Abstract: Disclosed herein is a dental anesthetic injection device. The dental anesthetic injection device includes a laser generator, a pressure generator filled with a liquid for generating pressure, which expands due to a laser emitted by the laser generator, an anesthetic container which contains an anesthetic for dental use, a separation film disposed between the pressure generator and the anesthetic container and formed to be elastically deformable to transfer expansion energy of the pressure generator to the anesthetic container, and a replacement nozzle detachably coupled with the anesthetic container to be replaceable depending on an oral environment and configured to jet the anesthetic of the anesthetic container toward an oral cavity.