Abstract: The present invention relates to a pharmaceutical composition for preventing or treating neurodegenerative diseases comprising a COX2 acetylating agent as an active ingredient and, more particularly, to a pharmaceutical composition for preventing or treating neurodegenerative diseases comprising, as an active ingredient, a COX2 acetylating agent which exhibits an effect of inhibiting the deposition of amyloid-? in brain neurons, reducing excessive neuroinflammatory responses, and increasing the phagocytosis of amyloid-? in microglial cells. The pharmaceutical composition for preventing or treating neurodegenerative diseases comprising the COX2 acetylating agent as an active ingredient has the effects of alleviating neuroinflammation by promoting COX2 acetylation in neurons and secreting specialized pro-resolving mediators (SPMs) and thus, can be very useful in the development of a preventive or therapeutic agent for neurodegenerative diseases.

Abstract: A method for designing a magnetic plate allowing magnetic particles contained in magnetic ink distributed at different densities includes estimating a distribution of the magnetic particles allowing the magnetic ink to be spread, estimating forms of magnetic field applying the magnetic force to the magnetic particles in order for the magnetic ink to be spread in a desired magnetic printing pattern within the printing layer, obtaining adjustment factors of the magnetic plate corresponding to the estimated forms of the magnetic field by using a model for which deep learning or machine learning has been performed using design conditions including at least one of an upper surface structure of the magnetic plate and a magnetization property of the magnetic plate and obtaining a parameter for the magnetic plate configured to form the magnetic printing pattern based on the obtained adjustment factors.

Abstract: A magnetic domain drawing apparatus includes a magnetic plate moving module including a magnetic plate seating part configured to hold a magnetic plate seated thereon and a magnetic plate moving part configured to move the magnetic plate seating part, and at least one of magnetic domain deforming modules disposed to be spaced apart from the magnetic plate seating part at a predetermined distance and configured to deform a magnetic domain of the magnetic plate when the magnetic plate is seated on the magnetic plate seating part. The at least one of magnetic domain deforming modules is configured to deform the magnetic domain of the magnetic plate by applying at least one of heat, a magnetic field and an external force to the magnetic plate.

Abstract: The present disclosure provides a skyrmion diode using skyrmions as information carriers. The skyrmion diode includes a magnetic body and a conductive body. The magnetic body has a skyrmion which is used as information carrier. The conductive body is disposed on or under the magnetic body. The conductive body includes a Dzyaloshinskii-Moriya interaction (DMI) region and a defect region. The DMI region is provided to induce DMI in a region of the magnetic body corresponding to the DMI region by the spin-orbit coupling of the conductive body and magnetic moments of the magnetic body. The defect region is provided to prevent the DMI from being induced in a region of the magnetic body corresponding to the defect region.

Abstract: A method for designing a magnetic plate allowing magnetic particles contained in magnetic ink distributed at different densities includes estimating a distribution of the magnetic particles allowing the magnetic ink to be spread, estimating forms of magnetic field applying the magnetic force to the magnetic particles in order for the magnetic ink to be spread in a desired magnetic printing pattern within the printing layer, obtaining adjustment factors of the magnetic plate corresponding to the estimated forms of the magnetic field by using a model for which deep learning or machine learning has been performed using design conditions including at least one of an upper surface structure of the magnetic plate and a magnetization property of the magnetic plate and obtaining a parameter for the magnetic plate configured to form the magnetic printing pattern based on the obtained adjustment factors.

Abstract: A magnetic domain drawing apparatus includes a magnetic plate moving module including a magnetic plate seating part configured to hold a magnetic plate seated thereon and a magnetic plate moving part configured to move the magnetic plate seating part, and at least one of magnetic domain deforming modules disposed to be spaced apart from the magnetic plate seating part at a predetermined distance and configured to deform a magnetic domain of the magnetic plate when the magnetic plate is seated on the magnetic plate seating part. The at least one of magnetic domain deforming modules is configured to deform the magnetic domain of the magnetic plate by applying at least one of heat, a magnetic field and an external force to the magnetic plate.

Abstract: The present disclosure provides a skyrmion diode using skyrmions as information carriers. The skyrmion diode includes a magnetic body and a conductive body. The magnetic body has a skyrmion which is used as information carrier. The conductive body is disposed on or under the magnetic body. The conductive body includes a Dzyaloshinskii-Moriya interaction (DMI) region and a defect region. The DMI region is provided to induce DMI in a region of the magnetic body corresponding to the DMI region by the spin-orbit coupling of the conductive body and magnetic moments of the magnetic body. The defect region is provided to prevent the DMI from being induced in a region of the magnetic body corresponding to the defect region.

Abstract: The present disclosure provides a skyrmion diode using skyrmions as information carriers. The skyrmion diode includes a magnetic body and a conductive body. The magnetic body has a skyrmion which is used as information carrier. The conductive body is disposed on or under the magnetic body. The conductive body includes a Dzyaloshinskii-Moriya interaction (DMI) region and a defect region. The DMI region is provided to induce DMI in a region of the magnetic body corresponding to the DMI region by the spin-orbit coupling of the conductive body and magnetic moments of the magnetic body. The defect region is provided to prevent the DMI from being induced in a region of the magnetic body corresponding to the defect region.

Abstract: The present disclosure provides a skyrmion diode using skyrmions as information carriers. The skyrmion diode includes a magnetic body and a conductive body. The magnetic body has a skyrmion which is used as information carrier. The conductive body is disposed on or under the magnetic body. The conductive body includes a Dzyaloshinskii-Moriya interaction (DMI) region and a defect region. The DMI region is provided to induce DMI in a region of the magnetic body corresponding to the DMI region by the spin-orbit coupling of the conductive body and magnetic moments of the magnetic body. The defect region is provided to prevent the DMI from being induced in a region of the magnetic body corresponding to the defect region.

Abstract: The present invention relates to a method for measuring a ceruloplasmin concentration, and more particularly, to a method for measuring a ceruloplasmin in a blood spot based on a standard concentration curve obtained through an enzyme-linked immunosorbent assay (ELISA) or a dissociation-enhanced time-resolved fluoroimmunoassay using a ceruloplasmin-specific polyclonal antibody or a ceruloplasmin-specific monoclonal antibody.

Abstract: The present invention relates to a method for measuring a ceruloplasmin concentration, and more particularly, to a method for measuring a ceruloplasmin in a blood spot based on a standard concentration curve obtained through an enzyme-linked immunosorbent assay (ELISA) or a dissociation-enhanced time-resolved fluoroimmunoassay using a ceruloplasmin-specific polyclonal antibody or a ceruloplasmin-specific monoclonal antibody.

Abstract: The present invention relates to a method for measuring a holoceruloplasmin concentration, and more particularly, to a method for measuring a holoceruloplasmin in a blood spot based on a standard concentration curve obtained through an enzyme-linked immunosorbent assay (ELISA) or a dissociation-enhanced time-resolved fluoroimmunoassay using a holoceruloplasmin-specific polyclonal antibody and a holoceruloplasmin-specific monoclonal antibody.

Abstract: The present invention relates to a method for measuring a holoceruloplasmin concentration, and more particularly, to a method for measuring a holoceruloplasmin in a blood spot based on a standard concentration curve obtained through an enzyme-linked immunosorbent assay (ELISA) or a dissociation-enhanced time-resolved fluoroimmunoassay using a holoceruloplasmin-specific polyclonal antibody and a holoceruloplasmin-specific monoclonal antibody.