Patents by Inventor Heinz Dobeli

Heinz Dobeli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for producing hydrophobic polypeptides and proteins, and fusion proteins for use in producing same
    Patent number: 5750374
    Abstract: Methods are disclosed for the production and purification of hydrophobic fusion proteins production and purification of said hydrophobic polypeptides, proteins or peptides. Homogeneous monomeric .beta.-amyloid peptide and tests for screening amyloid toxicity-inhibiting drugs using this monomeric .beta.-amyloid peptide relate to these fusion proteins.
    Type: Grant
    Filed: June 29, 1994
    Date of Patent: May 12, 1998
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Heinz Dobeli, Nicholas Draeger, Gerda Huber Trottman, Peter Jakob, Dietrich Stuber
  • Affinity peptides
    Patent number: 5310663
    Abstract: Fusion proteins and a process for their purification by means of metal chelate affinity chromatography on NTA resins are provided by this invention.
    Type: Grant
    Filed: June 18, 1993
    Date of Patent: May 10, 1994
    Assignee: Hoffman-La Roche Inc.
    Inventors: Heinz Dobeli, Bernhard Eggimann, Reiner Gentz, Erich Hochuli, Dietrich Stuber
  • Affinity peptides
    Patent number: 5284933
    Abstract: Fusion proteins and a process for their purification by means of metal chelate affinity chromatography on NTA resins are provided by this invention.
    Type: Grant
    Filed: February 22, 1988
    Date of Patent: February 8, 1994
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Heinz Dobeli, Bernhard Eggimann, Reiner Gentz, Erich Hochuli, Dietrich Stuber
  • Metal chelate resins
    Patent number: 5047513
    Abstract: Metal chelate resins whose complexed nitrilotriacetic acid residues are bound to a carrier matrix via a spacer and which are suitable for metal chelate chromatography of proteins, especially those which contain neighboring histidines.
    Type: Grant
    Filed: October 15, 1990
    Date of Patent: September 10, 1991
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Heinz Dobeli, Frich Hochuli
  • Metal chelate resins
    Patent number: 4877830
    Abstract: Metal chelate resins whose complexed nitrilotriacetic acid residues are bound to a carrier matrix via a spacer and which are suitable for metal chelate chromatography of proteins, especially those which contain neighboring histidines.
    Type: Grant
    Filed: July 13, 1987
    Date of Patent: October 31, 1989
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Heinz Dobeli, Frich Hochuli