Patents by Inventor Heather Harding

Heather Harding has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF SCREENING TEST SUBSTANCES FOR TREATING OR PREVENTING A DISEASE MEDIATED BY PLASMA CELLS
    Publication number: 20100105064
    Abstract: The present invention relates to a method of screening a compound for potential effectiveness in treating or preventing a mammalian disease mediated by plasma cells or a mammalian disease caused by virus infection of mammalian cells. Compounds are tested for their ability to inhibit IRE1-mediated processing of untranslatable XBP-1 mRNA into translatable XBP-1 mRNA. Drugs that are useful in treating or preventing a mammalian disease mediated by plasma cells and a method for detecting XBP-1 activity in living cells are also described.
    Type: Application
    Filed: December 30, 2009
    Publication date: April 29, 2010
    Applicant: NEW YORK UNIVERSITY
    Inventors: David Ron, Marcella Calfon, Heather Harding, Yuhong Zhang
  • Method of screening test substances for treating or preventing a disease mediated by plasma cells
    Patent number: 7666587
    Abstract: The present invention relates to a method of screening a compound for potential effectiveness in treating or preventing a mammalian disease mediated by plasma cells or a mammalian disease caused by virus infection of mammalian cells. Compounds are tested for their ability to inhibit IRE1-mediated processing of untranslatable XBP-1 mRNA into translatable XBP-1 mRNA. Drugs that are useful in treating or preventing a mammalian disease mediated by plasma cells and a method for detecting XBP-1 activity in living cells are also described.
    Type: Grant
    Filed: April 11, 2003
    Date of Patent: February 23, 2010
    Assignee: New York University
    Inventors: David Ron, Marcella Calfon, Heather Harding, Yuhong Zhang
  • Method of screening test substances for treating or preventing a disease mediated by plasma cells
    Publication number: 20030224428
    Abstract: The present invention relates to a method of screening a compound for potential effectiveness in treating or preventing a mammalian disease mediated by plasma cells or a mammalian disease caused by virus infection of mammalian cells. Compounds are tested for their ability to inhibit IRE1-mediated processing of untranslatable XBP-1 mRNA into translatable XBP-1 mRNA. Drugs that are useful in treating or preventing a mammalian disease mediated by plasma cells and a method for detecting XBP-1 activity in living cells are also described.
    Type: Application
    Filed: April 11, 2003
    Publication date: December 4, 2003
    Inventors: David Ron, Marcella Calfon, Heather Harding, Yuhong Zhang