Patents by Inventor Hecheng Hu

Hecheng Hu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200246617
    Abstract: Systems and methods for reducing or inhibiting an inflammatory response in a patient include a source of energy and one or more electrodes coupled to the source of energy and positionable near a vagus nerve of the patient to deliver the electrical impulse to the vagus nerve. The electrical impulse is sufficient to either inhibit a release of a pro-inflammatory cytokine, such as TNF-alpha, or increase an anti-inflammatory competence of a cytokine, such as TGF-beta, in the patient, thereby inhibiting the inflammatory response. The electrical impulse may be delivered transcutaneously and non-invasively through an outer skin surface of the patient to the vagus nerve.
    Type: Application
    Filed: April 21, 2020
    Publication date: August 6, 2020
    Inventors: Joseph P. Errico, Francis R. Amato, Steven M. Mendez, Hecheng Hu, Bruce J. Simon
  • Publication number: 20190198166
    Abstract: A system includes: a processor; a memory coupled to the processor, wherein the memory stores a first content; a medical device coupled to the processor; and a reader coupled to the processor, wherein the reader is configured to read a second content from a storage medium other than the memory such that the processor switches the medical device from a first mode to a second mode based on the first content corresponding to the second content.
    Type: Application
    Filed: December 21, 2018
    Publication date: June 27, 2019
    Inventors: Joseph P. Errico, Francis R. Amato, Steven M. Melendez, Hecheng Hu
  • Publication number: 20190111255
    Abstract: A system includes: a processor; a memory coupled to the processor, wherein the memory stores a first content; a medical device coupled to the processor; and a reader coupled to the processor, wherein the reader is configured to read a second content from a storage medium such that the processor switches the medical device from a first mode to a second mode based on the first content corresponding to the second content.
    Type: Application
    Filed: December 21, 2018
    Publication date: April 18, 2019
    Inventors: Joseph P. Errico, Francis R. Amato, Steven M. Melendez, Hecheng Hu, Bruce J. Simon
  • Patent number: 9821164
    Abstract: Devices, systems and methods for treating bronchial constriction related to asthma, anaphylaxis or chronic obstructive pulmonary disease wherein the treatment includes stimulating selected nerve fibers responsible for smooth muscle dilation at a selected region within a patient's neck, thereby reducing the magnitude of constriction of bronchial smooth muscle.
    Type: Grant
    Filed: July 31, 2014
    Date of Patent: November 21, 2017
    Assignee: Electrocore, LLC
    Inventors: Joseph P. Errico, Steven Mendez, Bruce J. Simon, James R. Pastena, Hecheng Hu, Arthur Ross
  • Patent number: 9037246
    Abstract: Methods and devices for treating bronchial constriction related to asthma and anaphylaxis wherein the treatment includes providing an electrical impulse to a selected region of the vagus nerve and/or the lungs of a patient suffering from bronchial constriction.
    Type: Grant
    Filed: May 25, 2010
    Date of Patent: May 19, 2015
    Assignee: Electrocore, LLC
    Inventors: Joseph P. Errico, James R. Pastena, Steven Mendez, Hecheng Hu, Arthur Ross
  • Publication number: 20140343565
    Abstract: Devices, systems and methods for treating bronchial constriction related to asthma, anaphylaxis or chronic obstructive pulmonary disease wherein the treatment includes stimulating selected nerve fibers responsible for smooth muscle dilation at a selected region within a patient's neck, thereby reducing the magnitude of constriction of bronchial smooth muscle.
    Type: Application
    Filed: July 31, 2014
    Publication date: November 20, 2014
    Inventors: Joseph P. Errico, Steven Mendez, Bruce J. Simon, James R. Pastena, Hecheng Hu, Arthur Ross
  • Patent number: 8812112
    Abstract: Devices, systems and methods for treating bronchial constriction related to asthma, anaphylaxis or chronic obstructive pulmonary disease wherein the treatment includes stimulating selected nerve fibers responsible for smooth muscle dilation at a selected region within a patient's neck, thereby reducing the magnitude of constriction of bronchial smooth muscle.
    Type: Grant
    Filed: March 20, 2009
    Date of Patent: August 19, 2014
    Assignee: Electrocore, LLC
    Inventors: Joseph P. Errico, James R. Pastena, Steven Mendez, Hecheng Hu, Arthur Ross, Bruce Simon
  • Patent number: 8666496
    Abstract: The present invention provides systems, apparatus and methods for selectively applying electrical energy to body tissue. A device is provided with an electrode positioned within the interior of an enclosure and a fluid passage coupled to the enclosure for delivery of an electrically conductive fluid such that the electrically conductive fluid. The conductive fluid allows for the passage of electrical energy from the electrode through the fluid and the outer wall of the enclosure for treatment of tissue on or in a patient. The electrode does not directly contact the tissue of the patient, which reduces the potential for collateral tissue damage or necrosis and/or excessive electric fields in the tissue.
    Type: Grant
    Filed: February 17, 2013
    Date of Patent: March 4, 2014
    Assignee: Electrocore, LLC
    Inventors: Bruce Simon, Steven Mendez, Hecheng Hu, Richard P. Dickerson, James R. Pastena, Puyun Guo
  • Publication number: 20130204334
    Abstract: The present invention provides systems, apparatus and methods for selectively applying electrical energy to body tissue. A device is provided with an electrode positioned within the interior of an enclosure and a fluid passage coupled to the enclosure for delivery of an electrically conductive fluid such that the electrically conductive fluid. The conductive fluid allows for the passage of electrical energy from the electrode through the fluid and the outer wall of the enclosure for treatment of tissue on or in a patient. The electrode does not directly contact the tissue of the patient, which reduces the potential for collateral tissue damage or necrosis and/or excessive electric fields in the tissue.
    Type: Application
    Filed: February 17, 2013
    Publication date: August 8, 2013
    Applicant: ElectroCore LLC
    Inventors: Bruce Simon, Steven Mendez, Hecheng Hu, Richard P., James R. Pastena, Puyun Guo
  • Patent number: 8401650
    Abstract: The present invention provides systems, apparatus and methods for selectively applying electrical energy to body tissue. A device is provided having an enclosure within an outer wall formed from an electrically-permeable material to allow for electrical energy to pass from the interior of the enclosure through the outer wall. The device further includes an electrode positioned within the interior of the enclosure and a fluid passage coupled to the enclosure for delivery of an electrically conductive fluid into the interior of the enclosure such that the electrically conductive fluid couples the electrode with the electrically-permeable section of the outer wall. The conductive fluid allows for the passage of electrical energy from the electrode through the fluid and the outer wall of the enclosure for treatment of tissue on or in a patient.
    Type: Grant
    Filed: February 27, 2009
    Date of Patent: March 19, 2013
    Assignee: ElectroCore LLC
    Inventors: Bruce Simon, Steven Mendez, Hecheng Hu, Richard P. Dickerson, James R. Pastena, Puyun Guo
  • Patent number: 8209034
    Abstract: Methods and apparatus for treating ailments provide for: inserting a balloon-electrode device into an esophagus of a mammal, the balloon-electrode device including: (i) a nasogastral (NG) having an internal passageway and an external surface, (ii) at least one electrode coupled to the external surface of the NG tube, (iii) a conductor extending through the internal passageway of the NG tube and electrically connecting to the electrode, and (iv) a balloon surrounding the electrode and a portion of the NG tube; inflating the balloon with fluid such that the electrode is substantially centrally located within an interior volume of the balloon; and applying at least one electrical signal to the electrode via the conductor such that an electro-magnetic field emanates from the electrode to at least one of nerves and muscles of the mammal.
    Type: Grant
    Filed: December 18, 2008
    Date of Patent: June 26, 2012
    Assignee: ElectroCore LLC
    Inventors: Bruce Simon, Steven Mendez, Hecheng Hu, Richard P. Dickerson, James R. Pastena
  • Publication number: 20100241188
    Abstract: Devices, systems and methods for applying electrical impulse(s) to one or more selected nerves in or around the carotid sheath are described. An electrode assembly is introduced through a percutaneous penetration in a patient to a target location adjacent to, or in close proximity with, the carotid sheath. Once in position, one or more electrical impulses are applied through the electrode assembly to one or more selected nerves to stimulate, block or otherwise modulate the nerve(s) and acutely treat the patient's condition.
    Type: Application
    Filed: April 13, 2009
    Publication date: September 23, 2010
    Applicant: ElectroCore, Inc.
    Inventors: Joseph P. Errico, James R. Pastena, Steven Mendez, Hecheng Hu, Arthur Ross, Bruce Simon, Richard P. Dickerson
  • Publication number: 20100228318
    Abstract: Methods and devices for treating bronchial constriction related to asthma and anaphylaxis wherein the treatment includes providing an electrical impulse to a selected region of the vagus nerve and/or the lungs of a patient suffering from bronchial constriction.
    Type: Application
    Filed: May 25, 2010
    Publication date: September 9, 2010
    Applicant: ElectroCore LLC
    Inventors: Joseph P. Errico, James R. Pastena, Steven Mendez, Hecheng Hu, Arthur Ross
  • Patent number: 7747324
    Abstract: Methods and devices for treating bronchial constriction related to asthma and anaphylaxis wherein the treatment includes providing an electrical impulse to a selected region of the vagus nerve and/or the lungs of a patient suffering from bronchial constriction.
    Type: Grant
    Filed: November 1, 2006
    Date of Patent: June 29, 2010
    Assignee: ElectroCore LLC
    Inventors: Joseph P. Errico, James R. Pastena, Steven Mendez, Hecheng Hu, Arthur Ross
  • Publication number: 20100160996
    Abstract: Methods and apparatus for treating ailments provide for: inserting a balloon-electrode device into an esophagus of a mammal, the balloon-electrode device including: (i) a nasogastral (NG) having an internal passageway and an external surface, (ii) at least one electrode coupled to the external surface of the NG tube, (iii) a conductor extending through the internal passageway of the NG tube and electrically connecting to the electrode, and (iv) a balloon surrounding the electrode and a portion of the NG tube; inflating the balloon with fluid such that the electrode is substantially centrally located within an interior volume of the balloon; and applying at least one electrical signal to the electrode via the conductor such that an electromagnetic field emanates from the electrode to at least one of nerves and muscles of the mammal.
    Type: Application
    Filed: December 18, 2008
    Publication date: June 24, 2010
    Applicant: ElectroCore, Inc.
    Inventors: Bruce Simon, Steven Mendez, Hecheng Hu, Richard P. Dickerson, James R. Pastena
  • Publication number: 20100042178
    Abstract: Methods and devices for treating bronchial constriction related to asthma and anaphylaxis wherein the treatment includes providing an electrical impulse to a selected region of the vagus nerve and/or the lungs of a patient suffering from bronchial constriction.
    Type: Application
    Filed: November 1, 2006
    Publication date: February 18, 2010
    Applicant: ElectroCore, Inc.
    Inventors: Joseph Errico, James Pastena, Steven Mendez, Hecheng Hu, Arthur Ross
  • Publication number: 20090281593
    Abstract: Devices, systems and methods for treating bronchial constriction related to asthma, anaphylaxis or chronic obstructive pulmonary disease wherein the treatment includes stimulating selected nerve fibers responsible for smooth muscle dilation at a selected region within a patient's neck, thereby reducing the magnitude of constriction of bronchial smooth muscle.
    Type: Application
    Filed: March 20, 2009
    Publication date: November 12, 2009
    Applicant: ElectroCore, Inc.
    Inventors: Joseph P. Errico, James R. Pastena, Steven Mendez, Hecheng Hu, Arthur Ross, Bruce Simon
  • Publication number: 20090259274
    Abstract: The present invention provides systems, apparatus and methods for selectively applying electrical energy to body tissue. A device is provided having an enclosure within an outer wall formed from an electrically-permeable material to allow for electrical energy to pass from the interior of the enclosure through the outer wall. The device further includes an electrode positioned within the interior of the enclosure and a fluid passage coupled to the enclosure for delivery of an electrically conductive fluid into the interior of the enclosure such that the electrically conductive fluid couples the electrode with the electrically-permeable section of the outer wall. The conductive fluid allows for the passage of electrical energy from the electrode through the fluid and the outer wall of the enclosure for treatment of tissue on or in a patient.
    Type: Application
    Filed: February 27, 2009
    Publication date: October 15, 2009
    Applicant: ElectroCore, Inc.
    Inventors: Bruce Simon, Steven Mendez, Hecheng Hu, Richard P. Dickerson, James R. Pastena, Puyun Guo
  • Publication number: 20090234417
    Abstract: Systems and methods are disclosed for treatment of metabolic disorders such as type 2 diabetes and obesity by stimulation of the small intestine to modulate hormone production. Methods include applying an appropriate signal to a region of the small intestine to modulate hormone production. The method may involve applying a signal to the nerves that innervate the small intestine. Devices for delivering the signal are disclosed.
    Type: Application
    Filed: April 30, 2009
    Publication date: September 17, 2009
    Applicant: ElectroCore, Inc.
    Inventors: James R. Pastena, Joseph P. Errico, Steven Mendez, Hecheng Hu, Bruce Simon
  • Publication number: 20090187231
    Abstract: Devices, systems and methods for treating bronchial constriction related to asthma, anaphylaxis or chronic obstructive pulmonary disease wherein the treatment includes stimulating selected nerve fibers responsible for smooth muscle dilation at a selected region within a patient's neck, thereby reducing the magnitude of constriction of bronchial smooth muscle.
    Type: Application
    Filed: March 20, 2009
    Publication date: July 23, 2009
    Applicant: ElectroCore, Inc.
    Inventors: Joseph P. Errico, James R. Pastena, Steven Mendez, Hecheng Hu, Arthur Ross, Bruce Simon