Abstract: Transdermal therapeutic system comprising the active substance acetylsalicylic acid, having a layered structure consisting of a backing layer which is substantially impermeable to active substances and moisture and one or several active substance-containing matrix layers, which is characterized in that at least one of said matrix layers comprises acetylsalicylic acid in mainly crystalline form.

Abstract: The invention relates to a primary pack for surface-stabilized bandaging materials having a carrier layer and a skin-side contact surface having pressure sensitive adhesive areas and which prior to the use of the bandaging material is protected by a removable covering layer, and an at least one-layer supporting film detachably applied to the skin-remote surface of the carrier layer and which can be removed from the applied bandaging material, the supporting film forming part of the pack protecting the bandaging material.

Abstract: An application aid for one or several articles, such as therapeutic systems, plasters, labels, or the like, adhering to and positioned in a mechanically releasable manner on a carrier or covering layer, respectively, which extends in sheet-like form and particularly is flexible, in the form of cuts or predetermined breaking lines formed within the carrier or covering layer is characterized in that each article (2) is assigned a portion (4, 4a) of the carrier or cover layer (1), which portion laterally projects said article and is removable from the rest of the carrier or cover layer (1) by means of non-linear cuts or predetermined breaking lines, whereby the cuts or predetermined breaking lines connect two points at the edge of the carrier or cover layer and at least partially run below the contact surface of the articles, at least one of these points lies on that portion of the carrier or covering layer projecting the articles at the side, and the imaginary straight connecting line between these two points,

Abstract: The present invention relates to a therapeutic system for the retarded and controlled transdermal and transmucous administration of active substances via an impermeable backing layer, an active substance containing reservoir, a substantially drug-free but drug-permeable layer, and a removable protective layer, whereby the drug-free layer is brought into contact with the active substance reservoir only immediately prior or after application and then lies between reservoir and application surface, whereby at least a portion of the active substance diffusing from the reservoir is converted in the retardation layer into a non-bioavailable form. In this connection, the conversion into the non-bioavailable form may be carried out either by immobilization of the active substance, by chemical reactions, or by physical interactions.

Abstract: The present invention relates to a therapeutic system for the transdermal or transmucous administration of active substances via an impermeable backing layer, a reservoir which at least partially comprises active substance, is double-layered and consists of separate parts, and a protective layer, whereby the two reservoir members(a) are positioned substantially parallely on top of each other,(b) are separated from each other by a removable intermediate layer being impermeable to the active substances of said reservoir members,(c) either comprise active substance or auxiliary agents or both at concentrations not corresponding to the distribution equilibrium.

Abstract: The present invention relates to a superficial therapeutic system consisting of an impermeable backing layer, an active substance containing matrix, and a removable protective layer, in which the matrix comprises:a. antineoplastic active substanceb. a self-adhesive polyacrylatec. a water absorberand optionallyd. a non-adhesive hydrophilic polyacrylatee. a softener and/or penetration accelerator.