Patents by Inventor Heike BRUSER

Heike BRUSER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180105838
    Abstract: The invention relates to microbial terpene production. Known methods for microbial production of terpenes are mostly based on the direct conversion of sugars. Therefore alternative substrates, in particular alternative carbon sources, for use in microbial terpene production were desirable. The invention relates to a methylotrophic bacterium containing recombinant DNA coding for at least one polypeptide with enzymatic activity for heterologous expression in said bacterium, wherein said at least one polypeptide with enzymatic activity is selected from the group consisting an enzyme of a heterologous mevalonate pathway, a heterologous terpene synthase and optionally a heterologous synthase of a prenyl diphosphate precursor. The invention further relates in particular to a method for de novo microbial synthesis of sesquiterpenes or diterpenes from methanol and/or ethanol.
    Type: Application
    Filed: March 11, 2016
    Publication date: April 19, 2018
    Inventors: Jens SCHRADER, Markus BUCHHAUPT, Frank SONNTAG, Cora KRONER, Heike BRÜSER, Hartwig SCHRÖDER, Ralf PELZER
  • Publication number: 20170223968
    Abstract: The present invention relates to novel isolated bacterial strains, which are members of the genus Paenibacillus, originally isolated from soil and showing antagonistic activity against a broad range of pathogens and being capable of producing antimicrobial metabolites. It was found that the strains Lu16774 and Lu17007 belong to a novel subspecies named Paenibacillus polymyxa ssp. plantarum while the strain Lu17015 belongs to a novel species which is proposed to be Paenibacillus epiphyticus. The present invention also relates to microbial pesticide compositions comprising at least one of such novel bacterial strains, whole culture broth or a cell-free extract or a fraction thereof or at least one metabolite thereof, and/or a mutant of at least one of said novel bacterial strains having all the identifying characteristics of the respective bacterial strain or whole culture broth, cell-free extract, fraction and/or metabolite of the mutant thereof showing antagonistic activity against plant pathogens.
    Type: Application
    Filed: August 4, 2015
    Publication date: August 10, 2017
    Inventors: Isabella SIEPE, Heike BRUSER, Kristin KLAPPACH, Karl-Heinrich SCHNEIDER, Petra SPROTE, Kerstin HAGE, Birgit BLANZ, Eckhard THINES, Luis ANTELO, Louis Pergaud SANDJO, Till OPATZ
  • Patent number: 9481719
    Abstract: The present invention relates to repetitive self-assembling precursor proteins, nucleic acid sequences and expression constructs encoding the same, and to methods for recombinant production of peptides using such precursor proteins.
    Type: Grant
    Filed: June 2, 2010
    Date of Patent: November 1, 2016
    Assignee: BASF SE
    Inventors: Daniel Hümmerich, Burghard Liebmann, Marcus Fehr, Carsten Schwalb, Heike Brüser
  • Patent number: 8765688
    Abstract: The present invention relates to the use of special peptides in composition which can be used in particular in hair and skin cosmetics, and to such peptide-containing compositions. In particular, the present invention relates to the use of such peptides as active ingredient for inhibition or treatment of dandruff which does not accumulate in the body or in the environment. Furthermore, the invention relates to the production of such compositions, to the peptides used themselves, to their production and to coding nucleotide sequences for such peptides, to dispensing systems for such peptides and to screening methods for identifying suitable further peptides.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: July 1, 2014
    Assignee: BASF SE
    Inventors: Burghard Liebmann, Heike Brüser, Heiko Barg, Daniel Hümmerich, Hubertus Peter Bell
  • Publication number: 20120088268
    Abstract: The present invention relates to repetitive self-assembling precursor proteins, nucleic acid sequences and expression constructs encoding the same, and to methods for recombinant production of peptides using such precursor proteins.
    Type: Application
    Filed: June 2, 2010
    Publication date: April 12, 2012
    Applicant: BASF SE
    Inventors: Daniel Hümmerich, Burghard Liebmann, Marcus Fehr, Carsten Schwalb, Heike Brüser
  • Publication number: 20120065126
    Abstract: The invention relates to a pharmaceutical composition containing, in a pharmaceutical carrier, a peptide comprising at least one sequence motif of the following general formula (I) Hel1-HB-Hel2. The invention also relates to the use and production of said pharmaceutical compositions.
    Type: Application
    Filed: May 12, 2010
    Publication date: March 15, 2012
    Applicant: BASF SE
    Inventors: Heike Brüser, Daniel Hümmerich, Claus Bollschweiler, Carsten Schwalb
  • Publication number: 20100310644
    Abstract: The present invention relates to the use of special peptides in composition which can be used in particular in hair and skin cosmetics, and to such peptide-containing compositions. In particular, the present invention relates to the use of such peptides as active ingredient for inhibition or treatment of dandruff which does not accumulate in the body or in the environment. Furthermore, the invention relates to the production of such compositions, to the peptides used themselves, to their production and to coding nucleotide sequences for such peptides, to dispensing systems for such peptides and to screening methods for identifying suitable further peptides.
    Type: Application
    Filed: December 19, 2008
    Publication date: December 9, 2010
    Applicant: BASF ,Trademarks and Licenses
    Inventors: Burghard Liebmann, Heike Brüser, Heiko Barg, Daniel Hümmerich, Hubertus Peter Bell