Patents by Inventor He Ping

He Ping has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20050228190
    Abstract: Materials and methods for preparing (S)-(+)-3-(aminomethyl)-5-methyl-hexanoic acid and structurally related compounds via enantioselective hydrogenation of prochiral olefins are disclosed. The methods employ novel chiral catalysts, which include C1-symmetric bisphosphine ligands bound to transition metals.
    Type: Application
    Filed: March 11, 2005
    Publication date: October 13, 2005
    Inventors: Jian Bao, Vladimir Beylin, Derek Greene, Garrett Hoge, William Kissel, Mark Marlatt, Derek Pflum, He-Ping Wu
  • Patent number: 6207197
    Abstract: There is provided a drug delivery composition for the controlled release of an active agent in the stomach environment over a prolonged period of time, which comprises a microsphere comprising an active ingredient in the inner core of the microsphere and (i) a rate controlling layer of a water insoluble polymer and (ii) an outer layer of a bioadhesive agent in the form of a cationic polymer.
    Type: Grant
    Filed: November 18, 1999
    Date of Patent: March 27, 2001
    Assignee: West Pharmaceutical Services Drug Delivery & Clinical Research Centre Limited
    Inventors: Lisbeth Illum, He Ping
  • Patent number: 5891717
    Abstract: Disclosed are compositions and methods for inhibiting hexokinase enzymes in mammalian cells. Specifically provided are proteins that stimulate the production of trehalose-6-phosphate and their respective genes; hexokinase-specific ribozymes and genes encoding such constructs; and agents that competitively reduce hexokinase activity, e.g., by displacing hexokinase from mitochondria, and their respective genes. The latter group of agents includes inactive hexokinases and fragments thereof that retain mitochondrial binding functions and hexokinase-glucokinase chimeras that further substitute glucokinase activity for hexokinase activity. Mammalian cells including such hexokinase inhibitors, methods of making such cells and various in vitro and in vivo methods of using cells with reduced hexokinase activity are also described herein.
    Type: Grant
    Filed: January 19, 1996
    Date of Patent: April 6, 1999
    Assignees: Betagene, Inc., Board of Regents, The University of Texas System
    Inventors: Christopher B. Newgard, He-Ping Han, Thomas C. Becker, John E. Wilson
  • Patent number: 5854067
    Abstract: Disclosed are compositions and methods for inhibiting hexokinase enzymes in mammalian cells. Specifically provided are proteins that stimulate the production of trehalose-6-phosphate and their respective genes; hexokinase-specific ribozymes and genes encoding such constructs; and agents that competitively reduce hexokinase activity, e.g., by displacing hexokinase from mitochondria, and their respective genes. The latter group of agents includes inactive hexokinases and fragments thereof that retain mitochondrial binding functions and hexokinase-glucokinase chimeras that further substitute glucokinase activity for hexokinase activity. Mammalian cells including such hexokinase inhibitors, methods of making such cells and various in vitro and in vivo methods of using cells with reduced hexokinase activity are also described herein.
    Type: Grant
    Filed: January 19, 1996
    Date of Patent: December 29, 1998
    Assignees: Board of Regents, The University of texas System, Betagene, Inc.
    Inventors: Christopher B. Newgard, He-Ping Han, Karl D. Normington
  • Patent number: 5241625
    Abstract: A system for remotely observing and optionally controlling information, including text and graphical images, displayed on a computer from among both homogeneous and heterogeneous computers coupled in a network or via other transport media such as magnetic disks captures window system event messages during a recording process. Such messages are then translated into procedure calls during the imaging process on the destination platform.
    Type: Grant
    Filed: November 27, 1990
    Date of Patent: August 31, 1993
    Assignee: Farallon Computing, Inc.
    Inventors: Marc A. Epard, He Ping, Neal E. Trautman, Paul F. VanVleck