Patents by Inventor HEATHER O'KEEFE

HEATHER O'KEEFE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and kit for hybridization anaylsis using peptide nucleic acid probes
    Publication number: 20050053944
    Abstract: A method composition and apparatus for the hybridization and separation of molecules having a desired target sequence in a sample by contacting a sample of single stranded nucleic acids with a detectable PNA probe having a sequence complementary to the target sequence so that the target sequence, if present, will hybridize with the detectable probe to form a detectable duplex, and then separating the duplex in a denaturing medium from unbound sample components by electrophoresis. The invention also relates to methods compositions and apparatus for the hybridization and separation of molecules having a desired target sequence in a mixed sample of single stranded nucleic acids and their complementary strands by contacting the sample with a detectable PNA probe.
    Type: Application
    Filed: August 7, 2003
    Publication date: March 10, 2005
    Inventors: Martin Fuchs, Michael Egholm, Heather O'Keefe, Xian-Wei Yao
  • METHODS AND KIT FOR HYBRIDIZATION ANALYSIS USING PEPTIDE NUCLEIC ACID PROBES
    Publication number: 20020012902
    Abstract: A method composition and apparatus for the hybridization and separation of molecules having a desired target sequence in a sample by contacting a sample of single stranded nucleic acids with a detectable PNA probe having a sequence complementary to the target sequence so that the target sequence, if present, will hybridize with the detectable probe to form a detectable duplex, and then separating the duplex in a denaturing medium from unbound sample components by electrophoresis. The invention also relates to methods compositions and apparatus for the hybridization and separation of molecules having a desired target sequence in a mixed sample of single stranded nucleic acids and their complementary strands by contacting the sample with a detectable PNA probe.
    Type: Application
    Filed: October 4, 1996
    Publication date: January 31, 2002
    Inventors: MARTIN FUCHS, MICHAEL EGHOLM, HEATHER O'KEEFE, XIAN-WEI YAO