Patents by Inventor Heidi Trusheim
Heidi Trusheim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240050553Abstract: Currently, the steps performed prior to release of influenza strains to vaccine manufacturers involve passaging influenza virus through eggs. The invention aims to provide procedures useful in manufacturing influenza vaccines, in which the use of eggs is reduced, and preferably is avoided altogether. For instance, rather than use chicken eggs for influenza vaccine isolation, MDCK cells (Madin Darby canine kidney cells) may be used e.g. growing in suspension, growing in a serum-free medium, growing in a protein-free medium, being non-tumorigenic, grown in the absence of an overlay medium, etc.Type: ApplicationFiled: September 25, 2023Publication date: February 15, 2024Applicant: Seqirus UK LimitedInventors: Theodore F. TSAI, Heidi TRUSHEIM
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Publication number: 20200155666Abstract: New influenza donor strains for the production of reassortant influenza A viruses are provided.Type: ApplicationFiled: October 28, 2019Publication date: May 21, 2020Applicants: Synthetic Genomics, Inc.Inventors: Peter MASON, Philip Ralph DORMITZER, Heidi TRUSHEIM, Pirada SUPHAPHIPHAT
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Publication number: 20200000909Abstract: New influenza donor strains for the production of reassortant influenza A viruses are provided.Type: ApplicationFiled: February 11, 2019Publication date: January 2, 2020Applicant: Seqirus UK LimitedInventors: Pirada SUPHAPHIPHAT, Peter MASON, Bjoern KEINER, Philip DORMITZER, Heidi TRUSHEIM
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Patent number: 10500266Abstract: New influenza donor strains for the production of reassortant influenza A viruses are provided.Type: GrantFiled: June 13, 2017Date of Patent: December 10, 2019Assignees: Seqirus UK Limited, Synthetic Genomics, Inc.Inventors: Peter Mason, Philip Ralph Dormitzer, Heidi Trusheim, Pirada Suphaphiphat
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Patent number: 10245312Abstract: New influenza donor strains for the production of reassortant influenza A viruses are provided.Type: GrantFiled: July 14, 2016Date of Patent: April 2, 2019Assignee: Seqirus UK LimitedInventors: Pirada Suphaphiphat, Peter Mason, Bjoern Keiner, Philip Dormitzer, Heidi Trusheim
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Publication number: 20170326227Abstract: New influenza donor strains for the production of reassortant influenza A viruses are provided.Type: ApplicationFiled: June 13, 2017Publication date: November 16, 2017Applicants: Seqirus UK Limited, Synthetic Genomics Vaccines, Inc.Inventors: Peter MASON, Philip Ralph DORMITZER, Heidi TRUSHEIM, Pirada SUPHAPHIPHAT
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Patent number: 9708585Abstract: New influenza donor strains for the production of reassortant influenza A viruses are provided.Type: GrantFiled: December 2, 2013Date of Patent: July 18, 2017Assignee: Seqirus UK LimitedInventors: Peter Mason, Philip Ralph Dormitzer, Heidi Trusheim, Pirada Suphaphiphat
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Publication number: 20170095549Abstract: New influenza donor strains for the production of reassortant influenza A viruses are provided.Type: ApplicationFiled: July 14, 2016Publication date: April 6, 2017Inventors: Pirada SUPHAPHIPHAT, Peter MASON, Bjoern KEINER, Philip DORMITZER, Heidi TRUSHEIM
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Patent number: 9574181Abstract: Methods for producing reassortant viruses are provided wherein the transcription and/or translation of the hemagglutinin and/or neuraminidase genes are suppressed.Type: GrantFiled: October 24, 2014Date of Patent: February 21, 2017Assignee: Seqirus UK LimitedInventors: Heidi Trusheim, Peter Mason, Michael Franti, Björn Keiner, Melissa Sackal, Juerg Hunziker, David Morrissey, François Jean-Charles Natt
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Patent number: 9422528Abstract: New influenza donor strains for the production of reassortant influenza A viruses are provided.Type: GrantFiled: June 3, 2013Date of Patent: August 23, 2016Assignee: Novartis AGInventors: Pirada Suphaphiphat, Peter Mason, Bjoern Keiner, Philip Dormitzer, Heidi Trusheim
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Publication number: 20160193321Abstract: Currently, the steps performed prior to release of influenza strains to vaccine manufacturers involve passaging influenza virus through eggs. The invention aims to provide procedures useful in manufacturing influenza vaccines, in which the use of eggs is reduced, and preferably is avoided altogether. For instance, rather than use chicken eggs for influenza vaccine isolation, MDCK cells (Madin Darby canine kidney cells) may be used e.g. growing in suspension, growing in a serum-free medium, growing in a protein-free medium, being non-tumorigenic, grown in the absence of an overlay medium, etc.Type: ApplicationFiled: November 5, 2015Publication date: July 7, 2016Applicant: Novartis AGInventors: Theodore F. TSAI, Heidi TRUSHEIM
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Publication number: 20150315548Abstract: New influenza donor strains for the production of reassortant influenza A viruses are provided.Type: ApplicationFiled: December 2, 2013Publication date: November 5, 2015Applicants: Novartis AG, Synthetic Genomics Vaccines, Inc.Inventors: Peter MASON, Philip Ralph DORMITZER, Heidi TRUSHEIM, Pirada SUPHAPHIPHAT
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Publication number: 20150161359Abstract: The invention provides improved methods for the safety testing of compositions which comprise biological products produced in a host cell, such as vaccine antigens or recombinant proteins.Type: ApplicationFiled: May 31, 2013Publication date: June 11, 2015Inventors: Heidi Trusheim, Linda Rathaj Hammer, Reinhard Wilms, Walter Hoyer
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Publication number: 20150118746Abstract: Methods for producing reassortant viruses are provided wherein the transcription and/or translation of the hemagglutinin and/or neuraminidase genes are suppressed.Type: ApplicationFiled: October 24, 2014Publication date: April 30, 2015Inventors: Heidi TRUSHEIM, Peter MASON, Michael FRANTI, Björn KEINER, Melissa SACKAL, Juerg HUNZIKER, David MORRISSEY, François Jean-Charles NATT
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Patent number: 8945904Abstract: Methods for producing reassortant viruses are provided wherein the transcription and/or translation of the hemagglutinin and/or neuraminidase genes are suppressed.Type: GrantFiled: May 20, 2011Date of Patent: February 3, 2015Assignee: Novartis AGInventors: Heidi Trusheim, Peter Mason, Michael Franti, Bjoern Keiner, Melissa Sackal, Juerg Hunziker, Francois Natt, David Morrissey
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Publication number: 20140030291Abstract: New influenza donor strains for the production of reassortant influenza A viruses are provided.Type: ApplicationFiled: June 3, 2013Publication date: January 30, 2014Applicant: Novartis AGInventors: Pirada SUPHAPHIPHAT, Peter MASON, Bjoern KEINER, Philip DORMITZER, Heidi TRUSHEIM
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Publication number: 20130216573Abstract: Methods for producing reassortant viruses are provided wherein the transcription and/or translation of the hemagglutinin and/or neuraminidase genes are suppressed.Type: ApplicationFiled: May 20, 2011Publication date: August 22, 2013Applicant: NOVARTIS AGInventors: Heidi Trusheim, Peter Mason, Michael Franti, Bjoern Keiner, Melissa Sackal, Juerg Hunziker, Francois Natt, David Morrissey
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Publication number: 20100010199Abstract: Currently, the steps performed prior to release of influenza strains to vaccine manufacturers involve passaging influenza virus through eggs. The invention aims to provide procedures useful in manufacturing influenza vaccines, in which the use of eggs is reduced, and preferably is avoided altogether. For instance, rather than use chicken eggs for influenza vaccine isolation, MDCK cells (Madin Darby canine kidney cells) may be used e.g. growing in suspension, growing in a serum-free medium, growing in a protein-free medium, being non-tumorigenic, grown in the absence of an overlay medium, etc.Type: ApplicationFiled: September 11, 2007Publication date: January 14, 2010Applicant: NOVARTIS AGInventors: Theodore F. Tsai, Heidi Trusheim
