Abstract: A method for producing a cationic liposomal preparation comprising a lipophilic active compound with physical and chemical stability during manufacturing, storing and reconstituting, and further a cationic liposomal preparation obtainable by this method as well as specific cationic liposomal preparations as well as pharmaceutical compositions are disclosed.

Abstract: A method for producing a cationic liposomal preparation comprising a lipophilic active compound with physical and chemical stability during manufacturing, storing and reconstituting, and further a cationic liposomal preparation obtainable by this method as well as specific cationic liposomal preparations as well as pharmaceutical compositions are disclosed.

Abstract: A method for producing a cationic liposomal preparation comprising a lipophilic active compound with physical and chemical stability during manufacturing, storing and reconstituting, and further a cationic liposomal preparation obtainable by this method as well as specific cationic liposomal preparations as well as pharmaceutical compositions are disclosed.

Abstract: The present invention relates to the use of cationic colloidal compositions for the targeted delivery of an active compound to an inflammatory site or an activated vascular site for the preparation of a medicament for the treatment of MS and in general for all CNS or PNS inflammatory neurodegenerative and demyelinating diseases and for diagnostic applications of such compositions.

Abstract: The present invention relates to a method of preparing liposomes in a single-pass mode. The method comprises the extusion of a solution or suspension through a porous device and subsequently passing said suspension or solution through a nozzle. Passing the suspension through said nozzle may result in an atomisation of the suspension or solution into droplets which might be employed in a subsequent spray-drying or spray-freezing process.

Abstract: The present invention relates to dry particles and methods of preparing the same, in particular to methods of producing dry particles comprising a thermally labile component such as a colloidal system or a thermally labile biopharmaceutical compound, to the use of such dry particles, and to pharmaceutical compositions comprising the same.

Abstract: A device and a method for data and/or energy transmission from a stationary part to a pane-shaped part which is movable relative to the stationary part, particularly a window pane of a motor vehicle, and/or vice versa. Data and/or energy is transmitted between an electrical unit in or on the stationary part and an electrical unit in or on a pane-shaped part which is movable relative to the stationary part, particularly an adjustable window pane, by electromagnetic interaction between at least one induction coil in the form of a conductor loop which is arranged in or on the pane-shaped movable part and at least one annular magnetic circuit which is arranged in or on the stationary part. Use of the device as an anti-trap protection for the pane-shaped movable part, particularly for the adjustable window pane of a vehicle, and/or as a theft protection for a vehicle is described.

Abstract: A method for producing a cationic liposomal preparation comprising a lipophilic active compound with physical and chemical stability during manufacturing, storing and reconstituting, and further a cationic liposomal preparation obtainable by this method as well as specific cationic liposomal preparations as well as pharmaceutical compositions are disclosed.

Abstract: The present invention relates to a method of stabilizing a low molecular weight compound in a cationic liposome, wherein said compound has a low solubility in a lipid membrane and/or a low permeability across a lipid membrane. Preferrably, the compound is modified in order to increase lipid membrane solubility and/or lipid membrane permeability. After delivery of the cationic liposome to a target site, particularly a target site in an organism, the modification is reversed and the low molecular weight compound may enact its desired activity.

Abstract: The invention relates to an improved method for producing homogenous colloidal nanoparticles, preferably liposomes, using a compounder.

Abstract: The present invention relates to an improved method of producing a colloidal nanoparticulate preparation comprising a camptothecin drug in its carboxylate form, a kit and a pharmaceutical composition.

Abstract: Disclosed are a transmitting device and a method for operating the transmitting device. The device includes long wave antennas, a multiplexer for activating an antenna, a power amplifier connected to a group of antennas and control unit for regulating the transmitter current.

Abstract: An improved method for producing a cationic liposomal preparation comprising a camptothecin drug with enhanced physical and chemical stability, a cationic liposomal preparation obtainable by this method and pharmaceutical compositions thereof are disclosed.

Abstract: The present invention relates to compositions, particularly colloidal nanoaggregates comprising the carboxylate form of a campothecin drug or a derivative thereof associated with at least one organic cationic molecule, which has a positive net charge. The composition or nanoaggregate may be present as an emulsion, droplet, mincelle, liposome, nanoparticle or nanocapsule.

Abstract: In a method for securing an object against unauthorized use, an interrogation unit (1) transmits an interrogation signal (s) and tests whether a response unit (2), which is to be carried by an authorized user, responds to the interrogation signal with a response signal (r) that contains as information a code authorized for desecuring a security device (3). If so, the security device is desecured. The securing method shall prevent unauthorized persons from establishing a radio link via relay stations between the interrogation unit (1) and the response unit (2) for providing the authorized code via this radio link without being noticed by the authorized user. The securing method prevents the desecuring of the security device (3) if the signal transit time of a signal transmitted as the interrogation signal (s) and received as the response signal (r) by the interrogation unit (1) during a monitoring time interval (t4–t5) is greater than a prescribed value.

Abstract: In automotive engineering transmitting and receiving stations are usually used in keyless locking systems as electronic key modules or evaluation units for identifying the key module. Deactivation of the locking system is prevented if the key module allocated by means of a clear identification number from the evaluation unit is not in the immediate vicinity of the evaluation unit. The novel method shall determine the distance between two transmitting and receiving stations with high resolution. According to the novel method, a transmission signal (S1, S2) respectively is generated in the transmitting and receiving stations (1, 2) and transmitted as a series of microwave pulses having a predefined pulse repetition frequency (fp1, fp2) to the other respective transmitting and receiving station (2, 1) and received thereby in the form of a received signal.

Abstract: The present invention relates to a non-vesicular preparation comprising at least one cationic amphiphile in an aqueous environment, its production and use and a cationic liposome suspension obtainable thereof with increase drug trap ratio and its areas of application such as pharmacology and medicine, particularly its use as carrier system for active substances.

Abstract: A method for producing a cationic liposomal preparation comprising a lipophilic active compound with physical and chemical stability during manufacturing, storing and reconstituting, and further a cationic liposomal preparation obtainable by this method as well as specific cationic liposomal preparations as well as pharmaceutical compositions are disclosed.

Abstract: The present invention relates to a method of stabilizing a low molecular weight compound in a cationic liposome, wherein said compound has a low solubility in a lipid membrane and/or a low permeability across a lipid membrane. Preferrably, the compound is modified in order to increase lipid membrane solubility and/or lipid membrane permeability. After delivery of the cationic liposome to a target site, particularly a target site in an organism, the modification is reversed and the low molecular weight compound may enact its desired activity.

Abstract: In a securing method for securing an object against unauthorized use, an interrogation unit (1) is used to transmit an interrogation signal (s) and to test whether a response unit (2), which is to be carried by and on an authorized user, responds to the interrogation signal with a response signal (s) that contains as information a code authorized for desecuring a security device (3). If that is the case, the security device is desecured. The securing method is, however, ineffective, if unauthorized persons establish a radio link via relay stations between the interrogation unit (1) and the response unit (2), and via this radio link provide the code authorized for the desecuring to the interrogation unit (1) without being noticed by the authorized user. The new securing method shall prevent such interventions by unauthorized persons.