, in particular AAV vector, encoding a nanobody against VEGF. The present invention also provides a method of treating a disease associated with VEGF, such as the overexpression of VEGF, e.g., Wet-AMD and DME comprising administering the vector by, e.g., intravitreal injection to provide stable expression of the nanobody in eyes.

Abstract: This application provides example terminal device localization methods and related devices. One example method includes obtaining, from a vector map, a first map point matching a first feature point in a current image frame shot by a terminal device. A second map point matching a second feature point in another image frame before the current image frame is obtained from the vector map. A pose in which the terminal device shoots the current image frame is adjusted based on a target function to obtain, as a localization result of the terminal device, a pose in which the terminal device shoots the current image frame and that is obtained after current adjustment. The target function includes a first matching error between the first feature point and the first map point and a second matching error between the second feature point and the second map point.

Abstract: The present disclosure provides a method and system for calculating water-land-forage-livestock balance in a family pasture by taking forage quality into account. The method takes a family pasture as a calculation unit and starts from a water circulation process, various types of groundwater recharges of the family pasture are calculated, and an available groundwater quantity is calculated by using an exploitable coefficient method, and undergoes water-land balance calculation with an irrigation water demand and a drinking water demand of people and livestock; and total digestible nutrients of various types of forage are used to convert each type of forage into standard hay for forage-livestock balance calculation, so as to determine a maximum supportable planting area of irrigated artificial grasslands and a maximum supportable quantity of livestock raised in the family pasture.

Abstract: The invention discloses an impedance spectrum in-situ measuring device for the dielectric constant of solid materials at high temperature and high pressure conditions. The device comprises a cube-shaped pyrophyllite, a cylindrical opening penetrates between one end face of the pyrophyllite and the other end face opposite to the end face; a heater formed by sleeving annular stainless steel sheets is arranged in the opening; a first plate-shaped platinum electrode and a second plate-shaped platinum electrode are arranged in the cavity of the innermost ring-shaped stainless steel sheet. The first plate-shaped platinum electrode is electrically connected with one end of the Solartron 1260 Impedance/Gainphase Analyzer through a first lead, and the second plate-shaped platinum electrode is electrically connected with the other end of the Solartron 1260 Impedance/Gainphase Analyzer through a second lead.

Abstract: The invention discloses an impedance spectrum in-situ measuring device for the dielectric constant of solid materials at high temperature and high pressure conditions. The device comprises a cube-shaped pyrophyllite, a cylindrical opening penetrates between one end face of the pyrophyllite and the other end face opposite to the end face; a heater formed by sleeving annular stainless steel sheets is arranged in the opening; a first plate-shaped platinum electrode and a second plate-shaped platinum electrode are arranged in the cavity of the innermost ring-shaped stainless steel sheet. The first plate-shaped platinum electrode is electrically connected with one end of the Solartron 1260 Impedance/Gainphase Analyzer through a first lead, and the second plate-shaped platinum electrode is electrically connected with the other end of the Solartron 1260 Impedance/Gainphase Analyzer through a second lead.

Abstract: The present disclosure provides a method, a device and a computer readable storage medium for food risk traceability information classification.

Abstract: The present disclosure provides a method, a device and a computer readable storage medium for food risk traceability information classification.

Abstract: The present disclosure provides a logistics node tracing method and apparatus for finding a trace node among logistics nodes in a logistics chain network corresponding to a logistics unit. The method includes: obtaining chain network information of a logistics chain network corresponding to a logistics unit, and determining a target analysis domain and confidence node(s) of the logistics unit according to the chain network information; determining fast node(s) according to the chain network information, the target analysis domain, and a timeliness level of each of the logistics nodes in the logistics chain network; determining a predicted logistics route corresponding to the logistics unit according to the chain network information, the target analysis domain, and the confidence node(s); and determining the trace node corresponding to the logistics unit according to the fast node(s) and the predicted logistics route.

Abstract: The present invention discloses RNAi constructs derived from a Fusarium chitin synthase gene Chs3b, which has a nucleotide sequence as shown by SEQ ID NO: 1. Five distinct RNAi vectors are constructed for 5 different segments of the Chs3b gene (named Chs3b-1, 2, 3, 4, and 5, respectively), and separately transformed into Fusarium. It is found that siRiNAs in the transformed Fusarium shows a significant inhibition in fungal growth, development, and pathogenicity. The expression of the RNAi vectors against Chs3b in plants may inhibit the infection of Fusarium and improve the resistance of the transgenic plants to Fusarium head blight.

Abstract: The present invention discloses RNAi constructs derived from a Fusarium chitin synthase gene Chs3b, which has a nucleotide sequence as shown by SEQ ID NO: 1. Five distinct RNAi vectors are constructed for 5 different segments of the Chs3b gene (named Chs3b-1, 2, 3, 4, and 5, respectively), and separately transformed into Fusarium. It is found that siRiNAs in the transformed Fusarium shows a significant inhibition in fungal growth, development, and pathogenicity. The expression of the RNAi vectors against Chs3b in plants may inhibit the infection of Fusarium and improve the resistance of the transgenic plants to Fusarium head blight.