Patents by Inventor Hector Juarez-Salinas

Hector Juarez-Salinas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of deoxyribose nicotinamide adenine dinucleotide to enhance the specificity of NAD.sup.+ -dependent ligation reactions
    Patent number: 5508179
    Abstract: This invention provides methods and compounds relating to the use of deoxyribose nicotinamide adenine dinucleotide (dNAD.sup.+) analogues in NAD.sup.+ -dependent ligation reactions. The compounds and methods may be used in NAD.sup.+ -dependent ligation reactions generally, and to increase the specificity of NAD.sup.+ -dependent ligation reactions.
    Type: Grant
    Filed: March 18, 1994
    Date of Patent: April 16, 1996
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Robert B. Wallace, Hector Juarez-Salinas, Luis Ugozzoli
  • Use of hydroxylapatite for the analysis and preparation of purified monoclonal antibodies
    Patent number: 4745183
    Abstract: A novel method is disclosed for the purification of monoclonal antibodies from antibodies of the same isotype but different light chain composition which are frequently present in the fluids in which such antibodies are generated. According to the method, the mixture is placed in a hydroxylapatite chromatography column and eluted with a buffer solution in a concentration gradient elution. With the appropriate optimization of system parameters, a separation of antibodies effective for both analytical and preparative purposes is obtained.
    Type: Grant
    Filed: December 3, 1984
    Date of Patent: May 17, 1988
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Sheldon C. Engelhorn, Hector Juarez-Salinas, Gary S. Ott
  • Process for binding IgG to protein A
    Patent number: 4704366
    Abstract: Unusually strong binding of IgG to protein A is achieved by contacting these components in the presence of a medium containing a high concentration of salt. Although such binding is of general utility, a particularly useful application is the purification of monoclonal antibodies from ascites fluid by affinity chromatography.
    Type: Grant
    Filed: June 22, 1984
    Date of Patent: November 3, 1987
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Hector Juarez-Salinas, Gary S. Ott