Patents by Inventor Heinz-Georg Jahnke

Heinz-Georg Jahnke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Device and method for measuring impedance in organotypic tissues
    Patent number: 10670576
    Abstract: The present invention refers to a device for measuring impedance in organotypic tissue comprising at least one recording chamber with a liquid permeable membrane supporting the organotypic tissue, at least one bottom electrode and at least one top electrode, wherein the liquid permeable membrane divides the recording chamber into a top chamber and a bottom chamber, wherein at least the bottom chamber contains culture medium for the organotypic tissue, and the bottom electrode(s) is/are located in the bottom chamber and the top electrode(s) is/are located in the top chamber, and wherein the organotypic tissue is located between the bottom electrode(s) and the top electrode(s). The present invention also refers to the use of the device according to the present invention for measuring impedance in organotypic tissue.
    Type: Grant
    Filed: January 18, 2017
    Date of Patent: June 2, 2020
    Assignee: Universität Leipzig
    Inventors: Andrea Robitzki, Andrée Rothermel, Heinz-Georg Jahnke, Ina Sternberger, Frank Striggow, Till Mack
  • DEVICE AND METHOD FOR MEASURING IMPEDANCE IN ORGANOTYPIC TISSUES
    Publication number: 20170191980
    Abstract: The present invention refers to a device for measuring impedance in organotypic tissue comprising at least one recording chamber with a liquid permeable membrane supporting the organotypic tissue, at least one bottom electrode and at least one top electrode, wherein the liquid permeable membrane divides the recording chamber into a top chamber and a bottom chamber, wherein at least the bottom chamber contains culture medium for the organotypic tissue, and the bottom electrode(s) is/are located in the bottom chamber and the top electrode(s) is/are located in the top chamber, and wherein the organotypic tissue is located between the bottom electrode(s) and the top electrode(s). The present invention also refers to the use of the device according to the present invention for measuring impedance in organotypic tissue.
    Type: Application
    Filed: January 18, 2017
    Publication date: July 6, 2017
    Applicant: Universität Leipzig
    Inventors: Andrea ROBITZKI, Andrée Rothermel, Heinz-Georg Jahnke, Ina Sternberger, Frank Striggow, Till Mack
  • Device and method for parallel recording of impedance spectra and field potential
    Patent number: 9551681
    Abstract: The present invention relates to a device and a method for parallel recording of impedance spectra and field potential of cells in vitro.
    Type: Grant
    Filed: August 13, 2012
    Date of Patent: January 24, 2017
    Assignee: Universitaet Leipzig
    Inventors: Andrea Robitzki, Heinz-Georg Jahnke, Ronny Azendorf
  • Polymutant tau protein variants and their use for recapitulating human tauopathies
    Patent number: 9527894
    Abstract: Disclosed herein are methods for identifying an agent for treating or preventing neurogenerative disease and to methods for recapitulating tauopathies using a tau protein that includes at least four different mutations that cause the condition frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17), and to nucleic acids encoding the tau protein.
    Type: Grant
    Filed: April 28, 2011
    Date of Patent: December 27, 2016
    Assignee: Universitaet Leipzig
    Inventors: Andrea Robitzki, Heinz-Georg Jahnke, Dana Krinke, Frank Striggow, Till Mack
  • DEVICE AND METHOD FOR PARALLEL RECORDING OF IMPEDANCE SPECTRA AND FIELD POTENTIAL
    Publication number: 20140346058
    Abstract: The present invention relates to a device and a method for parallel recording of impedance spectra and field potential of cells in vitro.
    Type: Application
    Filed: August 13, 2012
    Publication date: November 27, 2014
    Applicant: UNIVERSITAET LEIPZIG
    Inventors: Andrea Robitzki, Heinz-Georg Jahnke, Ronny Azendorf
  • POLYMUTANT TAU PROTEIN VARIANTS AND THEIR USE FOR RECAPITULATING HUMAN TAUOPATHIES
    Publication number: 20140162306
    Abstract: The present invention relates to a tau protein comprising at least four different mutations selected from group consisting of mutations which cause the condition frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17), and to nucleic acids encoding said tau protein. The invention further pertains to methods for identifying an agent for treating or preventing neurogenerative disease, and to methods for recapitulating tauopathies.
    Type: Application
    Filed: April 28, 2011
    Publication date: June 12, 2014
    Applicant: Universitaet Leipzig
    Inventors: Andrea Robitzki, Heinz-Georg Jahnke, Dana Krinke, Frank Striggow, Till Mack
  • DEVICE AND METHOD FOR MEASURING IMPEDANCE IN ORGANOTYPIC TISSUES
    Publication number: 20090247898
    Abstract: The present invention refers to a device for measuring impedance in organotypic tissue comprising at least one recording chamber with a liquid permeable membrane supporting the organotypic tissue, at least one bottom electrode and at least one top electrode, wherein the liquid permeable membrane divides the recording chamber into a top chamber and a bottom chamber, wherein at least the bottom chamber contains culture medium for the organotypic tissue, and the bottom electrode(s) is/are located in the bottom chamber and the top electrode(s) is/are located in the top chamber, and wherein the organotypic tissue is located between the bottom electrode(s) and the top electrode(s). The present invention also refers to the use of the device according to the present invention for measuring impedance in organotypic tissue.
    Type: Application
    Filed: February 24, 2009
    Publication date: October 1, 2009
    Applicant: KeyNeurotek Pharmaceuticals AG
    Inventors: Andrea ROBITZKI, Andree Rothermel, Heinz-Georg Jahnke, Ina Sternberger, Frank Striggow, Till Mack