Patents by Inventor Heike Rupp

Heike Rupp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11247175
    Abstract: A thermally sterilizable fluid filter (10) for concentrating substances contained in a fluid by way of micro-, nano- or ultrafiltration of the fluid, particularly for concentrating a pharmaceutical precursor and/or intermediate, in particular a vaccine, in a fluid. The fluid filter has a filter housing with a fluid inlet, a retentate outlet and a permeate outlet. A filter cartridge is arranged in the filter housing (12) and has a filter medium of a ceramic material and/or a ceramic composite material. The filter cartridge is held with axial play on the filter housing.
    Type: Grant
    Filed: October 7, 2019
    Date of Patent: February 15, 2022
    Assignee: MANN+HUMMEL GmbH
    Inventors: Heike Rupp, Michael Fasold, Herbert Jainek, Sascha Bauer, Frank Ehlen, Stefan Kunze, Jasmin Sorg, Karlheinz Muenkel, Steffen Schuetz, Ulrich Dehnen
  • Patent number: 10843111
    Abstract: The invention relates to whole blood filter media and a process of filtering whole blood samples using a filter medium comprising particles, wherein the blood cells are retained inside the filter, and wherein the plasma or serum is separated from the blood cells.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: November 24, 2020
    Assignee: Mann+Hummel GmbH
    Inventors: Heike Rupp, Steffen Schuetz, Dagmar Winkler
  • Publication number: 20200359952
    Abstract: A whole blood filtration device is provided with a filter membrane separating a feeding volume and a clean side of the filter membrane from each other. The feeding volume communicates with a first feeding side opening and with a second feeding side opening. The filter membrane has pores with a pore size that ensures permeability of the filter membrane to blood plasma/serum and that retains blood cells. The first feeding side opening can be coupled to a first blood pump for feeding blood from the first feeding side opening into the feeding volume so that blood plasma/serum permeates the filter membrane and blood cells, retained by the filter membrane, exit from the feeding volume through the second feeding side opening.
    Type: Application
    Filed: June 3, 2020
    Publication date: November 19, 2020
    Inventors: Dagmar Winkler, Heike Rupp, Steffen Schuetz, Dietmar Talmon-Gros, Michael Fasold, Alfons-Alois Schwinghammer, Frank Bartel, Sascha Bauer, Patrick Nytz
  • Publication number: 20200289041
    Abstract: A whole blood filtration device is provided with a filter membrane separating a feeding volume and a clean side of the filter membrane from each other. The feeding volume communicates with a first feeding side opening and with a second feeding side opening. The filter membrane has pores with a pore size that ensures permeability of the filter membrane to blood plasma/serum and that retains blood cells. The first feeding side opening can be coupled to a first blood pump for feeding blood from the first feeding side opening into the feeding volume so that blood plasma/serum permeates the filter membrane and blood cells, retained by the filter membrane, exit from the feeding volume through the second feeding side opening.
    Type: Application
    Filed: June 3, 2020
    Publication date: September 17, 2020
    Inventors: Dagmar Winkler, Heike Rupp, Steffen Schuetz, Dietmar Talmon-Gros, Michael Fasold, Alfons-Alois Schwinghammer, Frank Bartel, Sascha Bauer, Patrick Nytz
  • Patent number: 10687750
    Abstract: A whole blood filtration device is provided with a filter membrane separating a feeding volume and a clean side of the filter membrane from each other. The feeding volume communicates with a first feeding side opening and with a second feeding side opening. The filter membrane has pores with a pore size that ensures permeability of the filter membrane to blood plasma/serum and that retains blood cells. The first feeding side opening can be coupled to a first blood pump for feeding blood from the first feeding side opening into the feeding volume so that blood plasma/serum permeates the filter membrane and blood cells, retained by the filter membrane, exit from the feeding volume through the second feeding side opening.
    Type: Grant
    Filed: December 29, 2015
    Date of Patent: June 23, 2020
    Assignee: MANN+ HUMMEL GmbH
    Inventors: Steffen Schuetz, Dagmar Winkler, Heike Rupp, Dietmar Talmon-Gros, Michael Fasold, Alfons-Alois Schwinghammer, Frank Bartel, Sascha Bauer, Patrick Nytz
  • Patent number: 10675399
    Abstract: A whole blood hollow fiber membrane filter medium is made of a polymeric material having pores of a pore size that ensures permeability to blood plasma or serum but retains blood cells. The whole blood hollow fiber membrane filter medium is used for filtering a whole blood sample so that blood plasma or serum passes through the whole blood hollow fiber membrane filter medium and blood cells are retained. The obtained blood plasma shows no hemolysis.
    Type: Grant
    Filed: November 11, 2015
    Date of Patent: June 9, 2020
    Assignee: MANN+HUMMEL GmbH
    Inventors: Steffen Schuetz, Heike Rupp, Dagmar Winkler, Frank Ehlen
  • Patent number: 10561781
    Abstract: A blood filtering device has a filtration section with filter medium separating raw side and clean side. A first communication path connects raw side and a first variable blood reservoir volume; a second communication path connects raw side and a second variable blood reservoir volume coupled to a receptacle. When varying the first variable blood reservoir volume, blood contained therein flows through first communication path to raw side, plasma/serum passes through the filter medium from raw side to clean side, and residual blood flows from raw side through second communication path into the second variable blood reservoir volume. When varying the second variable blood reservoir volume, blood contained therein flows through second communication path to raw side, plasma/serum passes through the filter medium from raw side to clean side, and residual blood flows from raw side through first communication path into first variable blood reservoir volume.
    Type: Grant
    Filed: December 12, 2015
    Date of Patent: February 18, 2020
    Assignee: MANN+HUMMEL GmbH
    Inventors: Dagmar Winkler, Heike Rupp, Claudio Weiss, Karlheinz Muenkel, Joachim Stinzendoerfer, Steffen Schuetz, Sascha Bauer, Frank Bartel, Alfons-Alois Schwinghammer, Michael Fasold, Dietmar Talmon-Gros, Norbert Strassenberger, Anton Rabanter
  • Publication number: 20200030747
    Abstract: A thermally sterilizable fluid filter (10) for concentrating substances contained in a fluid by way of micro-, nano- or ultrafiltration of the fluid, particularly for concentrating a pharmaceutical precursor and/or intermediate, in particular a vaccine, in a fluid. The fluid filter has a filter housing with a fluid inlet, a retentate outlet and a permeate outlet. A filter cartridge is arranged in the filter housing (12) and has a filter medium of a ceramic material and/or a ceramic composite material. The filter cartridge is arranged held with axial play on the filter housing.
    Type: Application
    Filed: October 7, 2019
    Publication date: January 30, 2020
    Inventors: Heike Rupp, Michael Fasold, Herbert Jainek, Sascha Bauer, Frank Ehlen, Stefan Kunze, Jasmin Sorg, Karlheinz Muenkel, Steffen Schuetz, Ulrich Dehnen
  • Patent number: 10500328
    Abstract: A whole blood hollow fiber membrane filter medium is provided with a ceramic material having pores of a pore size that ensures permeability to blood plasma or serum and its molecular components while blood cells are retained. The whole blood hollow fiber membrane filter medium is used for separating blood plasma from whole blood, wherein the blood plasma preferably shows no hemolysis.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: December 10, 2019
    Assignee: MANN+HUMMEL GmbH
    Inventors: Steffen Schuetz, Heike Rupp, Tobias Woerz, Dagmar Winkler, Kathrin Woerz, Frank Ehlen, Karlheinz Muenkel, Joachim Stinzendoerfer
  • Patent number: 10478780
    Abstract: A separating device for separating an undesired fluid from a multi-component liquid has a region flowed through by the multi-component liquid and at least one membrane disposed in the region to separate a first fluid region from a second fluid region. The membrane has a first permeability to the undesired fluid and a second permeability to the multi-component liquid. The first permeability is different from the second permeability. The membrane is equally permeable to all components of the multi-component liquid. The membrane is permeable to the multi-component liquid and impermeable to the undesired fluid, or the membrane is impermeable to the multi-component liquid and is permeable to the undesired fluid, wherein the multi-component liquid is a liquid multi-component operating medium. A filter with such a separating device and a filter element, in particular for diesel fuel, as well as a liquid system with such a separating device are described.
    Type: Grant
    Filed: August 24, 2017
    Date of Patent: November 19, 2019
    Assignee: MANN+HUMMEL GmbH
    Inventors: Heike Rupp, Steffen Schuetz, Dagmar Winkler
  • Patent number: 10350516
    Abstract: A blood filtering device has a tubular housing with a tubular section and tubular housing volume. A filtration section with a filter medium separating a raw side from a clean side is arranged in the tubular housing. The filtration section is movable along the tubular section and movably sealed relative to the tubular housing. The filtration section separates the tubular housing volume into variable first and second tubular housing volumes. A first communication path extends between raw side and first tubular housing volume. A second communication path exits between raw side and second tubular housing volume. When moving the filtration section, blood in the first tubular housing volume flows through the first communication path to the raw side; blood plasma passes through the filter medium to the clean side; residual blood flows through the second communication path into the variable second tubular housing volume.
    Type: Grant
    Filed: December 28, 2015
    Date of Patent: July 16, 2019
    Assignee: MANN+HUMMEL GmbH
    Inventors: Dagmar Winkler, Heike Rupp, Steffen Schuetz, Karlheinz Muenkel, Joachim Stinzendoerfer
  • Publication number: 20180078886
    Abstract: The invention relates to whole blood filter media and a process of filtering whole blood samples using a filter medium comprising particles, wherein the blood cells are retained inside the filter, and wherein the plasma or serum is separated from the blood cells.
    Type: Application
    Filed: November 30, 2017
    Publication date: March 22, 2018
    Inventors: Heike Rupp, Steffen Schuetz, Dagmar Winkler
  • Publication number: 20170354933
    Abstract: A separating device for separating an undesired fluid from a multi-component liquid has a region flowed through by the multi-component liquid and at least one membrane disposed in the region to separate a first fluid region from a second fluid region. The membrane has a first permeability to the undesired fluid and a second permeability to the multi-component liquid. The first permeability is different from the second permeability. The membrane is equally permeable to all components of the multi-component liquid. The membrane is permeable to the multi-component liquid and impermeable to the undesired fluid, or the membrane is impermeable to the multi-component liquid and is permeable to the undesired fluid, wherein the multi-component liquid is a liquid multi-component operating medium. A filter with such a separating device and a filter element, in particular for diesel fuel, as well as a liquid system with such a separating device are described.
    Type: Application
    Filed: August 24, 2017
    Publication date: December 14, 2017
    Inventors: Heike Rupp, Steffen Schuetz, Dagmar Winkler
  • Publication number: 20160129374
    Abstract: A blood filtering device has a tubular housing with a tubular section and tubular housing volume. A filtration section with a filter medium separating a raw side from a clean side is arranged in the tubular housing. The filtration section is movable along the tubular section and movably sealed relative to the tubular housing. The filtration section separates the tubular housing volume into variable first and second tubular housing volumes. A first communication path extends between raw side and first tubular housing volume. A second communication path exits between raw side and second tubular housing volume. When moving the filtration section, blood in the first tubular housing volume flows through the first communication path to the raw side; blood plasma passes through the filter medium to the clean side; residual blood flows through the second communication path into the variable second tubular housing volume.
    Type: Application
    Filed: December 28, 2015
    Publication date: May 12, 2016
    Inventors: Dagmar Winkler, Heike Rupp, Steffen Schuetz, Karlheinz Muenkel, Joachim Stinzendoerfer
  • Publication number: 20160106353
    Abstract: A whole blood filtration device is provided with a filter membrane separating a feeding volume and a clean side of the filter membrane from each other. The feeding volume communicates with a first feeding side opening and with a second feeding side opening. The filter membrane has pores with a pore size that ensures permeability of the filter membrane to blood plasma/serum and that retains blood cells. The first feeding side opening can be coupled to a first blood pump for feeding blood from the first feeding side opening into the feeding volume so that blood plasma/serum permeates the filter membrane and blood cells, retained by the filter membrane, exit from the feeding volume through the second feeding side opening.
    Type: Application
    Filed: December 29, 2015
    Publication date: April 21, 2016
    Inventors: Steffen Schuetz, Dagmar Winkler, Heike Rupp
  • Publication number: 20160106907
    Abstract: A blood filtering device has a filtration section with filter medium separating raw side and clean side. A first communication path connects raw side and a first variable blood reservoir volume; a second communication path connects raw side and a second variable blood reservoir volume coupled to a receptacle. When varying the first variable blood reservoir volume, blood contained therein flows through first communication path to raw side, plasma/serum passes through the filter medium from raw side to clean side, and residual blood flows from raw side through second communication path into the second variable blood reservoir volume. When varying the second variable blood reservoir volume, blood contained therein flows through second communication path to raw side, plasma/serum passes through the filter medium from raw side to clean side, and residual blood flows from raw side through first communication path into first variable blood reservoir volume.
    Type: Application
    Filed: December 12, 2015
    Publication date: April 21, 2016
    Inventors: Dagmar Winkler, Heike Rupp, Claudio Weiss, Karlheinz Muenkel, Joachim Stinzendoerfer, Steffen Schuetz, Sascha Bauer, Frank Bartel, Alfons-Alois Schwinghammer, Michael Fasold, Dietmar Talmon-Gros, Norbert Strassenberger, Anton Rabanter
  • Publication number: 20160096148
    Abstract: A whole blood hollow fiber membrane filter medium is provided with a ceramic material having pores of a pore size that ensures permeability to blood plasma or serum and its molecular components while blood cells are retained. The whole blood hollow fiber membrane filter medium is used for separating blood plasma from whole blood, wherein the blood plasma preferably shows no hemolysis.
    Type: Application
    Filed: December 14, 2015
    Publication date: April 7, 2016
    Inventors: Steffen Schuetz, Heike Rupp, Tobias Woerz, Dagmar Winkler, Kathrin Fischer, Frank Ehlen, Karlheinz Muenkel, Joachim Stinzendoerfer
  • Publication number: 20160074569
    Abstract: A whole blood hollow fiber membrane filter medium is made of a polymeric material having pores of a pore size that ensures permeability to blood plasma or serum but retains blood cells. The whole blood hollow fiber membrane filter medium is used for filtering a whole blood sample so that blood plasma or serum passes through the whole blood hollow fiber membrane filter medium and blood cells are retained. The obtained blood plasma shows no hemolysis.
    Type: Application
    Filed: November 11, 2015
    Publication date: March 17, 2016
    Inventors: Steffen Schuetz, Heike Rupp, Dagmar Winkler, Frank Ehlen