Patents by Inventor Heinrich Gottlinger

Heinrich Gottlinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Infectious pseudotyped lentiviral vectors lacking matrix protein and uses thereof
    Patent number: 6479281
    Abstract: Vector systems that encode viral proteins that will assemble into an infectious lentivirus particle having a deletion of the lentiviral matrix are described. In one embodiment the vectors encode a lentiviral envelope protein that contains a deletion of the cytoplasmic tail. In a second embodiment a heterologous envelope as compared to the lentivirus is used such as an envelope protein that targets an endocytic compartment.
    Type: Grant
    Filed: September 26, 2000
    Date of Patent: November 12, 2002
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Heinrich Göttlinger, Heide Reil, Anatoly Bukovsky
  • Vectors containing HIV packaging sequences, packaging defective HIV vectors, and uses thereof
    Patent number: 5665577
    Abstract: Packaging defective and packaging proficient HIV vectors are disclosed. These vectors can be used to establish HIV packaging defective cell lines, and to package desired genes. These cell lines can be used in developing a vaccine, HIV antibodies and as part of a system for gene transfer. The packaging proficient vector can be used to target HIV target cells.
    Type: Grant
    Filed: November 15, 1993
    Date of Patent: September 9, 1997
    Assignee: Dana-Farber Cancer Institute
    Inventors: Joseph G. Sodroski, William A. Haseltine, Mark Poznansky, Andrew Lever, Heinrich Gottlinger