Patents by Inventor He Xu

He Xu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for generating primate trophoblasts
    Publication number: 20040005701
    Abstract: The first method to cause a culture of human and other primate stem cells to directly and uniformly differentiate into a committed cell lineage is disclosed. Treatment of primate stem cells with a single protein trophoblast induction factor causes the cells to transform into human trophoblast cells, the precursor cells of the placenta. Several protein factors including bone morphogenic protein 4 (BMP4), BMP2, BMP7, and growth and differentiation factor 5 can serve as trophoblast-inducting factors.
    Type: Application
    Filed: March 14, 2003
    Publication date: January 8, 2004
    Inventors: Ren-He Xu, James A. Thomson
  • Method for identifying intercellular protein factors
    Publication number: 20030022159
    Abstract: A method is disclosed for identifying the intercellular protein factors which cells use to provide developmental signals to adjacent cells in an organism. The method is based on the use of a phage display library of cDNA from the signaling cells. The method is being used to identify the factors produced by fibroblasts which inhibit differentiation in embryonic stem cells, but is broadly useful for identifying the proteins that signal between cells.
    Type: Application
    Filed: February 6, 2002
    Publication date: January 30, 2003
    Inventors: James A. Thomson, Ren-He Xu