Abstract: The present disclosure relates to methods of facilitating bone growth. The method may include positioning a device around at least a portion of a bone exhibiting a defect, the device capable of retaining bone segments and micro-structured particles. The method may also include applying micro-structure particles within the device to the defect, wherein each of the micro-structure particles include at least one pore therein. In addition, the method may include aligning at least a portion of the micro-structure particles and applying a polymer to the particles and solidifying the polymer.

Abstract: The present disclosure is directed at methods and apparatus to evaluate and monitor healing progress of wound and/or to generate data to modify or identify a treatment protocol. Fluid exudate removed from the wound by a negative pressure therapy device may now be analyzed to identify the progress of wound healing, such as whether healing is progressing in a positive manner or experiencing one or more impediments. The fluid exudates may be specifically analyzed for one or more analytes indicative of one or more of the biochemical reactions that may occur during wound recovery. In addition, one may separately utilize optical sensors integrated into a dressing enclosure, optionally in those dressings employed in a negative pressure therapy device. Such optical sensors may then illuminate the wound and collect information regarding the wound via a light scattering type response.

Abstract: An artificial functional spinal unit including an expandable intervertebral implant that can be inserted via a posterior surgical approach and used with one or more facet replacement devices to provide an anatomically correct range of motion is described. Lordotic and non-lordotic expandable, articulating implants and cages are described, along with embodiments of facet replacement devices and instruments for insertion. Methods of insertion are also described.

Abstract: A stabilization system for a human spine is provided comprising at least two dynamic interbody device and at least one dynamic posterior stabilization system. In some embodiments the stabilization system comprises a pair of dynamic interbody devices and a pair of dynamic posterior stabilization systems. The dynamic interbody devices may work in conjunction with the dynamic posterior stabilization systems to allow for movement of vertebrae coupled to the stabilization system. The dynamic posterior stabilization systems may provide resistance to movement that mimics the resistance provided by a normal functional spinal unit. In some embodiments, a bridge may couple a dynamic interbody device to a dynamic posterior stabilization system.

Abstract: A stabilization system for a human spine is provided comprising at least one dynamic interbody device and at least one dynamic posterior stabilization system. In some embodiments the stabilization system comprises a pair of dynamic interbody devices and a pair of dynamic posterior stabilization systems. In some embodiments, a bridge may couple a dynamic interbody device to a dynamic posterior stabilization system. In some embodiments, an elongated member of the dynamic posterior stabilization system may be curved.

Abstract: A stabilization system for a human spine is provided comprising at least one dynamic interbody device and at least two dynamic posterior stabilization systems. The dynamic posterior stabilization system may be coupled on contralateral sides of vertebrae. In some embodiments, a bridge may couple a dynamic interbody device to a dynamic posterior stabilization system.

Abstract: An expandable intervertebral implant for insertion between vertebrae of a human spine is described. The intervertebral implant includes an upper body that engages a first vertebra of the human spine, a lower body that engages a second vertebra of the human spine, an insert, and an advancing element. The advancing element may engage the insert such that advancement of the advancing element causes the insert to at least partially rotate between the upper body and the lower body. Rotation of the insert may cause the insert to interact with at least a portion of the upper body or at least a portion of the lower body to increase a separation distance between the upper body and the lower body, thereby increasing a height of the intervertebral implant after insertion of the implant between the first vertebra and the second vertebra of the human spine.

Abstract: An articulating expandable intervertebral implant for insertion between vertebrae of a human spine is described. The articulating expandable intervertebral implant includes an upper body that engages a first vertebra of the human spine, a lower body that engages a second vertebra of the human spine, and an elongated member. The superior surface of the lower body includes a channel. A portion of the inferior surface of the upper body may be substantially concave. The elongated member may include a cam portion along a length of the elongated member. The elongated member may be positioned in the channel of the lower body. The substantially concave portion of the upper body may contact the elongated member, such that rotation of the elongated member about a longitudinal axis of the elongated member increases a height and/or increases articulation of the intervertebral implant after insertion of the intervertebral implant.

Abstract: A sensor for measuring stress corrosion cracking and methods of using the sensor. The sensor is a MEMS device and has a cantilevered beam made from a material of interest. The sensor has on-chip electrical connections for measuring electrical characteristics that indicate cracking of the beam. The sensor may further have on-chip actuators for applying stress to the beam.

Abstract: A sensor for measuring stress corrosion cracking and methods of using the sensor. The sensor is a MEMS device and has a cantilevered beam made from a material of interest. The sensor has on-chip electrical connections for measuring electrical characteristics that indicate cracking of the beam. The sensor may further have on-chip actuators for applying stress to the beam.