Patents by Inventor Heidi E. Johnson

Heidi E. Johnson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for discrimination between cytosine and modifications thereof, and for methylome analysis
    Patent number: 9896726
    Abstract: Compositions and methods are provided for discrimination between cytosine and modifications thereof using cytidine deaminases and/or oxygenases. Variants of wild type cytidine deaminases are described which show reduced bias with respect to adjacent nucleotides upstream of the cytosine. The methods provide a rapid and convenient use of enzymes to obtain methylomes.
    Type: Grant
    Filed: July 22, 2015
    Date of Patent: February 20, 2018
    Assignee: New England Biolabs, Inc.
    Inventors: Romualdas Vaisvila, Heidi E. Johnson, Saulius Vainauskas, Theodore B. Davis
  • Methods and Compositions for Discrimination Between Cytosine and Modifications Thereof, and for Methylome Analysis
    Publication number: 20150322506
    Abstract: Compositions and methods are provided for discrimination between cytosine and modifications thereof using cytidine deaminases and/or oxygenases. Variants of wild type cytidine deaminases are described which show reduced bias with respect to adjacent nucleotides upstream of the cytosine. The methods provide a rapid and convenient use of enzymes to obtain methylomes.
    Type: Application
    Filed: July 22, 2015
    Publication date: November 12, 2015
    Applicant: NEW ENGLAND BIOLABS, INC.
    Inventors: Romualdas Vaisvila, Heidi E. Johnson, Saulius Vainauskas, Theodore B. Davis