Abstract: Systems, devices, and techniques are described for calibrating a medical device that senses ECAP signals from a patient's nerve tissue. For example a method includes instructing, with processing circuitry, stimulation circuitry of a medical device to deliver, on stimulation electrodes of the medical device, an electrical stimulation signal having an amplitude substantially equal to zero to a patient, entering, with the processing circuitry subsequent to instructing the stimulation circuitry to deliver the electrical stimulation signal, a passive recharge state on stimulation electrode circuitry, and auto-zeroing, with the processing circuitry, inputs to an operational amplifier of sensing circuitry electrically coupled to sensing electrodes of the medical device while the stimulation electrode circuitry is in the passive recharge state.

Abstract: Systems, devices, and techniques are described for calibrating a medical device that senses ECAP signals from a patient's nerve tissue. For example a method includes: instructing, with processing circuitry, stimulation circuitry of a medical device to deliver, on stimulation electrodes of the medical device, an electrical stimulation signal having an amplitude substantially equal to zero to a patient; entering, with the processing circuitry subsequent to instructing the stimulation circuitry to deliver the electrical stimulation signal, a passive recharge state on stimulation electrode circuitry; and auto-zeroing, with the processing circuitry, inputs to an operational amplifier of sensing circuitry electrically coupled to sensing electrodes of the medical device while the stimulation electrode circuitry is in the passive recharge state.

Abstract: A system for providing therapy to a patient includes stimulation generation circuitry, sensing circuitry, and processing circuitry. The processing circuitry is configured to cause storage of a first voltage at a first terminal at a first calibration capacitor and storage of a second voltage at a second terminal at a second calibration capacitor. The processing circuitry is configured to switch out a first calibration switch to prevent the first voltage stored at the first calibration capacitor from changing and switch out a second calibration switch to prevent the second voltage stored at the second calibration capacitor from changing and determine, with the sensing circuitry, a sensing signal based on the first voltage offset by a first calibration voltage stored by the first capacitor and based on the second voltage offset by a second calibration voltage stored by the second capacitor.