Abstract: The present invention relates to a method and a DNA nanostructure for detecting a target structure. In particular, the present invention relates to a DNA nanostructure, which ensures a preferably linear dependence on the number of marker molecules and the measurement signal regardless of the physical arrangement of a plurality of such DNA nanostructures by virtue of the skilled selection of the shape of the DNA nanostructure and the placement of the marker molecules attached to it. The invention additionally relates to the use of said DNA nanostructures and other nanoreporters, preferably in combination with adapters which bind specifically to target molecules, in a method for quantifying a plurality of target molecules, preferably in a simultaneous manner, using a multiplex method.

Abstract: The invention relates to a method and a DNA nanostructure for detecting a target structure. The invention relates in particular to a DNA nanostructure, which, by skillful selection of the shape of the DNA nanostructure and the placement of marker molecules fastened thereon, ensures a preferably linear dependence on the number of marker molecules and measurement signal, independent of the local arrangement of a plurality of such DNA nanostructures. The invention further relates to using said DNA nanostructures and other nano reporters, preferably in combination with adapters specifically binding to target molecules, in a method for the preferably simultaneous quantification of a plurality of target molecules, by means of a multiplex method. The method relates in particular to a single cell analysis.

Abstract: The present invention relates to a method and a DNA nanostructure for detecting a target structure. In particular, the present invention relates to a DNA nanostructure, which ensures a preferably linear dependence on the number of marker molecules and the measurement signal regardless of the physical arrangement of a plurality of such DNA nanostructures by virtue of the skilled selection of the shape of the DNA nanostructure and the placement of the marker molecules attached to it. The invention additionally relates to the use of said DNA nanostructures and other nanoreporters, preferably in combination with adapters which bind specifically to target molecules, in a method for quantifying a plurality of target molecules, preferably in a simultaneous manner, using a multiplex method.