Abstract: The invention provides anti-oncostatin M receptor-? (OSMR) antigen binding proteins, e.g., antibodies and functional fragments, derivatives, muteins, and variants thereof. OSMR antigen binding proteins interfere with binding of OSM and/or IL-31 to OSMR. In some embodiments, anti-OSMR antigen binding proteins are useful tools in studying diseases and disorders associated with OSMR and are particularly useful in methods of treating diseases and disorders associated with OSMR and binding of OSM and/or IL-31 to OSMR.

Abstract: Antigen binding proteins that bind to human IL-23 protein arc provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same as well as use of IL-23 antigen binding proteins for diagnostic and therapeutic purposes arc also provided.

Abstract: A seat module adapted to be attached to a seat having mechanical parts and electric devices for seat operation in a motor vehicle includes at least one operating cable for activating at least one device, and a module plate formed with a mounting feature for attaching to the seat and a retention feature for attaching the at least one operating cable. An end portion of the operating cable is temporarily stowed on the module plate in a pre-assembled state where the operating cable is attached to the module plate, and the end portion of the operating cable is connected to the electric devices and/or mechanical parts of the seat in an assembled state where the module plate with the retained operating cables is securely mounted to the seat.

Abstract: A seat module adapted to be attached to a seat having mechanical parts and electric devices for seat operation in a motor vehicle includes at least one operating cable for activating at least one device, and a cushion suspension module adapted to support a cushion of the seat having a plurality of cushion suspension wires for attaching to the seat and at least one module plates coupled with the cushion suspension wires. An end portion of the operating cable is temporarily stowed on the cushion suspension module in a pre-assembled state where the operating cable is attached to the cushion suspension module, and the end portion of the operating cable is connected to the electric devices and/or mechanical parts of the seat in an assembled state where the cushion suspension module with the attached operating cables is securely mounted to the seat.

Abstract: A seat module attached to a seat having mechanical parts for seat actuation in a motor vehicle includes at least one mechanical control cable for the seat actuation, and a module plate formed with a mounting feature for attaching to the seat and a retention feature for attaching the mechanical control cable. An end portion of the mechanical control cable is temporarily stowed on the module plate in a pre-assembled state where the mechanical control cable is attached to the module plate, and the end portion of the mechanical control cable is connected to the mechanical parts of the seat in an assembled state where the module plate with the attached mechanical control cable is securely mounted to the seat.

Abstract: Methods and/or systems for a flexible loan application process for financing a vehicle may provide multiple user interface channels (which include both multiple manual and electronic user interface channels) via which the applicant may initiate, monitor, access, and/or close the loan, as the applicant desires. Further, for a single loan application, the applicant may only need to provide limited information at the outset. Subsequently, the flexible loan application process may provide multiple approved loan offers of varying loan amounts and/or loan terms based upon the limited applicant information received. The applicant may then select one or more of the offers to customize, within approved limits, to generate a vehicle loan that best suits his or her preferences without having to restart the entire loan application process.

Abstract: Technologies for managing network traffic through heterogeneous fog network segments of a fog network include a fog node deployed in a fog network segment. The fog node is configured to receive a fog frame that includes control instructions. The fog node is further configured to perform a route selection action to identify a preferred target fog node based on the control instructions, perform action(s) based on the control instructions and network characteristic(s) of the fog network segment relative to corresponding network characteristic(s) of the different fog network segment, and generate updated control instructions based on at least one network characteristic of the different fog network segment. Additionally, the fog node is configured to replace the original control instructions of the received fog frame with the updated control instructions and transmit the received fog frame with the updated control instructions to the preferred target fog node. Other embodiments are described and claimed.

Abstract: The invention relates to compounds of formula (I): wherein R1, R2, R3, R4, L and A are as defined in the description and claims, or pharmaceutically acceptable salts thereof having mTOR kinase inhibitor activity. The invention also relates to pharmaceutical compositions including a compound of formula (I) or a pharmaceutically acceptable salt thereof, and to the use of a compound of formula (I) or a pharmaceutically acceptable salt thereof in therapy, including in the treatment of a disease or condition for which an mTOR kinase inhibitor activity is indicated, and in particular the treatment of idiopathic pulmonary fibrosis.

Abstract: An ostomy barrier includes an adhesive layer having a body-facing side, a distal side opposite to the body-facing side, and an opening, a seal substantially aligned with the opening, the seal having an aperture configured to receive a stoma therein, and a flexible connector extending between the seal and the adhesive layer to connect the seal to the adhesive layer. The flexible connector formed from a flexible material to allow relative movement between the seal and the adhesive layer.

Abstract: The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.

Abstract: A hair conditioner composition comprising: a. an aqueous carrier; b. from about 1 wt % to about 12 wt % of BVE; and c. from about 1 wt % to about 12 wt % of at least two fatty alcohols.

Abstract: A hair conditioner composition comprising: a. an aqueous carrier; b. from about 1 wt % to about 12 wt % of BVE; and c. from about 1 wt % to about 12 wt % of at least two fatty alcohols.

Abstract: The invention provides a transgenic corn event MON 95379, plants, plant cells, seeds, plant parts, progeny plants, and commodity products comprising event MON 95379. The invention also provides polynucleotides specific for event MON 95379 and methods for using and detecting event MON 95379 as well as plants, plant cells, seeds, plant pails, progeny plants, and commodity products comprising event MON 95379.

Abstract: A hair conditioner composition comprising: a. an aqueous carrier; b. from about 0.25 wt % to about 8 wt % of BVE; and c. from about 0.25 wt % to about 8 wt % of fatty alcohol(s).

Abstract: Disclosed are compositions, methods and kits for determining the presence, absence, amount, copy number, or other characteristics of one or more polynucleotide sequences in two or more samples and use thereof in genotyping, evaluation of copy number variation, expression analysis, determination of splice variants and fusion genes, and other genetic analyses.

Abstract: The invention provides compositions and methods of treating cancer in a patient with a combination therapy comprising a fusion protein of SEQ ID NO: 1 in combination with an immune checkpoint inhibitor. Preferably the patient has failed to achieve complete or partial response with prior or ongoing treatment with an immune checkpoint inhibitor.

Abstract: Processes and apparatus for analyzing fluid properties of a stream are described. The processes utilize a simulated moving bed system and a rotary valve. The processes involve sending a portion of the pump-around stream to a side chamber where the moisture content of the adsorbent in the side chamber or one or more fluid properties of the stream or both are measured using an analyzer specific to each fluid property.

Abstract: In example implementations, a printing device is provided. The printing device includes a printer module, a plurality of dryer modules, and a side exit unit. The printer module is to print on a continuous web of print media. The plurality of dryer modules is located downstream from the printer module. The continuous web of print media is fed in a wrap-around direction from an outermost dryer module to a center dryer module. The side exit unit is coupled to the center dryer module to redirect the continuous web of print media along an outer side of the plurality of dryer modules.

Abstract: A vehicle body structure includes an inner sill member, an outer sill member and a first reinforcement bracket. The inner sill member has an inner upper flange, a horizontally extending section and an inner lower flange extending downward from the horizontally extending section. The outer sill member has an outer upper flange and an outer lower flange. The inner upper flange and the outer upper flanges are fixedly attached to one another. The inner lower flange and the outer lower flanges are fixedly attached to one another defining a sill structure with hollow interior. The first reinforcement bracket is disposed within the hollow interior and has an outboard portion fixedly attached to the outer sill member and an inboard portion fixedly attached to the horizontally extending section of the inner sill member.

Abstract: Embodiments of the present invention disclose a computer-implemented methodology for automatically indicating in a computer-aided dispatch system for a plurality of assignable participants, such as emergency vehicles, to be dispatched to one of a plurality of facilities, whether a facility is in a diverting status or a receiving status. A centralized database receives a change in status for a vehicle for use in determining the status of a facility. In response to receiving the change in status for the vehicle, the status information about the vehicle including a current status and a prior status is transmitted to one or more client programs. A client program receives the current status and the prior status of the vehicle and uses the current status and prior status of the vehicle along with a criteria set to determine if any of the plurality of facilities' status should be changed from receiving to diverting or from diverting to receiving.