Abstract: A freeze-dried formulation and a preparation method and an application thereof are provided. Triterpenoid saponin has a mass percentage of 0.004-95% in the freeze-dried formulation, a binding agent has a mass percentage of 0.01-99% in the freeze-dried formulation; the freeze-dried formulation is freeze-dried by a primary prepared solution containing the triterpenoid saponin and the binding agent; when the triterpenoid saponin has a mass percentage of 0.001%-50% in the primary prepared solution, the binding agent has a mass percentage of 0.01%-50% in the primary prepared solution, and a mass of the triterpenoid saponin increases with an increase of a mass of the binding agent; and when the triterpenoid saponin has a mass percentage of 50%-95% in the primary prepared solution, the binding agent has a mass percentage of 0.01%-20% in the primary prepared solution, and the mass of triterpenoid saponin decreases with the increase of the mass of the binding agent.

Abstract: Provided are a modified fabric having a surface thereof coated with a medium composition, and a production method thereof. The modified fabric includes a base fabric and a medium composition coated on the base fabric, the medium composition includes a medium, or includes a medium and a medium solvent capable of dissolving or dispersing the medium. Moreover, a multi-layer modified fabric having a surface thereof coated with a medium composition and a production method thereof are provided. The modified fabric is applicable to the fields such as cosmetics, daily necessities, medicines, and medical apparatus. The modified fabric also has no additives, carries a long shelf life, has stable and undamaged functional ingredients, a low production cost, and wide market adaptability.

Abstract: A freeze-dried excipient and a preparation method thereof. The freeze-dried excipient only comprises an active ingredient and a binder, and does not comprise a support agent. The weight ratio of the active ingredient to the binder is 1:100 to 100:1. The binder is adhesives, cellulose ethers, modified starches, PVP, carbomer, PVA, hyaluronic acids, albumin, chitosan, dextran, agar, polyamino acid, glycan or a combination thereof.

Abstract: The present invention provides methods for preparing compositions in blister packages using complex aluminum substrate materials, wherein said complex aluminum substrate materials comprise an intermediate aluminum layer, and first and second outer layers, wherein the material of the first outer layer differs from that of the second outer layer, and the flexural rigidity of the first outer layer differs from that of the second outer layer by 0-30%.

Abstract: An orally disintegrating formulation and its preparation are provided. The orally disintegrating formulation comprises an effective amount of a pharmaceutically active ingredient and a matrix, wherein the matrix contains an amino acid and pullulan. The orally disintegrating formulation can disintegrate rapidly in oral cavity and be taken without aid of water; Moreover, the formulation has a low hygroscopicity, so that the requirements for storing or producing the formulation is decreased, and the storage life is elongated to facilitate the administration by a patient and the preparation of the protein and vaccine drugs.

Abstract: The present invention provides methods for preparing compositions in blister packages using complex aluminum substrate materials, wherein said complex aluminum substrate materials comprise an intermediate aluminum layer, and first and second outer layers, wherein the material of the first outer layer differs from that of the second outer layer, and the flexural rigidity of the first outer layer differs from that of the second outer layer by 0-30%.

Abstract: A packaging box for medicaments, which can comprise: a bottom panel (1); a first-top panel (4); a second-top panel (5); a first-side panel (3a), being between said bottom panel (1) and first-top panel (4) and connected to them; a second-side panel (3b), being between said bottom panel (1) and second-top panel (5) and connected to them; a third-top panel (6), being connected to the second-top panel (5) and being opposing to said second-side panel (3b); some blisters (8) for the storage of medicaments, being provide don the third-top panel (6) and protruding therefrom; and supporting means (2) being provided on the internal surface of said bottom panel (1) so as to support said third-top panel (6).

Abstract: An orally disintegrating formulation and its preparation are provided. The orally disintegrating formulation comprises an effective amount of a pharmaceutically active ingredient and a matrix, wherein the matrix contains an amino acid and pullulan. The orally disintegrating formulation can disintegrate rapidly in oral cavity and be taken without aid of water; Moreover, the formulation has a low hygroscopicity, so that the requirements for storing or producing the formulation is decreased, and the storage life is elongated to facilitate the administration by a patient and the preparation of the protein and vaccine drugs.