Patents by Inventor Heather Laurence JONES

Heather Laurence JONES has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MULTI-SITE SPECIFIC INTEGRATION CELLS FOR DIFFICULT TO EXPRESS PROTEINS
    Publication number: 20200002727
    Abstract: The present disclosure relates to a site-specific integration (SSI) mammalian cell that comprises at least two distinct recombination target sites (RTS) wherein two RTS are chromosomally-integrated within the NL1 locus or the NL2 locus. The disclosure also relates to a SSI mammalian cell comprising at least four distinct RTS wherein two RTS are chromosomally-integrated within the NL1 or the NL2 locus and two RTS are chromosomally-integrated within a separate locus. The disclosure also relates to methods for using the SSI mammalian cell to produce recombinant protein expression cell lines that can express difficult to express proteins.
    Type: Application
    Filed: February 17, 2018
    Publication date: January 2, 2020
    Inventors: Marc FEARY, Robert J. YOUNG, Mark MOFFAT, Gerald Fries CASPERSON, Heather Laurence JONES, Lin ZHANG