Patents by Inventor Hee Ko

Hee Ko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8324175
    Abstract: The present invention discloses anti-cancer compositions, and associated methods, including an anti-cancer composition comprising: a cellular energy inhibitor having the structure according to formula I wherein X is selected from the group consisting of: a nitro, an imidazole, a halide, sulfonate, a carboxylate, an alkoxide, and amine oxide; and R is selected from the group consisting of: OR?, N(R?)2, C(O)R??, C1-C6 alkyl, C6-C12 aryl, C1-C6 heteroalkyl, a C6-C12 heteroaryl, H, and an alkali metal; where R? represents H, alkali metal, C1-C6 alkyl, C6-C12 aryl or C(O)R??, R? represents H, C1-C6 alkyl, or C6-C12 aryl, and R?? represents H, C1-C20 alkyl or C6-C12 aryl. The anti-cancer composition can additionally comprise at least one sugar, which stabilizes the cellular energy inhibitor by substantially preventing the inhibitor from hydrolyzing. Also, the anti-cancer composition can comprise a hexokinase inhibitor.
    Type: Grant
    Filed: August 3, 2010
    Date of Patent: December 4, 2012
    Inventor: Young Hee Ko
  • Publication number: 20120247979
    Abstract: An electrochemical system with reduced limiting-current behavior is disclosed. The electrochemical system is useful for fuel cells and bio-sensors. In part, the invention relates a method of reducing or eliminating limiting-current behavior in the operation electrochemical systems, in particular those with ion-selective membrane or electrochemical electrodes, by spatially reducing the convection near the membrane or the electrode. The invention further relates to electrochemical systems in which micropores, microarrays or pillar arrays are used to reduce convection in comparison to conventional systems without microarrays, micropores or pillar arrays.
    Type: Application
    Filed: June 17, 2011
    Publication date: October 4, 2012
    Applicant: Massachusetts Institute of Technology
    Inventors: Sung Hee Ko, Sung Jae Kim, Jongyoon Han, HiongYap Gan
  • Patent number: 8259723
    Abstract: A statistical information generator for VoIP traffic analysis is provided, which comprises a packet collection module collecting packets from a network; and a statistical information generation module analyzing information of a call setup packet or a media packet among the packets collected by the packet collection module, and generating statistical information of the network; wherein if the packet collected by the packet collection module is the call setup packet, the statistical information generation module generates the statistical information of the network using at least one of transmitter identification information, receiver identification information, and call identification information among information of the call setup packet as a key value, while if the packet collected by the packet collection module is the media packet, the statistical information generation module generates the statistical information of the network using media session identification information among information of the media p
    Type: Grant
    Filed: December 23, 2009
    Date of Patent: September 4, 2012
    Assignee: Korea Internet & Security Agency
    Inventors: Chang-Yong Lee, Hwan-Kuk Kim, Kyoung-Hee Ko, Hyun-Cheol Jeong
  • Publication number: 20120073349
    Abstract: The present invention relates to a die apparatus which cools metals after hot pressing. More specifically, the present invention relates to an immersion cooling type die apparatus, in which dies are immersed in a coolant to enhance a cooling rate of the dies while guaranteeing uniform quality. The die apparatus includes an upper die having a pressing surface formed on a lower surface thereof, a lower die having a pressing surface formed on an upper surface thereof, a coolant bath storing a predetermined level of coolant, and a pressing unit driven to lower and compress the upper die onto the lower die, to lower both the upper and lower dies in a compressed state, and to lift the upper and lower dies in a reverse sequence.
    Type: Application
    Filed: December 28, 2010
    Publication date: March 29, 2012
    Applicant: Hyundai Steel Company
    Inventor: Kang-Hee Ko
  • Publication number: 20120060218
    Abstract: Provided is a system for blocking session initiation protocol (SIP)-based abnormal traffic. The system includes: a policy database (DB) in which allowed traffic is stored according to transmission priority; an abnormal traffic response module which receives traffic from a first network and transmits only portions of the received traffic, which match the allowed traffic stored in the policy DB, to a second network in order of transmission priority; and an abnormal traffic detection module which analyzes the traffic received from the first network and provides an activation signal to the abnormal traffic response module when detecting that the received traffic is abnormal traffic, wherein the abnormal traffic response module transmits the portions of the received traffic, which match the allowed traffic stored in the policy DB, to the second network such that the sum of the portions transmitted to the second network does not exceed a maximum allowed traffic limit.
    Type: Application
    Filed: November 10, 2010
    Publication date: March 8, 2012
    Inventors: JEONG-WOOK KIM, Hwan-Kuk Kim, Kyoung-Hee Ko, Chang-Yong Lee, Hyun-Cheol Jeong
  • Patent number: 8119116
    Abstract: The present invention relates to methods of treating a cancerous tumor using selective inhibitors of ATP production. The present invention also relates to pharmaceutical preparations comprising such inhibitors and methods for administering them intraarterially directly to a tumor, as well as methods for identifying compositions that selectively inhibitor ATP production for use in the invention.
    Type: Grant
    Filed: January 16, 2009
    Date of Patent: February 21, 2012
    Assignee: John Hopkins University School of Medicine
    Inventors: Young Hee Ko, Jean-Francois Geschwind, Peter L. Pedersen
  • Publication number: 20120036579
    Abstract: Provided is a system for detecting abnormal traffic on a network. The system includes: a receiving module which receives session initiation protocol (SIP) traffic information from a network; a decoding module which receives the SIP traffic information from the receiving module and decodes the received SIP traffic information; a traffic information database (DB) which receives the decoded SIP traffic information from the decoding module and stores the received SIP traffic information; an analysis traffic information DB which collects information from the traffic information DB for a predetermined period and stores the collected information as analysis traffic information; a reference traffic information DB which stores reference traffic information; and an attack detection module which compares the analysis traffic information with the reference traffic information and detects whether analysis traffic is attack traffic.
    Type: Application
    Filed: December 9, 2010
    Publication date: February 9, 2012
    Inventors: Chang-Yong LEE, Hwan-Kuk KIM, Kyoung-Hee KO, Jeong-Wook KIM, Hyun-Cheol JEONG
  • Patent number: 8095852
    Abstract: A data recorder includes a first memory element including read/write capability, a second memory element including non-volatile memory and a controller for realizing memory management functions. The controller responds to a predetermined triggering event by writing selected data from the first memory element to the second memory element. The selected data include data units that have been modified after a prior triggering event.
    Type: Grant
    Filed: August 20, 2010
    Date of Patent: January 10, 2012
    Assignee: Cronera Systems Incorporated
    Inventors: Gwon Hee Ko, John Massie
  • Patent number: 8022042
    Abstract: The present invention discloses anti-cancer compositions, and associated methods, including an anti-cancer composition comprising: a cellular energy inhibitor having the structure according to formula I wherein X is selected from the group consisting of: a nitro, an imidazole, a halide, sulfonate, a carboxylate, an alkoxide, and amine oxide; and R is selected from the group consisting of: OR?, N(R?)2, C(O)R??, C1-C6 alkyl, C6-C12 aryl, C1-C6 heteroalkyl, a C6-C12 heteroaryl, H, and an alkali metal; where R? represents H, alkali metal, C1-C6 alkyl, C6-C12 aryl or C(O)R??, R? represents H, C1-C6 alkyl, or C6-C12 aryl, and R?? represents H, C1-C20 alkyl or C6-C12 aryl. The anti-cancer composition can additionally comprise at least one sugar, which stabilizes the cellular energy inhibitor by substantially preventing the inhibitor from hydrolyzing. Also, the anti-cancer composition can comprise a glycolysis inhibitor.
    Type: Grant
    Filed: January 29, 2010
    Date of Patent: September 20, 2011
    Inventor: Young Hee Ko
  • Publication number: 20110220498
    Abstract: A multiplexed concentration interface that can connect with a plurality of microchannels, conventional 96 well plates or other microarrays is disclosed. The interface can be used in biosensing platforms and can be designed to detect single or multiple targets such as DNA/RNA, proteins and carbohydrates/oligosaccharides. The multiplexed concentration device will provide a set of volume-matched sample preparation and detection strategies directly applicable by ordinary researchers. Furthermore, a multiplexed microfluidic concentrator without buffer channels is disclosed.
    Type: Application
    Filed: December 2, 2010
    Publication date: September 15, 2011
    Applicant: Massachusetts Institute of Technology
    Inventors: Sung Hee Ko, Sung Jae Kim, Jongyoon Han
  • Publication number: 20110138462
    Abstract: Provided is a system for detecting a voice over Internet protocol (VoIP) toll fraud attack. The system includes: a database (DB) storing registration information of normal users; a packet reception module receiving a call set-up packet from a network; and a VoIP signaling message forgery/falsification detection module receiving the call set-up packet from the packet reception module and comparing sender address information or header information of the call set-up packet with the registration information stored in the DB to detect whether the call set-up packet is a packet received from one of the normal users.
    Type: Application
    Filed: December 23, 2009
    Publication date: June 9, 2011
    Inventors: Jeong-Wook Kim, Hwan-Kuk Kim, Hyun-Cheol Jeong, Yoo-Jae Won, Seok-Ung Yoon, Jong-II Jeong, Kyoung-Hee Ko
  • Publication number: 20110058481
    Abstract: A statistical information generator for VoIP traffic analysis is provided, which comprises a packet collection module collecting packets from a network; and a statistical information generation module analyzing information of a call setup packet or a media packet among the packets collected by the packet collection module, and generating statistical information of the network; wherein if the packet collected by the packet collection module is the call setup packet, the statistical information generation module generates the statistical information of the network using at least one of transmitter identification information, receiver identification information, and call identification information among information of the call setup packet as a key value, while if the packet collected by the packet collection module is the media packet, the statistical information generation module generates the statistical information of the network using media session identification information among information of the media p
    Type: Application
    Filed: December 23, 2009
    Publication date: March 10, 2011
    Inventors: CHANG-YONG LEE, Hwan-Kuk Kim, Kyoung-Hee Ko, Hyun-Cheol Jeong
  • Publication number: 20110008418
    Abstract: The present invention discloses anti-cancer compositions, and associated methods, including an anti-cancer composition comprising: a cellular energy inhibitor having the structure according to formula I wherein X is selected from the group consisting of: a nitro, an imidazole, a halide, sulfonate, a carboxylate, an alkoxide, and amine oxide; and R is selected from the group consisting of: OR?, N(R?)2, C(O)R??, C1-C6 alkyl, C6-C12 aryl, C1-C6 heteroalkyl, a C6-C12 heteroaryl, H, and an alkali metal; where R? represents H, alkali metal, C1-C6 alkyl, C6-C12 aryl or C(O)R??, R? represents H, C1-C6 alkyl, or C6-C12 aryl, and R?? represents H, C1-C20 alkyl or C6-C12 aryl. The anti-cancer composition can additionally comprise at least one sugar, which stabilizes the cellular energy inhibitor by substantially preventing the inhibitor from hydrolyzing. Also, the anti-cancer composition can comprise a hexokinase inhibitor.
    Type: Application
    Filed: August 3, 2010
    Publication date: January 13, 2011
    Inventor: Young Hee Ko
  • Publication number: 20100318748
    Abstract: A data recorder includes a first memory element including read/write capability, a second memory element including non-volatile memory and a controller for realizing memory management functions. The controller responds to a predetermined triggering event by writing selected data from the first memory element to the second memory element. The selected data include data units that have been modified after a prior triggering event.
    Type: Application
    Filed: August 20, 2010
    Publication date: December 16, 2010
    Inventors: Gwon Hee Ko, John Massie
  • Publication number: 20100221220
    Abstract: The present invention relates to methods of treating a cancerous tumor using selective inhibitors of ATP production. The present invention also relates to pharmaceutical preparations comprising such inhibitors and methods for administering them intraarterially directly to a tumor, as well as methods for identifying compositions that selectively inhibitor ATP production for use in the invention.
    Type: Application
    Filed: June 15, 2009
    Publication date: September 2, 2010
    Inventor: Young Hee Ko
  • Patent number: 7783956
    Abstract: A data recorder includes a first memory element including read/write capability, a second memory element including non-volatile memory and a controller for realizing memory management functions. The controller responds to a predetermined triggering event by writing selected data from the first memory element to the second memory element. The selected data include data units that have been modified after a prior triggering event.
    Type: Grant
    Filed: July 12, 2006
    Date of Patent: August 24, 2010
    Assignee: Cronera Systems Incorporated
    Inventors: Gwon Hee Ko, John Massie
  • Publication number: 20100197612
    Abstract: The present invention discloses anti-cancer compositions, and associated methods, including an anti-cancer composition comprising: a cellular energy inhibitor having the structure according to formula I wherein X is selected from the group consisting of: a nitro, an imidazole, a halide, sulfonate, a carboxylate, an alkoxide, and amine oxide; and R is selected from the group consisting of: OR?, N(R?)2, C(O)R??, C1-C6 alkyl, C6-C12 aryl, C1-C6 heteroalkyl, a C6-C12 heteroaryl, H, and an alkali metal; where R? represents H, alkali metal, C1-C6 alkyl, C6-C12 aryl or C(O)R??, R? represents H, C1-C6 alkyl, or C6-C12 aryl, and R?? represents H, C1-C20 alkyl or C6-C12 aryl. The anti-cancer composition can additionally comprise at least one sugar, which stabilizes the cellular energy inhibitor by substantially preventing the inhibitor from hydrolyzing. Also, the anti-cancer composition can comprise a glycolysis inhibitor.
    Type: Application
    Filed: January 29, 2010
    Publication date: August 5, 2010
    Inventor: Young Hee Ko
  • Patent number: 7754693
    Abstract: This invention provides compositions and methods for the treatment of cancer. An inhibitor cocktail buffer includes at least one sugar, a non-potassium containing buffer, and an inhibitor having the general formula: Such an inhibitor cocktail buffer allows for the efficacious and safe delivery of various compounds, including halopyruvates and derivatives thereof, to human cancer patients.
    Type: Grant
    Filed: February 14, 2007
    Date of Patent: July 13, 2010
    Inventor: Young Hee Ko
  • Publication number: 20100154057
    Abstract: The present invention relates to a Session Initiation Protocol (SIP) intrusion detection and response architecture for protecting SIP-based services, and more specifically, to an SIP intrusion detection and response architecture for protecting SIP-based services, in which SIP-based attacks of a new type can be coped with by detecting the SIP-based attacks and SIP traffic anomalies and managing an SIP-aware security device without degrading quality of multimedia, and signal and media channels can be examined through an SIP-aware intrusion prevention system (IPS) for the purpose of preventing an attacker from hindering a call through manipulation of an SIP message and session-hijacking among legitimate users and attempting a toll fraud by detouring authentication.
    Type: Application
    Filed: January 14, 2009
    Publication date: June 17, 2010
    Applicant: Korea Information Security Agency
    Inventors: Kyoung Hee KO, Hwan-Kuk Kim, JeongWook Kim, Chang-Yong Lee, HyunCheol Jeong
  • Publication number: 20090326068
    Abstract: The present invention relates to methods of treating a cancerous tumor using selective inhibitors of ATP production. The present invention also relates to pharmaceutical preparations comprising such inhibitors and methods for administering them intraarterially directly to a tumor, as well as methods for identifying compositions that selectively inhibitor ATP production for use in the invention.
    Type: Application
    Filed: January 16, 2009
    Publication date: December 31, 2009
    Applicant: The Johns Hopkins University
    Inventors: Young Hee Ko, Jean-Francois H. Geschwind, Peter L. Pedersen