Patents by Inventor Heiko A. Haertel
Heiko A. Haertel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240041961Abstract: Assay method, comprising providing a plant capable of expressing a delta-12 desaturase, wherein said delta-12 desaturase has at least 50% total amino acid sequence identity to at least one of the sequences SEQ ID NO. 328 to 336, and/or at least 59% total amino acid sequence similarity to at least one of the sequences SEQ ID NO. 328 to 336, and wherein the plant is also capable of expressing at least one or more enzymes of unsaturated fatty acid metabolism, of which enzymes at least one is capable of using linoleic acid as a substrate, and of which enzymes at least one is supposedly connected to a plant metabolic property, growing the plant, and measuring said plant metabolic property for said plant.Type: ApplicationFiled: October 31, 2022Publication date: February 8, 2024Inventors: Toralf Senger, Heiko Haertel
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Publication number: 20230293615Abstract: T-DNA for expression of a target gene in a plant, wherein the T-DNA comprises a left and a right border element and at least one expression cassette comprising a promoter, operatively linked thereto a target gene, and downstream thereof a terminator, wherein the length of the T-DNA, measured from left to right border element and comprising the target gene, has a length of at least 30000 bp.Type: ApplicationFiled: January 31, 2023Publication date: September 21, 2023Inventors: Toralf Senger, Laurent Marty, Irene Kunze, Heiko Haertel, Steven Craig Bremmer, Steven D. Breazeale, Joerg Bauer, Patricia Vrinten, Sten Stymne, Jenny Lindberg Yilmaz, John A. McElver, Dietrich Rein, Carl Andre
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Patent number: 11613761Abstract: T-DNA for expression of a target gene in a plant, wherein the T-DNA comprises a left and a right border element and at least one expression cassette comprising a promoter, operatively linked thereto a target gene, and downstream thereof a terminator, wherein the length of the T-DNA, measured from left to right border element and comprising the target gene, has a length of at least 30000 bp.Type: GrantFiled: November 13, 2015Date of Patent: March 28, 2023Assignees: Bioriginal Food & Science Corporation, BASF Plant Science Company GmbHInventors: Toralf Senger, Laurent Marty, Irene Kunze, Heiko Haertel, Steven Craig Bremmer, Steven D. Breazeale, Joerg Bauer, Patricia Vrinten, Sten Stymne, Jenny Lindberg Yilmaz, John A. McElver, Dietrich Rein, Carl Andre
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Patent number: 11484560Abstract: Assay method, comprising providing a plant capable of expressing a delta-12 desaturase, wherein said delta-12 desaturase has at least 50% total amino acid sequence identity to at least one of the sequences SEQ ID NO. 328 to 336, and/or at least 59% total amino acid sequence similarity to at least one of the sequences SEQ ID NO. 328 to 336, and wherein the plant is also capable of expressing at least one or more enzymes of unsaturated fatty acid metabolism, of which enzymes at least one is capable of using linoleic acid as a substrate, and of which enzymes at least one is supposedly connected to a plant metabolic property, growing the plant, and measuring said plant metabolic property for said plant.Type: GrantFiled: November 13, 2015Date of Patent: November 1, 2022Assignee: BASF PLANT SCIENCE COMPANY GMBHInventors: Toralf Senger, Heiko A. Haertel
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Publication number: 20180291389Abstract: Assay method, comprising providing a plant capable of expressing a delta-12 desaturase, wherein said delta-12 desaturase has at least 50% total amino acid sequence identity to at least one of the sequences SEQ ID NO. 328 to 336, and/or at least 59% total amino acid sequence similarity to at least one of the sequences SEQ ID NO. 328 to 336, and wherein the plant is also capable of expressing at least one or more enzymes of unsaturated fatty acid metabolism, of which enzymes at least one is capable of using linoleic acid as a substrate, and of which enzymes at least one is supposedly connected to a plant metabolic property, growing the plant, and measuring said plant metabolic property for said plant.Type: ApplicationFiled: November 13, 2015Publication date: October 11, 2018Inventors: Toralf Senger, Heiko A. Haertel
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Publication number: 20150143584Abstract: This invention relates generally to nucleic acid sequences encoding proteins that are related to the presence of seed storage compounds in plants. More specifically, the present invention relates to Arabidopsis thaliana, Brassica napus, Glycine max and Oryza sativa nucleic acid sequences encoding sugar and lipid metabolism regulator proteins and the use of these sequences in transgenic plants. In particular, the invention is directed to methods fir manipulating sugar-related compounds and for increasing oil level and altering the fatty acid composition in plants and seeds. The invention further relates to methods of using these novel plant polypeptides to stimulate plant growth and/or to increase yield and/or composition of seed storage compounds.Type: ApplicationFiled: November 19, 2014Publication date: May 21, 2015Applicant: BASF PLANT SCIENCE GMBHInventors: Heiko A. Haertel, Garima Bhatt
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Patent number: 8916748Abstract: This invention relates generally to nucleic acid sequences encoding proteins that are related to the presence of seed storage compounds in plants. More specifically, the present invention relates to Arabidopsis thaliana, Brassica napus, Glycine max and Oryza sativa nucleic acid sequences encoding sugar and lipid metabolism regulator proteins and the use of these sequences in transgenic plants. In particular, the invention is directed to methods for manipulating sugar-related compounds and for increasing oil level and altering the fatty acid composition in plants and seeds. The invention further relates to methods of using these novel plant polypeptides to stimulate plant growth and/or to increase yield and/or composition of seed storage compounds.Type: GrantFiled: December 4, 2006Date of Patent: December 23, 2014Assignee: BASF Plant Science GmbHInventors: Heiko A. Haertel, Garima Bhatt
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Patent number: 8835714Abstract: Isolated nucleic acids and proteins associated with lipid and sugar metabolism regulation are provided. In particular, lipid metabolism proteins (LMP) and encoding nucleic acids originating from Arabidopsis thaliana are provided. The nucleic acids and proteins are used in methods of producing transgenic plants and modulating levels of seed storage compounds. Preferably, the seed storage compounds are lipids, fatty acids, starches or seed storage proteins.Type: GrantFiled: September 20, 2012Date of Patent: September 16, 2014Assignee: BASF Plant Science GmbHInventors: Volker Mittendorf, Heiko A. Haertel, Petra Cirpus
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Publication number: 20130283480Abstract: Isolated nucleic acids and proteins associated with lipid and sugar metabolism regulation are provided. In particular, lipid metabolism proteins (LMP) and encoding nucleic acids originating from Arabidopsis thaliana are provided. The nucleic acids and proteins are used in methods of producing transgenic plants and modulating levels of seed storage compounds. Preferably, the seed storage compounds are lipids, fatty acids, starches or seed storage proteins.Type: ApplicationFiled: June 27, 2013Publication date: October 24, 2013Inventors: VOLKER MITTENDORF, HEIKO A. HAERTEL, PETRA CIRPUS
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Patent number: 8513490Abstract: The present invention relates to Constitutive Triple Response-like (CTR1-like) nucleic acid sequences and the sugar and lipid metabolism regulator proteins encoded by the said nucleic acid sequences. Further, the present invention relates to the use of the aforementioned nucleic acid sequences and proteins in transgenic plants. In particular, the invention is directed to methods for manipulating sugar-related compounds and for increasing oil level and altering the fatty acid composition in plants and seeds. The invention further relates to methods of using these novel plant polypeptides to stimulate plant growth and/or to increase yield and/or composition of seed storage compounds.Type: GrantFiled: September 18, 2006Date of Patent: August 20, 2013Assignee: BASF Plant Science GmbHInventors: Heiko A. Härtel, Jermaine Gibson, Jeffrey A. Brown
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Patent number: 8492612Abstract: Isolated nucleic acids and proteins associated with lipid and sugar metabolism regulation are provided. In particular, lipid metabolism proteins (LMP) and encoding nucleic acids originating from Arabidopsis thaliana are provided. The nucleic acids and proteins are used in methods of producing transgenic plants and modulating levels of seed storage compounds. Preferably, the seed storage compounds are lipids, fatty acids, starches or seed storage proteins.Type: GrantFiled: June 13, 2012Date of Patent: July 23, 2013Assignee: BASF Plant Science GmbHInventors: Volker Mittendorf, Heiko A. Haertel, Petra Cirpus
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Patent number: 8426676Abstract: Described herein are inventions in the field of genetic engineering of plants, including combinations of nucleic acid molecules encoding pyruvate kinase subunits to improve agronomic, horticultural, and quality traits. This invention relates generally to the combination of nucleic acid sequences encoding pyruvate kinase proteins that are related to the presence of seed storage compounds in plants. More specifically, the present invention relates to the use of these combinations of these sequences, their order and direction in the combination, and the regulatory elements used to control expression and transcript termination in these combinations in transgenic plants. In particular, the invention is directed to methods for manipulating seed storage compounds in plants and seeds. The invention further relates to methods of using these novel combinations of polypeptides to stimulate plant growth and/or root growth and/or to increase yield and/or composition of seed storage compounds.Type: GrantFiled: April 29, 2008Date of Patent: April 23, 2013Assignee: BASF Plant Science GmbHInventors: Oliver Oswald, Heiko A. Härtel, Christoph Benning, Carl Andre
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Publication number: 20130045325Abstract: This invention relates generally to methods for preparing a plant, plant cell, or plant part with increased content in one or more of protein, oil, or one or more amino acids relative to a corresponding wild-type plant, plant cell, or plant part. Expression cassettes for achieving such gene expression manipulation, as well as recombinant constructs, vectors and plants, plant cells, or plant parts comprising the same, are also provided. Plants, plant cells, or plant parts with increased content in one or more of protein, oil, or one or more amino acids thus obtained may be useful in the preparation of foodstuffs and animal feeds. Plants, plant cells, or plant parts with increased content in one or more of protein, oil, or one or more amino acids thus obtained may also be useful in plant breeding programs for developing further hybrid or inbred lines.Type: ApplicationFiled: August 16, 2012Publication date: February 21, 2013Applicant: BASF Plant Science Company GmbHInventors: Heiko Härtel, Volker Haake, Alex Cernac, Jamie Härtel, Christopher Kafer
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Publication number: 20130045324Abstract: This invention relates generally to methods for preparing plants, plant cells, or plant parts with increased content in one or more of protein, oil, or one or more amino acids. The invention also relates to transgenic plants comprising multiple genes of interest including a nucleic acid molecule encoding a polypeptide having pyruvate kinase activity and a nucleic acid molecule encoding a trehalose-6-phosphate synthase (TPS) homolog. Expression cassettes for achieving such gene expression manipulation, as well as recombinant constructs, vectors and plants, plant cells, or plant parts comprising the same, are also provided. Plants, plant cells, or plant parts with increased content in one or more of protein, oil, or one or more amino acids thus obtained may be useful in preparing foodstuffs and animal feeds and in plant breeding programs for developing further hybrid or inbred lines.Type: ApplicationFiled: August 16, 2012Publication date: February 21, 2013Applicant: BASF Plant Science Company GmbHInventors: Hanping Guan, Heiko Härtel, Suzy M. Cocciolone
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Publication number: 20130045323Abstract: The present invention relates to methods for increasing the protein, oil, and/or amino acid content of a plant. The methods involve the manipulation of the expression level of trehalose-6-phosphate synthase (TPS) homologs. Expression cassettes for achieving such gene expression manipulation and transgenic plant cells and plants comprising the constructs and cassettes are also provided. Methods of plant breeding using these plants have also been developed.Type: ApplicationFiled: August 16, 2012Publication date: February 21, 2013Applicant: BASF PLANT SCIENCE COMPANY GMBHInventor: Heiko Härtel
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Patent number: 8362319Abstract: Isolated nucleic acids and polypeptides associated with lipid and sugar metabolism regulation are provided. In particular, lipid metabolism proteins (LMP) and encoding nucleic acids originating from Arabidopsis thaliana are provided. The nucleic acids and polypeptides are used in methods of producing transgenic plants and modulating levels of seed storage compounds in a plant. Preferably, the seed storage compounds are lipids, fatty acids, starches, or seed storage proteins.Type: GrantFiled: September 20, 2005Date of Patent: January 29, 2013Assignees: BASF Plant Science GmbH, Michigan State UniversityInventors: Carl Andre, Alex Cernac, Christoph Benning, Heiko A. Härtel, Volker Mittendorf
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Publication number: 20130025001Abstract: Isolated nucleic acids and proteins associated with lipid and sugar metabolism regulation are provided. In particular, lipid metabolism proteins (LMP) and encoding nucleic acids originating from Arabidopsis thaliana are provided. The nucleic acids and proteins are used in methods of producing transgenic plants and modulating levels of seed storage compounds. Preferably, the seed storage compounds are lipids, fatty acids, starches or seed storage proteins.Type: ApplicationFiled: September 20, 2012Publication date: January 24, 2013Applicant: BASF Plant Science GmbHInventors: Volker Mittendorf, Heiko A. Haertel, Petra Cirpus
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Publication number: 20120255067Abstract: Isolated nucleic acids and proteins associated with lipid and sugar metabolism regulation are provided. In particular, lipid metabolism proteins (LMP) and encoding nucleic acids originating from Arabidopsis thaliana are provided. The nucleic acids and proteins are used in methods of producing transgenic plants and modulating levels of seed storage compounds. Preferably, the seed storage compounds are lipids, fatty acids, starches or seed storage proteins.Type: ApplicationFiled: June 13, 2012Publication date: October 4, 2012Applicant: BASF Plant Science GmbHInventors: Volker Mittendorf, Heiko A. Haertel, Petra Cirpus
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Publication number: 20120255068Abstract: Isolated nucleic acids and proteins associated with lipid and sugar metabolism regulation are provided. In particular, lipid metabolism proteins (LMP) and encoding nucleic acids originating from Arabidopsis thaliana, Brassica napus, Glycine max, Oryza sativa, and Triticum aestivum are provided. The nucleic acids and proteins are used in methods of producing transgenic plants and modulating levels of seed storage compounds. Preferably, the seed storage compounds are lipids, fatty acids, starches, or seed storage proteins. The nucleic acids and proteins also are used in methods of modulating the seed size, seed number, seed weight, root length, and leaf size of plants.Type: ApplicationFiled: June 14, 2012Publication date: October 4, 2012Applicant: BASF Plant Science GmbHInventors: Garima Bhatt, Heiko A. Härtel, Volker Mittendorf, Karin J. Shank
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Patent number: 8278506Abstract: Isolated nucleic acids and proteins associated with lipid and sugar metabolism regulation are provided. In particular, lipid metabolism proteins (LMP) and encoding nucleic acids originating from Arabidopsis thaliana are provided. The nucleic acids and proteins are used in methods of producing transgenic plants and modulating levels of seed storage compounds. Preferably, the seed storage compounds are lipids, fatty acids, starches or seed storage proteins.Type: GrantFiled: May 9, 2011Date of Patent: October 2, 2012Assignee: BASF Plant Science GmbHInventors: Volker Mittendorf, Heiko A. Haertel, Petra Cirpus