Abstract: The present invention relates to an anti-VAMP2 antibody that inhibits SNARE complex and uses thereof, and more specifically, the present invention relates to an anti-VAMP2 antibody or antigen-binding fragments thereof comprising heavy and light chain CDRs of a specific sequence. The anti-VAMP2 antibody is expected to be useful for improving or treating skin wrinkles by inhibiting SNARE complex formation.

Abstract: The present disclosure relates to an anti-SNAP 25 antibody for inhibiting a SNARE complex, and a use thereof and, more specifically, to an anti-SNAP 25 antibody comprising heavy chain CDRs and light chain CDRs of specific sequences, or an antigen-binding fragment thereof. The anti-snap 25 antibody inhibits the formation of a SNARE complex, and thus is expected to be advantageously used for reducing or treating skin wrinkles.

Abstract: The present invention relates to an anti-DKK-1 antibody promoting growth of human dermal papilla cells and a use thereof and, more particularly, to an anti-DKK-1 antibody comprising a heavy chain CDR and a light chain CDR of specific sequences, and an antigen-binding fragment thereof, wherein the anti-DKK-1 antibody promotes the growth of human dermal papilla cells and as such, is expected to be effectively used for promoting hair growth and preventing, alleviating, or treating hair loss.

Abstract: The present invention relates to an anti-tyrosinase antibody for inhibiting tyrosinase and use thereof, and more particularly, to an anti-tyrosinase antibody including a heavy chain CDR and a light chain CDR of specific sequences, or an antigen-binding fragment thereof. The anti-tyrosinase antibody is expected to be effectively utilized for improving skin whitening or treating skin pigmentation disorders by inhibiting tyrosinase activity.

Abstract: The present invention relates to an anti-VAMP2 antibody that inhibits SNARE complex and uses thereof, and more specifically, the present invention relates to an anti-VAMP2 antibody or antigen-binding fragments thereof comprising heavy and light chain CDRs of a specific sequence. The anti-VAMP2 antibody is expected to be useful for improving or treating skin wrinkles by inhibiting SNARE complex formation.

Abstract: The present invention relates to a method for producing endothelial progenitor cells, comprising a method for producing induced pluripotent stem cells by using only Oct4 and Sox2 as a reprogramming factor of human dental pulp cells, and differentiating endothelial progenitor cells from the induced pluripotent stem cells produced by the method for producing induced pluripotent stem cells. Moreover, the present invention relates to a method for producing endothelial cells, comprising differentiating endothelial cells from endothelial progenitor cells produced by the method for producing the endothelial progenitor cells. Additionally, the present invention relates to a method for producing smooth muscle cells, comprising differentiating smooth muscle cells from endothelial progenitor cells produced by the method for producing the endothelial progenitor cells.