Patents by Inventor Heather Finlay

Heather Finlay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 6-HYDROXY-4-OXO-1,4-DIHYDROPYRIMIDINE-5-CARBOXAMIDES AS APJ AGONISTS
    Publication number: 20190002441
    Abstract: The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are APJ agonists which may be used as medicaments.
    Type: Application
    Filed: September 6, 2018
    Publication date: January 3, 2019
    Inventors: Zulan Pi, Donna M. Bilder, Robert Paul Brigance, Heather Finlay, Wen Jiang, James A. Johnson, R. Michael Lawrence, Wei Meng, Michael C. Myers, Monique Phillips, George O. Tora, Xiaojun Zhang
  • HETEROARYLHYDROXYPYRIMIDINONES AS AGONISTS OF THE APJ RECEPTOR
    Publication number: 20180362508
    Abstract: The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are APJ agonists which may be used as medicaments, in particular for treating cardiovascular disorders.
    Type: Application
    Filed: December 15, 2016
    Publication date: December 20, 2018
    Inventors: Michael C. Myers, R. Michael Lawrence, Donna M. Bilder, Wei Meng, Zulan Pi, Robert Paul Brigance, Heather Finlay
  • 6-hydroxy-4-oxo-1,4-dihydropyrimidine-5-carboxamides as APJ agonists
    Patent number: 10106528
    Abstract: The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are APJ agonists which may be used as medicaments.
    Type: Grant
    Filed: March 24, 2017
    Date of Patent: October 23, 2018
    Assignee: Bristol-Myers Squibb Company
    Inventors: Zulan Pi, Donna M. Bilder, Robert Paul Brigance, Heather Finlay, Wen Jiang, James A. Johnson, R. Michael Lawrence, Wei Meng, Michael C. Myers, Monique Phillips, George O. Tora, Xiaojun Zhang
  • 2,4-DIHYDROXY-NICOTINAMIDES AS APJ AGONISTS
    Publication number: 20180297954
    Abstract: The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, O and compositions comprising any of such novel compounds. These compounds are APJ agonists which may be used as medicaments.
    Type: Application
    Filed: October 13, 2016
    Publication date: October 18, 2018
    Inventors: Soong-Hoon Kim, Hannguang J. Chao, Heather Finlay, Ji Jang, James A. Johnson, R. Michael Lawrence, Michael C. Myers, Monique Phillips, George O. Tora, Wei Meng
  • QUINAZOLINES AS POTASSIUM ION CHANNEL INHIBITORS
    Publication number: 20180030034
    Abstract: A compound of formula I wherein A, X, Y, Z, R1 and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
    Type: Application
    Filed: October 4, 2017
    Publication date: February 1, 2018
    Inventors: John Lloyd, Heather Finlay, Prashantha Gunaga, Abhisek Banerjee, Ashokkumar Adisechan
  • Quinazolines as potassium ion channel inhibitors
    Patent number: 9822096
    Abstract: A compound of formula I wherein A, X, Y, Z, R1 and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
    Type: Grant
    Filed: August 29, 2016
    Date of Patent: November 21, 2017
    Assignee: Bristol-Myers Squibb Company
    Inventors: James A. Johnson, Heather Finlay, James Neels, Naveen Kumar Dhondi, Ashokkumar Adisechan
  • 6-HYDROXY-4-OXO-1,4-DIHYDROPYRIMIDINE-5-CARBOXAMIDES AS APJ AGONISTS
    Publication number: 20170275272
    Abstract: The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are APJ agonists which may be used as medicaments.
    Type: Application
    Filed: March 24, 2017
    Publication date: September 28, 2017
    Inventors: Zulan Pi, Donna M. Bilder, Robert Paul Brigance, Heather Finlay, Wen Jiang, James A. Johnson, R. Michael Lawrence, Wei Meng, Michael C. Myers, Monique Phillips, George O. Tora, Xiaojun Zhang
  • QUINAZOLINES AS POTASSIUM ION CHANNEL INHIBITORS
    Publication number: 20160362396
    Abstract: A compound of formula I wherein A, X, Y, Z, R1 and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
    Type: Application
    Filed: August 29, 2016
    Publication date: December 15, 2016
    Inventors: James A. Johnson, Heather Finlay, James Neels, Naveen Kumar, Ashokkumar Adisechan
  • Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors
    Patent number: 9493412
    Abstract: The present invention provides compounds of Formula (I): (I), as defined in the specification and compositions comprising any of such novel compounds. These compounds are endothelial lipase inhibitors which may be used as medicaments.
    Type: Grant
    Filed: September 24, 2012
    Date of Patent: November 15, 2016
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jennifer X. Qiao, Heather Finlay, Ji Jiang, John Lloyd, Carol Hui Hu, Zulan Pi, George O. Tora, James Neels, Jon J. Hangeland, Todd J. Friends
  • SULFONE AMIDE LINKED BENZOTHIAZOLE INHIBITORS OF ENDOTHELIAL LIPASE
    Publication number: 20160326125
    Abstract: The present invention provides compounds of Formula (I) as defined in the specification and compositions comprising any of such novel compounds. These compounds are endothelial lipase inhibitors which may be used medicaments.
    Type: Application
    Filed: January 5, 2015
    Publication date: November 10, 2016
    Inventors: James A. Johnson, Zulan Pi, Jennifer X. Qiao, Soong-Hoon Kim, Tammy C. Wang, Ji Jiang, Heather Finlay, John Lloyd
  • Pyrrolopyridazines as potassium ion channel inhibitors
    Patent number: 9458164
    Abstract: A compound of formula (I) wherein A, R1, R3, and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: October 4, 2016
    Assignee: Bristol-Myers Squibb Company
    Inventors: Heather Finlay, Ashok Kumar Adisechan, Prashantha Gunaga, John Lloyd, Srinivasu Pothukanuri
  • Isoquinolines as potassium ion channel inhibitors
    Patent number: 9458133
    Abstract: A compound of formula (I) (I) wherein A, R1, R1a, R3 and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: October 4, 2016
    Assignee: Bristol-Myers Squibb Company
    Inventors: Heather Finlay, Ashok Kumar Adisechan, Naveen Kumar Dhondi, Prashantha Gunaga, John Lloyd, Srinivasu Pothukanuri
  • Quinazolines as potassium ion channel inhibitors
    Patent number: 9458114
    Abstract: A compound of formula I wherein A, X, Y, Z, R1 and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: October 4, 2016
    Assignee: Bristol-Myers Squibb Company
    Inventors: James A. Johnson, John Lloyd, Heather Finlay, Ji Jiang, James Neels, Naveen Kumar Dhondi, Prashantha Gunaga, Abhisek Banerjee, Ashokkumar Adisechan
  • Pyrrolotriazines as potassium ion channel inhibitors
    Patent number: 9403834
    Abstract: A compound of formula (I), wherein A, R1, R3, and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: August 2, 2016
    Assignee: Bristol-Myers Squibb Company
    Inventors: Heather Finlay, Ashok Kumar Adisechan, Prashantha Gunaga, John Lloyd, Srinivasu Pothukanuri
  • Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors
    Patent number: 9249096
    Abstract: The present invention provides compounds of Formula (I): as defined in the specification and compositions comprising any of such novel compounds. These compounds are endothelial lipase inhibitors which may be used as medicaments. The disclosure also provides a novel method of treating diseases or conditions related to the activity of endothelial lipase by use of compounds according to Formula (II): as defined in the specification and compositions comprising any of the compounds.
    Type: Grant
    Filed: September 26, 2012
    Date of Patent: February 2, 2016
    Assignee: Bristol-Myers Squibb Company
    Inventors: Lynn Abell, Leonard Adam, Cullen L. Cavallaro, Heather Finlay, Todd J. Friends, Jon J. Hangeland, Ji Jiang, R. Michael Lawrence, Jennifer X. Qiao, Carol Hui Hu, Tammy C. Wang
  • Phthalazines as potassium ion channel inhibitors
    Patent number: 9242966
    Abstract: A compound of formula (I) wherein A, R1, R3, and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: January 26, 2016
    Assignee: Bristol-Myers Squibb Company
    Inventors: Heather Finlay, Ashok Kumar Adisechan, Prashantha Gunaga, John Lloyd, Pothukanuri Srinivasu
  • PYRROLOPYRIDAZINES AS POTASSIUM ION CHANNEL INHIBITORS
    Publication number: 20160016961
    Abstract: A compound of formula (I) wherein A, R1, R3, and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
    Type: Application
    Filed: March 10, 2014
    Publication date: January 21, 2016
    Inventors: Heather Finlay, Ashok Kumar Adisechan, Prashantha Gunaga, John Lloyd, Srinivasu Pothukanuri
  • ISOQUINOLINES AS POTASSIUM ION CHANNEL INHIBITORS
    Publication number: 20160016933
    Abstract: A compound of formula (I) (I) wherein A, R1, R1a, R3 and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
    Type: Application
    Filed: March 10, 2014
    Publication date: January 21, 2016
    Inventors: Heather Finlay, Ashok Kumar Adisechan, Naveen Kumar Dhondi, Prashantha Gunaga, John Lloyd, Srinivasu Pothukanuri
  • PYRROLOTRIAZINES AS POTASSIUM ION CHANNEL INHIBITORS
    Publication number: 20160009719
    Abstract: A compound of formula (I), wherein A, R1, R3, and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
    Type: Application
    Filed: March 10, 2014
    Publication date: January 14, 2016
    Inventors: Heather Finlay, Ashok Kumar Adisechan, Prashantha Gunaga, John Lloyd, Srinivasu Pothukanuri
  • Ketone linked benzothiazole inhibitors of endothelial lipase
    Patent number: 9169240
    Abstract: The present invention provides compounds of Formula (I): as defined in the specification and compositions comprising any of such novel compounds. These compounds are endothelial lipase inhibitors which may be used as medicament.
    Type: Grant
    Filed: September 5, 2013
    Date of Patent: October 27, 2015
    Assignee: Bristol-Myers Squibb Company
    Inventors: George O. Tora, Heather Finlay, Carol Hui Hu, Ji Jiang, James A. Johnson, Soong-Hoon Kim, John Lloyd, Brandon Parkhurst, Zulan Pi, Jennifer X. Qiao, Tammy C. Wang