Patents by Inventor Hee Yang

Hee Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250122155
    Abstract: The present invention relates to a compound of Formula 1, a preparation method thereof, a pharmaceutical composition comprising the same as an active ingredient, and a use thereof. The compound of Formula 1 according to the present invention can exhibit cell necrosis and ferroptosis inhibitory efficacy in various cells such as heart, kidney, nerve, retina, liver, or lung cells, and accordingly, can be usefully used for prevention or treatment of cell necrosis or ferroptosis-related diseases.
    Type: Application
    Filed: July 29, 2022
    Publication date: April 17, 2025
    Inventors: Soon Ha Kim, Hye Kyung CHANG, Eun Kyung YOO, Kyung Kuk JANG, Mooyoung SEO, Jin Sung PARK, Jeong-Hee YANG, Hyunjun PARK, Jeong Hyang PARK, Yun Min PARK, Jae Young KIM, Yewon YUN
  • Publication number: 20240269145
    Abstract: The present invention relates to a use of a compound of Chemical Formula 1, an isomer thereof, a solvate thereof, a hydrate thereof, or a pharmaceutically acceptable salt thereof as a ferroptosis inhibitor, and a method of inhibiting ferroptosis using the same. The compound of Chemical Formula 1 according to the present invention may exhibit an effect of inhibiting ferroptosis in various cells such as cardiac, renal, nerve, retinal, hepatic or pulmonary cells, and thus it may be effectively used in preventing or treating a ferroptosis-related disease.
    Type: Application
    Filed: January 25, 2024
    Publication date: August 15, 2024
    Inventors: Soon Ha Kim, Hye Kyung Chang, Mooyoung Seo, Jeong-Hee Yang, Hyunjun Park, Jeong Hyang Park, Yun Min Park, Jin Sung Park, Jae Young Kim, Yewon Yun
  • Publication number: 20240197816
    Abstract: A treatment of rejection of a transplant by a recipient of the transplant is disclosed. Methods for prolonging transplant survival in a recipient of the transplant, prolonging survival of the recipient, delaying and/or suppressing delayed graft function in the recipient, and/or reducing the amount of an immunosuppressant administered for transplantation. The methods include providing the transplant with a CHP or a pharmaceutically acceptable salt thereof is disclosed. Also provided is a method for the production of a pharmaceutical composition for the treatment of a transplant allowing modulating transplant survival in a recipient of the transplant.
    Type: Application
    Filed: December 8, 2023
    Publication date: June 20, 2024
    Applicants: NovMetaPharma Co., Ltd., Seoul National University R&DB Foundation, SEOUL NATIONAL UNIVERSITY HOSPITAL
    Inventors: Seung Hee Yang, Hoeyune Jung, Jong Min Kim, Yon Su Kim, Heonjong Lee
  • Patent number: 11890317
    Abstract: A new use of a cyclo histidine-proline (Cyclo His-Pro, CHP) is disclosed. A composition including cyclo histidine-proline (CHP) as an active ingredient has an excellent protective effect to protect kidney and liver cells from damage and/or toxicity induced by various causes. The composition is useful and effective in protecting kidney and/or liver cells/tissues and in treating a subject with kidney and/or liver diseases and/or damages.
    Type: Grant
    Filed: July 1, 2022
    Date of Patent: February 6, 2024
    Assignee: NovMetaPharma Co., Ltd.
    Inventors: Hoe-Yune Jung, Heon-Jong Lee, Jong-Su Jeon, Yon-Su Kim, Seung-Hee Yang, Yong-Chul Kim, Jong-Joo Moon, Hwan-Soo Yoo, Kyeong-Mi Choi
  • Publication number: 20230386457
    Abstract: Disclosed is a transformer-based voice recognition technology using an improved voice as a conditioning feature. A voice recognition method performed by a voice recognition system may include inputting, to a voice recognition model, clean voice data estimated by a voice improvement model and voice data including noise and performing voice recognition based on the estimated clean voice data and the voice data including the noise by using the voice recognition model. The voice recognition model may be trained to perform the voice recognition robust against noise through a combination of a voice feature of the voice data including the noise and a voice feature of the estimated clean voice data by using the estimated clean voice data as a conditioning feature.
    Type: Application
    Filed: August 9, 2022
    Publication date: November 30, 2023
    Applicant: IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY)
    Inventors: Joon-Hyuk CHANG, Da-Hee YANG
  • Publication number: 20230338295
    Abstract: The present application relates to a solid oral preparation and a preparation method therefor, the preparation comprising granules, which comprise: as an active ingredient, a carbamate compound of chemical formula 1, or a pharmaceutically acceptable salt, an isomer, solvate or a hydrate thereof; a diluent; and a binder.
    Type: Application
    Filed: August 6, 2021
    Publication date: October 26, 2023
    Inventors: Ji Hye LEE, So Young CHOI, Sang Jin KIM, Yun Hee YANG
  • Publication number: 20230343801
    Abstract: An image sensor includes a substrate, a photoelectric conversion region in the substrate with the substrate defining a substrate trench on the photoelectric conversion region, a floating diffusion region adjacent to a side surface of the substrate trench, in the substrate, a gate dielectric film that extends along the side surface and a lower surface of the substrate trench and a transfer gate electrode which includes a lower gate that fills a portion of the substrate trench on the gate dielectric film and has a first width, and an upper gate that has a second width smaller than the first width on the lower gate. The gate dielectric film includes a lower dielectric film interposed between the substrate and the lower gate and has a first thickness, and an upper dielectric film adjacent to the floating diffusion region and has a second thickness greater than the first thickness.
    Type: Application
    Filed: February 8, 2023
    Publication date: October 26, 2023
    Applicant: Samsung Electronics Co., Ltd.
    Inventors: Ju Hee LEE, Dong Mo IM, Ji Hee YANG, Tae-Hun LEE, Ji-Hun LIM
  • Publication number: 20230174046
    Abstract: The present disclosure relates to a hybrid electric vehicle configured to respond to a required torque while reducing exhaust gas emission in a situation where catalyst heating of an engine is not completed, and a driving control method for the hybrid electric vehicle. The driving control method of the hybrid electric vehicle comprises entering catalyst heating control of an engine when there is a request for catalyst heating and a required torque exceeds a first threshold during traveling in a first mode using an electric motor as a driving source, and entering acceleration feeling increase control when the required torque exceeds a second threshold greater than the first threshold, in which the second threshold is set between the first threshold and a third threshold that is a reference for an entry into a second mode using the engine as the driving source.
    Type: Application
    Filed: August 15, 2022
    Publication date: June 8, 2023
    Inventors: Jin Kyeom Cho, Byeong Hee Yang, Seong Wook Moon, Sung Deok Kim
  • Publication number: 20230165855
    Abstract: New uses of Cyclo-HisPro (CHP) or a salt thereof for lowering blood pressure are disclosed. More specifically, the present invention relates to a pharmaceutical composition for lowering blood pressure, containing CHP or a salt thereof, and a functional health food composition containing CHP or a salt thereof; a method for lowering blood pressure using CHP or a salt thereof; a use of CHP or a salt thereof in the manufacture of antihypertensive agents; a pharmaceutical composition or a functional health food, for preventing or treating hypertension or complications thereof, containing CHP or a salt thereof; a method for preventing or treating hypertension or complications thereof by using CHP or a salt thereof; and a use of CHP or a salt thereof in the manufacture of a medicament for preventing or treating hypertension or complications thereof.
    Type: Application
    Filed: March 19, 2021
    Publication date: June 1, 2023
    Applicants: NOVMETAPHARMA CO., LTD., SEOUL NATIONAL UNIVERSITY HOSPITAL, SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Hoe Yune JUNG, Heon Jong LEE, Yon Su KIM, Seung Hee YANG
  • Publication number: 20230071692
    Abstract: A pouch type battery case configured to accommodate an electrode assembly, in which electrodes and separators are stacked, according to an embodiment of the present invention for achieving the above object includes: a first cup part and a second cup part, which are arranged parallel to a pouch film and formed to be recessed; and a bridge formed between the first cup part and the second cup part and having a constant width and height, wherein the first cup part includes: a first outer wall formed toward an opposite to the bridge; a second outer wall formed toward the bridge; and a first bottom portion configured to connect the first outer wall to the second outer wall, and the second cup part includes: a third outer wall formed toward the bridge; a fourth outer wall formed toward the opposite to the bridge; and a second bottom portion configured to connect the third outer wall to the fourth outer wall, wherein the fourth outer wall has a height greater than that of the first outer wall.
    Type: Application
    Filed: October 23, 2020
    Publication date: March 9, 2023
    Applicant: LG Energy Solution, Ltd.
    Inventors: Nan Ji Yun, Hyun Jung Na, Seung Hee Yang, Jin Seo Park
  • Publication number: 20230055621
    Abstract: The present invention relates to a pharmaceutical composition for preventing or treating chronic kidney disease, the composition including graphene quantum dots as an active ingredient. Graphene quantum dots according to the present invention were observed to exhibit the effects of decreasing the expression of fibronectin, collagen 1al, Bax, TGF-?1, Smad2/3, ?-SMA, etc., which are renal fibrosis-related proteins, and increasing the expression of E-cadherin, Smad7, MnSOD, and SOD1, and thereby suppress renal fibrosis. Accordingly, it is expected that the graphene quantum dots according to the present invention will be able to be effectively used in the field of developing agents for treating or alleviating chronic kidney disease caused by renal fibrosis.
    Type: Application
    Filed: November 6, 2020
    Publication date: February 23, 2023
    Inventors: Byung Hee HONG, Jung Pyo LEE, Seung Hee YANG, Lilin LI, Juhee KIM, Donghoon KIM, Jong Bo PARK
  • Patent number: 11530377
    Abstract: The bioenvironmental simulation device according to an embodiment of the present invention includes at least one mounting unit on which cells to be measured are placed, a rotational force application unit configured to rotate the mounting unit so as to apply a rotational force to the cells to be measured placed on the mounting unit, and a culture liquid flow device through which a culture liquid flows across the mounting unit, wherein the culture liquid flows by the culture liquid flow device so as to apply a shear force to the cells to be measured.
    Type: Grant
    Filed: December 10, 2019
    Date of Patent: December 20, 2022
    Assignees: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION, SEOUL NATIONAL UNIVERSITY HOSPITAL
    Inventors: Seung Hee Yang, Yon Su Kim, Dong Ki Kim, Sa Ram Lee, Yong Chul Kim, Mi Yeon Yu, Ji Eun Kim
  • Patent number: 11498575
    Abstract: An unsupervised learning-based detection method according to one technical aspect of the present disclosure relates to an unsupervised learning-based detection method using a supervised-learned model, and includes: generating a first plurality of matrix data on the basis of driving data; generating encoding information by encoding the first plurality of matrix data using a convolutional neural network; modeling a time series feature of the encoding information by using a long short-term memory (LSTM) network, so as to derive a correlation between variables according to a time series; re-implementing a second plurality of matrix data through a deconvolution calculation of the correlation between the variables according to the time series; and determining whether the driving data corresponds to a pre-supervised learned driver profile, on the basis of a difference between the first plurality of matrix data and the second plurality of matrix data.
    Type: Grant
    Filed: November 14, 2019
    Date of Patent: November 15, 2022
    Assignees: Suntech International Ltd.
    Inventor: Seung Hee Yang
  • Patent number: 11484834
    Abstract: Provided is a method for using selective non-catalytic reduction to reduce nitrogen dioxide in exhaust gas generated during an olefin production process. Nitrogen dioxide generated in a catalyst regeneration step of a continuous PDH process can be efficiently removed by the method of the present disclosure. Ultimately, the generation of visible fumes can be prevented through the removal of nitrogen dioxide.
    Type: Grant
    Filed: June 4, 2018
    Date of Patent: November 1, 2022
    Assignees: SK Gas Co., Ltd., Kocat Inc.
    Inventors: Ung Gi Hong, Mi Young Lee, Deuk Soo Park, Jung Ho Kim, Jin Young Kim, Chang Hee Yang
  • Publication number: 20220331396
    Abstract: A new use of a cyclo histidine-proline (Cyclo His-Pro, CHP) is disclosed. A composition including cyclo histidine-proline (CHP) as an active ingredient has an excellent protective effect to protect kidney and liver cells from damage and/or toxicity induced by various causes. The composition is useful and effective in protecting kidney and/or liver cells/tissues and in treating a subject with kidney and/or liver diseases and/or damages.
    Type: Application
    Filed: July 1, 2022
    Publication date: October 20, 2022
    Applicant: NovMetaPharma Co., Ltd.
    Inventors: Hoe-Yune JUNG, Heon-Jong LEE, Jong-Su JEON, Yon-Su KIM, Seung-Hee YANG, Yong-Chul KIM, Jong-Joo MOON, Hwan-Soo YOO, Kyeong-Mi CHOI
  • Patent number: 11433114
    Abstract: A new use of a cyclo histidine-proline (Cyclo His-Pro, CHP) is disclosed. A composition including cyclo histidine-proline (CHP) as an active ingredient has an excellent protective effect to protect kidney and liver cells from damage and/or toxicity induced by various causes. The composition is useful and effective in protecting kidney and/or liver cells/tissues and in treating a subject with kidney and/or liver diseases and/or damages.
    Type: Grant
    Filed: February 10, 2021
    Date of Patent: September 6, 2022
    Assignee: NovMetaPharma Co., Ltd.
    Inventors: Hoe-Yune Jung, Heon-Jong Lee, Jong-Su Jeon, Yon-Su Kim, Seung-Hee Yang, Yong-Chul Kim, Jong-Joo Moon, Hwan-Soo Yoo, Kyeong-Mi Choi
  • Publication number: 20220202897
    Abstract: A Cyclo (his-pro) (CHP) is useful for preventing, ameliorating, or treating fibrosis. A pharmaceutical composition containing CHP may be used for preventing or treating fibrosis. A health functional food composition containing CHP may be used for preventing or ameliorating fibrosis. An antifibrotic composition, a method of preventing, ameliorating, or treating fibrosis by using CHP, and/or a use of CHP in the manufacture of the pharmaceutical composition for preventing or treating fibrosis are disclosed.
    Type: Application
    Filed: March 30, 2020
    Publication date: June 30, 2022
    Applicants: NOVMETAPHARMA CO., LTD., SEOUL NATIONAL UNIVERSITY HOSPITAL, SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Hoe Yune JUNG, Heon Jong LEE, Jong Su JEON, Do Hyun LEE, Yon Su KIM, Seung Hee YANG, Yong Chul KIM, Jong Joo MOON, Ji Eun KIM
  • Publication number: 20220193179
    Abstract: A cyclo(His-Pro)(CHP) is useful for preventing, alleviating or treating peritoneal fibrosis. A pharmaceutical composition for preventing or treating peritoneal fibrosis, a dietary supplement composition for preventing or alleviating peritoneal fibrosis, and a peritoneal dialysis solution, which all contain CHP is disclosed. Also disclosed are a method for preventing or treating peritoneal fibrosis by using CHP, a peritoneal dialysis method using CHP, a use of CHP during the preparation of a pharmaceutical composition for preventing or treating peritoneal fibrosis, and/or a use of CHP in the preparation of a peritoneal dialysis solution.
    Type: Application
    Filed: March 30, 2020
    Publication date: June 23, 2022
    Applicants: NOVMETAPHARMA CO., LTD., SEOUL NATIONAL UNIVERSITY HOSPITAL, SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Hoe Yune JUNG, Do Hyun LEE, Heon Jong LEE, Yon Su KIM, Seung Hee YANG
  • Patent number: 11230740
    Abstract: An apoptosis regulatory gene is detected in an irradiated-thymic lymphoma cell by a method for detecting such an apoptosis regulatory gene in a low-dose-rate and low-level-irradiated thymic lymphoma cell of a mouse. This has an effect of revealing the function of an apoptosis regulatory gene by means of irradiation and providing a gene profile, by detecting an apoptosis regulatory gene detected in an irradiated-thymic lymphoma cell. The detected apoptosis regulatory gene is used to construct a gene profile that can assess the dose-response relationship of industrial and healthcare workers living in a low level-radiation environment. The detected apoptosis regulatory gene can be used as an index for evaluating the extent of cancer progression and the degree of treatment in patients with thymic lymphoma. The method for detecting such an apoptosis regulatory gene is used to prepare a composition for diagnosing thymic lymphoma and a diagnostic kit.
    Type: Grant
    Filed: September 8, 2016
    Date of Patent: January 25, 2022
    Assignee: KOREA HYDRO & NUCLEAR POWER CO., LTD.
    Inventors: Hee Sun Kim, Hoon Choi, Kwang Hee Yang, Yun-Mi Baek, Dong-Kwon Keum, Hee Youn Shim, Byulnim Hwang
  • Patent number: D956095
    Type: Grant
    Filed: February 22, 2021
    Date of Patent: June 28, 2022
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Yeong-Seo Hong, Sul-Hee Yang