Abstract: The present invention relates to a cancer-specific trans-splicing ribozyme as a gene therapy product combined with radiotherapy. The ribozyme of the present disclosure is safe because of the cancer tissue-specific expression thereof and exhibits high expression efficiency at a post-transcriptional level and thus can be provided as a safe and effective gene therapy product. When administered after radiotherapy, the ribozyme exhibits high anticancer effects even at a low dose of radiation and a low dose of gene therapy product and thus is expected to be used in a cancer therapy method and a radiation-resistant cancer therapy method with no or little adverse effects.

Abstract: A particle filtration device according to an embodiment of the present invention as a particle filtration device of a lab-on-disk of a rotation type includes: a filtration film that separates particles by filtering a sample; a main chamber connected to the inlet surface of the filtration film and supplying the sample to the inlet surface of the filtration film; an outlet chamber that is connected to the outlet surface of the filtration film and accommodates the filtration fluid from which particles are separated while passing through the filtration film; and a waste fluid chamber connected to the outlet chamber and storing the filtration fluid, wherein the particle filtration device includes a first flow path that connects between the outlet chamber and the waste fluid chamber, and a second flow path that connects between the outlet chamber and the waste fluid chamber but is positioned farther from the center of the lab-on-disk than the first flow path.

Abstract: The present embodiments relate to a fluid control device using centrifugal force. The fluid control device using centrifugal force includes a fluid control portion comprising a plurality of chambers and controlling a movement of a fluid inside the chamber; a lower fixing portion positioned on a lower portion of the fluid control portion and fixing the plurality of chambers; an upper fixing portion positioned an on upper portion of the fluid control portion and fixing the plurality of chambers; and a fastening member penetrating and fastening the lower fixing portion, the fluid control portion, and the upper fixing portion, wherein the plurality of chambers are disposed to face each other and placed on the lower fixing portion.

Abstract: The present exemplary embodiments provide a chamber for a centrifugal separator and a centrifugal separator including the same. A chamber for a centrifugal separator according to an exemplary embodiment includes a main body including a separation unit in which each component of a centrifuged sample is separated and positioned and an extraction unit configured to move and accommodate each component positioned in the separation unit, an upper plate including an injection port for injecting a sample for centrifugation and a draw-out port for drawing out the separated component that is accommodated in the extraction unit to the outside, and a lower plate configured to close and seal an opening at a lower portion of the main body.

Abstract: A system for inducing respiration according to one embodiment of the present invention comprises: an imaging unit for picking a respiration image of a patient; a respiration signal conversion unit for obtaining a respiration signal of the patient by image processing, and tracking and analyzing the respiration image of the patient obtained from the imaging unit; and a respiration determination unit for determining one or more of whether the obtained respiration signal is suitable for radiation treatment, whether the obtained respiration signal is stable, and whether a matching score between the respiration signal of the patient and a guide respiration is greater than a predetermined reference value; and a respiration guide unit for providing the respiration signal of the patient, obtained from the respiration signal conversion unit, together with a stored guide signal.

Abstract: A quality assurance system for radiation therapy equipment includes an image capturing unit installed on radiation therapy equipment and capturing an image of an indicating part indicating an operational state of the radiation therapy equipment, an image processing unit extracting an edge of the indicating part in image captured by the image capturing unit, a center point extraction unit extracting a center point with respect to the edge, and a quality evaluation unit evaluating quality of the radiation therapy equipment by tracking movement of the center point.

Abstract: A quality assurance system for radiation therapy equipment includes an image capturing unit installed on radiation therapy equipment and capturing an image of an indicating part indicating an operational state of the radiation therapy equipment, an image processing unit extracting an edge of the indicating part in image captured by the image capturing unit, a center point extraction unit extracting a center point with respect to the edge, and a quality evaluation unit evaluating quality of the radiation therapy equipment by tracking movement of the center point.

Abstract: A system for inducing respiration according to one embodiment of the present invention comprises: an imaging unit for picking a respiration image of a patient; a respiration signal conversion unit for obtaining a respiration signal of the patient by image processing, and tracking and analyzing the respiration image of the patient obtained from the imaging unit; and a respiration determination unit for determining one or more of whether the obtained respiration signal is suitable for radiation treatment, whether the obtained respiration signal is stable, and whether a matching score between the respiration signal of the patient and a guide respiration is greater than a predetermined reference value; and a respiration guide unit for providing the respiration signal of the patient, obtained from the respiration signal conversion unit, together with a stored guide signal.

Abstract: The present invention relates to a fiducial marker comprising barium sulfate (BaSO4), a solvent, and a polyethylene glycol-poly(aminourethaneurea) multi-block copolymer, as active ingredients. The fiducial marker of the present invention has an effect of significantly remedying disadvantages of image distortion and dose distortion, which are involved in the gold inner marker used in the conventional art. The fiducial marker of the present invention has very limited in vivo mobility, and thus the fiducial marker is maintained at the position at which it has been initially injected. Since the fiducial marker of the present invention is maintained in a sol or liquid state before in vivo injection, and transited into a gel or solid phase after in vivo injection, the injectability of the fiducial marker by an injector syringe is favorable, and the state of the fiducial marker can be controlled into a phase suitable to each site of the therapeutic target.

Abstract: A quality assurance system for radiation therapy equipment includes an image capturing unit installed on radiation therapy equipment and capturing an image of an indicating part indicating an operational state of the radiation therapy equipment, an image processing unit extracting an edge of the indicating part in image captured by the image capturing unit, a center point extraction unit extracting a center point with respect to the edge, and a quality evaluation unit evaluating quality of the radiation therapy equipment by tracking movement of the center point.

Abstract: The present invention relates to a fiducial marker comprising barium sulfate (BaSO4), a solvent, and a polyethylene glycol-poly(aminourethaneurea) multi-block copolymer, as active ingredients. The fiducial marker of the present invention has an effect of significantly remedying disadvantages of image distortion and dose distortion, which are involved in the gold inner marker used in the conventional art. The fiducial marker of the present invention has very limited in vivo mobility, and thus the fiducial marker is maintained at the position at which it has been initially injected. Since the fiducial marker of the present invention is maintained in a sol or liquid state before in vivo injection, and transited into a gel or solid phase after in vivo injection, the injectability of the fiducial marker by an injector syringe is favorable, and the state of the fiducial marker can be controlled into a phase suitable to each site of the therapeutic target.

Abstract: A method of reserving access to a shared communication link by a number of devices is disclosed, having the steps of: (1) assigning a plurality, m, of counters to each of the number of devices, each counter counting from a first count value to a second count value; (2) using the values within the counting range from the first count value to the second count value to uniquely identify each of the number of devices; and (3) pausing the counting operation of a first counter of the plurality of counters, in each of the number of devices, that has the count value identifying a first of the number of devices requesting access to the shared communication link. Also disclosed, is an apparatus that supports the above-described method.

Abstract: A method of reserving access to a shared communication link by a number of devices is disclosed, having the steps of: (1) assigning a plurality, m, of counters to each of the number of devices, each counter counting from a first count value to a second count value; (2) using the values within the counting range from the first count value to the second count value to uniquely identify each of the number of devices; and (3) pausing the counting operation of a first counter of the plurality of counters, in each of the number of devices, that has the count value identifying a first of the number of devices requesting access to the shared communication link. Also disclosed, is an apparatus that supports the above-described method.