Abstract: The present invention provides a method of implementing an intra prediction computation applied to the H.264 digital video coding and a device. The method according to present invention of implementing the intra prediction computation applied to the H.264 video coding comprises selecting an image block to be intra-predicted and extracting the neighboring pixel values of said block; determining the prediction mode of said block, and perform first adding operation on said neighboring pixel values when the prediction mode is one of Diagonal_Down_Left, Diagonal_Down_Right, Vertical_Right, Horizontal_Down, Vertical_Left, and Horizontal_Up; performing first shifting operation and second adding operation on the result of first adding operation respectively; performing second shifting operation on the result of second adding operation; selecting a corresponding value to output from the results of first and second shifting operation according to said prediction mode and size of block.

Abstract: The present invention provides a method of implementing an intra prediction computation applied to the H.264 digital video coding and a device. The method according to present invention of implementing the intra prediction computation applied to the H.264 video coding comprises selecting an image block to be intra-predicted and extracting the neighboring pixel values of said block; determining the prediction mode of said block, and perform first adding operation on said neighboring pixel values when the prediction mode is one of Diagonal_Down_Left, Diagonal_Down_Right, Vertical_Right, Horizontal_Down, Vertical_Left, and Horizontal_Up; performing first shifting operation and second adding operation on the result of first adding operation respectively; performing second shifting operation on the result of second adding operation; selecting a corresponding value to output from the results of first and second shifting operation according to said prediction mode and size of block.

Abstract: The invention is based on the discovery that compounds of Formula I are unexpectedly highly potent and selective inhibitors of the adenosine A1 receptor. Adenosine A1 antagonists can be useful in the prevention and/or treatment of numerous diseases, including cardiac and circulatory disorders, degenerative disorders of the central nervous system, respiratory disorders, and many diseases for which diuretic treatment is suitable.

Abstract: The invention is based on the discovery that compounds of Formula I are unexpectedly highly potent and selective inhibitors of the adenosine A1 receptor. Adenosine A1 antagonists can be useful in the prevention and/or treatment of numerous diseases, including cardiac and circulatory disorders, degenerative disorders of the central nervous system, respiratory disorders, and many diseases for which diuretic treatment is suitable.

Abstract: The invention is based on the discovery that compounds of Formula I are unexpectedly highly potent and selective inhibitors of the adenosine A1 receptor. Adenosine A1 antagonists can be useful in the prevention and/or treatment of numerous diseases, including cardiac and circulatory disorders, degenerative disorders of the central nervous system, respiratory disorders, and many diseases for which diuretic treatment is suitable.

Abstract: The invention is based on the discovery that compounds of Formula I are unexpectedly highly potent and selective inhibitors of the adenosine A1 receptor. Adenosine A1 antagonists can be usefull in the prevention and/or treatment of numerous diseases, including cardiac and circulatory disorders, degenerative disorders of the central nervous system, respiratory disorders, and many diseases for which diuretic treatment is suitable. In one embodiment, the invention features a compound of formula I: wherein: R3 is an optionally substituted bicyclic, tricylic, or pentacyclic group selected from:  and wherein R1, R2, R6, X1, X2, and Z are as described in the specification.