Patents by Inventor Hei-Nga CHAN

Hei-Nga CHAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Magnetic platform for direct and multiplex immune-based detection of trace amount of protein biomarkers
    Patent number: 10739336
    Abstract: The present invention discloses a magnetic platform for direct and multiplex immune-based detection of trace amount of protein biomarkers for cancers, neurodegenerative disease such as Alzheimer's disease
    Type: Grant
    Filed: September 27, 2016
    Date of Patent: August 11, 2020
    Assignee: Hong Kong Baptist University
    Inventors: See Lok Ho, Hei Nga Chan, Di Xu, Hung Wing Li, Ricky Man Shing Wong
  • Imaging beta-amyloid peptides aggregation
    Patent number: 9795694
    Abstract: The present invention is in the field of pharmaceuticals and chemical industries. In particular, one aspect of the present invention relates to methods for labeling, imaging and detecting the beta-amyloid (A?) peptides, oligomers, and fibrils in vitro and in vivo via magnetic resonance and florescence imaging by using modified carbazole-based fluorophores. A further aspect of the present invention relates to a method of reducing and preventing aggregation of beta-amyloid peptides for Alzheimer's disease (AD) as well as of treating and/or preventing Alzheimer's disease by using the modified carbazole-based fluorophore. The modified carbazole-based fluorophore according to an embodiment of the present invention is prepared by conjugating a carbazole-based fluorophore with magnetic nanoparticles to form a conjugate which is permeable to blood brain barrier of a subject being introduced therewith.
    Type: Grant
    Filed: February 21, 2016
    Date of Patent: October 24, 2017
    Assignee: Hong Kong Baptist University
    Inventors: Yinhui Li, Di Xu, See-Lok Ho, Chung-Yan Poon, Hei-Nga Chan, Hung Wing Li, Ricky M. S. Wong
  • Magnetic platform for direct and multiplex immune-based detection of trace amount of protein biomarkers
    Publication number: 20170097340
    Abstract: The present invention discloses a magnetic platform for direct and multiplex immune-based detection of trace amount of protein biomarkers for cancers, neurodegenerative disease such as Alzheimer's disease
    Type: Application
    Filed: September 27, 2016
    Publication date: April 6, 2017
    Inventors: See Lok HO, Hei Nga CHAN, Di XU, Hung Wing LI, Ricky Man Shing WONG
  • Imaging Beta-Amyloid Peptides Aggregation
    Publication number: 20160243264
    Abstract: The present invention is in the field of pharmaceuticals and chemical industries. In particular, one aspect of the present invention relates to methods for labeling, imaging and detecting the beta-amyloid (A?) peptides, oligomers, and fibrils in vitro and in vivo via magnetic resonance and florescence imaging by using modified carbazole-based fluorophores. A further aspect of the present invention relates to a method of reducing and preventing aggregation of beta-amyloid peptides for Alzheimer's disease (AD) as well as of treating and/or preventing Alzheimer's disease by using the modified carbazole-based fluorophore. The modified carbazole-based fluorophore according to an embodiment of the present invention is prepared by conjugating a carbazole-based fluorophore with magnetic nanoparticles to form a conjugate which is permeable to blood brain barrier of a subject being introduced therewith.
    Type: Application
    Filed: February 21, 2016
    Publication date: August 25, 2016
    Inventors: Yinhui LI, Di XU, See-Lok HO, Chung-Yan POON, Hei-Nga CHAN, Hung Wing LI, Ricky M. S. WONG