Abstract: A fiber laser system based in solitonic passive mode-locking, including a laser diode to emit and deliver an optical signal of a first wavelength; a single-fiber laser cavity including a dichroic mirror, a SESAM and a polarization maintaining highly-doped active fiber, to receive the emitted signal and to emit a pulsed optical signal of a second wavelength, generating laser light in the form of mode-locked ultrashort pulses; a unit coupling the laser diode to the single-fiber laser cavity; and an isolator device protecting the cavity from back reflections. The solitonic mode-locked ultrashort pulses are comprised in a range of 100 fs<10 ps with repetition rates of hundreds MHz to tens of GHz.

Abstract: An all-fiber configuration system and method for generating temporally coherent supercontinuum pulsed emission are provided. The system includes a sequential structure of all-fiber sections including: a fiber laser seed source to produce a seed pulse with given optical properties; a stretching section including an optical fiber to temporally stretch the seed pulse; an amplification section including an active optical fiber, doped with a rare earth element, to amplify the stretched pulse by progressively stimulating radiation of active ions of the doped active optical fiber; a compressing section to temporally compress the amplified pulse; and a spectrum broadening section including an ANDi microstructured fiber that spectrally broadens the compressed pulse by a nonlinear effect of Self Phase Modulation (SPM) while maintaining the temporal coherence of the pulse.

Abstract: A fiber laser system based in solitonic passive mode-locking, including a laser diode to emit and deliver an optical signal of a first wavelength; a single-fiber laser cavity including a dichroic mirror, a SESAM and a polarization maintaining highly-doped active fiber, to receive the emitted signal and to emit a pulsed optical signal of a second wavelength, generating laser light in the form of mode-locked ultrashort pulses; a unit coupling the laser diode to the single-fiber laser cavity; and an isolator device protecting the cavity from back reflections. The solitonic mode-locked ultrashort pulses are comprised in a range of 100 fs<10 ps with repetition rates of hundreds MHz to tens of GHz.

Abstract: A fiber laser system based in solitonic passive mode-locking, including a laser diode to emit and deliver an optical signal of a first wavelength; a single-fiber laser cavity including a dichroic mirror, a SESAM and a polarization maintaining highly-doped active fiber, to receive the emitted signal and to emit a pulsed optical signal of a second wavelength, generating laser light in the form of mode-locked ultrashort pulses; a unit coupling the laser diode to the single-fiber laser cavity; and an isolator device protecting the cavity from back reflections. The solitonic mode-locked ultrashort pulses are comprised in a range of 100 fs<10 ps with repetition rates of hundreds MHz to tens of GHz.

Abstract: An automated system communicated to a remote server for diagnostically field testing a sample taken from a patient using an automated portable handheld instrument to determine the presence of Covid-19 and/or antibodies thereto includes microfluidic circuits defined in a rotatable disk for performing a bioassay using a microarray to generate an electrical signal indicative of a bioassay measurement; the microarray operationally positioned in the microfluidic circuit; one or more lasers; one or more positionable valves in the microfluidic circuit; and a backbone unit for rotating the disk according to a protocol to perform the bioassay, for controlling the lasers to selectively open the positionable valves in the microfluidic disk, for operating the microarray to generate a digital image as a bioassay measurement; for communicating the bioassay measurement to the remote server, and for associating the performed bioassay and its corresponding bioassay measurement to the patient.

Abstract: A light inspection system and method of the surface and inside of a sample. The system includes a light source generating a light beam to impinge on a sample; an imaging system obtaining an image of said sample and including a parabolic mirror with a hole to allow the passage of the light beam towards the sample, and the redirection of a scattered light component of the sample towards a light capturing unit comprising a bundle of bifurcated fibers; the bundle of fibers having a central fiber and external fibers, the central fiber receiving scattered light from the surface and the external fibers receiving scattered light from inside the sample; a measuring system measuring a power and/or a spectrum collected in the central and the external fibers.

Abstract: A light inspection system and method of the surface and inside of a sample. The system includes a light source generating a light beam to impinge on a sample; an imaging system obtaining an image of said sample and including a parabolic mirror with a hole to allow the passage of the light beam towards the sample, and the redirection of a scattered light component of the sample towards a light capturing unit comprising a bundle of bifurcated fibers; the bundle of fibers having a central fiber and external fibers, the central fiber receiving scattered light from the surface and the external fibers receiving scattered light from inside the sample; a measuring system measuring a power and/or a spectrum collected in the central and the external fibers.

Abstract: An all-fiber configuration system and method for generating temporally coherent supercontinuum pulsed emission are provided. The system includes a sequential structure of all-fiber sections including: a fiber laser seed source to produce a seed pulse with given optical properties; a stretching section including an optical fiber to temporally stretch the seed pulse; an amplification section including an active optical fiber, doped with a rare earth element, to amplify the stretched pulse by progressively stimulating radiation of active ions of the doped active optical fiber; a compressing section to temporally compress the amplified pulse; and a spectrum broadening section including an ANDi microstructured fiber that spectrally broadens the compressed pulse by a nonlinear effect of Self Phase Modulation (SPM) while maintaining the temporal coherence of the pulse.

Abstract: A fiber laser system based in solitonic passive mode-locking, including a laser diode to emit and deliver an optical signal of a first wavelength; a single-fiber laser cavity including a dichroic mirror, a SESAM and a polarization maintaining highly-doped active fiber, to receive the emitted signal and to emit a pulsed optical signal of a second wavelength, generating laser light in the form of mode-locked ultrashort pulses; a unit coupling the laser diode to the single-fiber laser cavity; and an isolator device protecting the cavity from back reflections. The solitonic mode-locked ultrashort pulses are comprised in a range of 100 fs<10 ps with repetition rates of hundreds MHz to tens of GHz.

Abstract: Dry powder inhalable compositions and methods for using and making the compositions are disclosed for vaccinating a subject against disease. In particular, the compositions are inhalable dry powders useful for preventing and/or treating diseases caused by microorganisms, for example, microorganisms such as viral or bacterial pathogens, including, the influenza virus. In particular, the method comprises the administration of an inhalable composition comprising virus-like particles and/or specific protein/s or antigenic peptides, peptide fragments and/or derivatives thereof using a dry powder drug delivery system.

Abstract: A polyurethane-based composition is disclosed which includes a polyurethane prepolymer, a solvent, a plasticizer and a curing agent, wherein the curing agent contains a mononuclear aromatic polyamine, and is present in an amount such that the molar ratio of all amine functions in the polyamine to all isocyanate functions in the composition is at least 0.7 to 1. Such polyurethane-based compositions have proven effective for example as adhesives and fillers in the repair of elastic substrates since they can be processed quickly and readily even at low temperatures. Methods are also disclosed for bonding or repairing elastic substrates that include corresponding polyurethane-based compositions, and to use of the composition for bonding and repairing elastic substrates.

Abstract: Dry powder inhalable compositions and methods for using and making the compositions are disclosed for vaccinating a subject against disease. In particular, the compositions are inhalable dry powders useful for preventing and/or treating diseases caused by microorganisms, for example, microorganisms such as viral or bacterial pathogens, including, the influenza virus. In particular, the method comprises the administration of an inhalable composition comprising virus-like particles and/or specific protein/s or antigenic peptides, peptide fragments and/or derivatives thereof using a dry powder drug delivery system.