Abstract: Methods and apparatuses for improving the accuracy of analyte concentration measurements at alternative sites and information provided to the user. The present invention advantageously utilizes information relating to the rate of change of analyte concentrations to adjust analyte concentrations measurements and/or information provided to the user. Therefore, the present invention provides new and improved methods and apparatuses for obtaining analyte concentration information at physiological sites other than the fingertips while ensuring that the analyte concentration information accurately reflects systemic analyte concentration values.

Abstract: Herein is described a system that includes a processing circuit for identifying possible zone D errors among estimated blood glucose concentration values. The system converts estimated blood glucose concentration values which are identified as possible zone D errors into adjusted blood glucose concentration values which are lower in blood glucose concentration magnitude than their corresponding estimated blood glucose concentration values, thereby decreasing the occurrence of zone D errors. Herein is also disclosed a method for improving the clinical accuracy of an analyte concentration measurement. One method includes a first act of computing an estimated analyte concentration having an associated first error that is clinically significant and a second act of processing the estimated analyte concentration to generate an adjusted analyte concentration having a second error that is clinically insignificant.