Patents by Inventor Heinz-Georg Wetzstein

Heinz-Georg Wetzstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical compositions and treatment of mastitis
    Patent number: 10265330
    Abstract: The present invention relates to a pharmaceutical composition and methods of treating and/or preventing mastitis in non-human mammals. More particularly, the present invention relates to the treatment of mastitis in cows. The pharmaceutical composition comprises a mixture of a phosphonic acid and at least one antimicrobial.
    Type: Grant
    Filed: June 25, 2013
    Date of Patent: April 23, 2019
    Assignee: BAYER ANIMAL HEALTH GMBH
    Inventors: Robrecht Froyman, Heinz-Georg Wetzstein, Kristine Fraatz, Wolfgang Wiehl
  • PHARMACEUTICAL COMPOSITIONS AND TREATMENT OF MASTITIS
    Publication number: 20150164926
    Abstract: The present invention relates to a pharmaceutical composition and methods of treating and/or preventing mastitis in non-human mammals. More particularly, the present invention relates to the treatment of mastitis in cows. The pharmaceutical composition comprises a mixture of a phosphonic acid and at least one antimicrobial.
    Type: Application
    Filed: June 25, 2013
    Publication date: June 18, 2015
    Inventors: Robrecht Froyman, Heinz-Georg Wetzstein, Kristine Fraatz, Wolfgang Wiehl
  • Possibly substituted 8-cyano-1-cyclopropyl-7-(2,8-diazabicyclo-[4.3.0]-nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolin carboxylic acids and their derivatives
    Patent number: 6323213
    Abstract: The present invention relates to novel optionally substituted 8-cyano-1-cyclo-propyl-7-(2,8-diazabicyclo[4.3.
    Type: Grant
    Filed: August 13, 1998
    Date of Patent: November 27, 2001
    Assignee: Bayer Aktiengesellschaft
    Inventors: Stefan Bartel, Thomas Jaetsch, Thomas Himmler, Hans-Georg Rast, Werner Hallenbach, Ernst Heinen, Franz Pirro, Martin Scheer, Michael Stegemann, Hans-Peter Stupp, Heinz-Georg Wetzstein
  • Optionally substituted 8-cyano-1-cyclopropyl-7-(2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids and their derivatives
    Patent number: 6278013
    Abstract: Intermediates useful in the preparation of 8-cyano-1-cyclopropyl-7-(2,8-diazabicyclo[4.3.0]nonan-8-yl-6-fluorol,4-dihydro-4-oxo-3-quinolinecarboxylic acids of the following structures are claimed.
    Type: Grant
    Filed: November 21, 2000
    Date of Patent: August 21, 2001
    Assignee: Bayer Aktiengesellschaft
    Inventors: Stefan Bartel, Thomas Jaetsch, Thomas Himmler, Hans-Georg Rast, Werner Hallenbach, Ernst Heinen, Franz Pirro, Martin Scheer, Michael Stegemann, Hans-Peter Stupp, Heinz-Georg Wetzstein
  • Methods for decomposing quinolones and naphthyridones
    Patent number: 6046045
    Abstract: The present invention relates to two processes for the treatment of antimicrobially, in particular antibacterially, acting quinolone- and naphthyridonecarboxylic acids and derivatives thereof with wood rot fungi, if appropriate in the presence of water and/or inert solid or liquid substrates and further auxiliaries.
    Type: Grant
    Filed: April 17, 1998
    Date of Patent: April 4, 2000
    Assignee: Bayer Aktiengesellschaft
    Inventors: Heinz-Georg Wetzstein, Hans-Georg Rast, Wolfgang Karl, Rainer Martens, Frantisek Zadrazil
  • Pyrido?3,2,1-I,J!?3,1!benzoxazine derivatives
    Patent number: 5854241
    Abstract: Disclosed are pyrido?3,2,1-i,j!?3,1!benzoxazine compounds of the formula (I): ##STR1## wherein z represents a radical having the formula: ##STR2## wherein B represents --CH.sub.2 --, --O-- or a direct bond; and the other variables in formula (I) and Z are as described herein. The compounds have antibacterial properties and also disclosed are antibacterial compositions containing them and methods of using them to prevent or combat bacterial infections. Methods for preparing the compounds are also disclosed.
    Type: Grant
    Filed: January 3, 1997
    Date of Patent: December 29, 1998
    Assignee: Bayer Aktiengesellschaft
    Inventors: Werner Hallenbach, Thomas Himmler, Thomas Jaetsch, Burkhard Mielke, Klaus Dieter Bremm, Rainer Endermann, Franz Pirro, Michael Stegemann, Heinz-Georg Wetzstein
  • Thiazolo ?3,2-a! quinoline and thiazolo ?3,2-a! naphthyridine derivatives
    Patent number: 5744478
    Abstract: The present invention relates to new thiazolo?3,2-a!quinoline and thiazolo?3,2-a!naphthyridine derivatives of the general formula (I) ##STR1## in which R.sup.1, R.sup.2, Z and X have the meaning indicated in the description, processes for their preparation and their use in antibacterial compositions.
    Type: Grant
    Filed: February 21, 1997
    Date of Patent: April 28, 1998
    Assignee: Bayer Aktiengesellschaft
    Inventors: Thomas Jaetsch, Werner Hallenbach, Thomas Himmler, Klaus-Dieter Bremm, Rainer Endermann, Franz Pirro, Michael Stegemann, Heinz-Georg Wetzstein
  • 8-amino-10-(azabicycloalkyl)-pyrido?1,2,3-d,e!?1,3,4!benzoxadiazine derivatives
    Patent number: 5679675
    Abstract: The present invention relates to new 8-amino-10-(azabicycloalkyl)-pyrido?1,2,3-d,e!?1,3,4!benzoxadiazine derivatives of the general formula (I) ##STR1## in which the radicals R.sup.1 to R.sup.4, Z and X.sup.1 have the meaning given in the description, processes for their preparation and their use in antibacterial compositions.
    Type: Grant
    Filed: May 4, 1995
    Date of Patent: October 21, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Thomas Jaetsch, Burkhard Mielke, Uwe Petersen, Thomas Schenke, Klaus-Dieter Bremm, Rainer Endermann, Karl-Georg Metzger, Martin Scheer, Michael Stegemann, Heinz-Georg Wetzstein
  • 5-vinyl-and 5-ethinyl-quinolone- and -naphthyridone-carboxylic acids
    Patent number: 5659038
    Abstract: The invention relates to new 5-vinyl- and 5-ethinylquinolone- and -naphthyridonecarboxylic acids, to processes for their preparation, and to antibacterial compositions and feed additives containing them.
    Type: Grant
    Filed: May 3, 1996
    Date of Patent: August 19, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Thomas Himmler, Uwe Petersen, Klaus-Dieter Bremm, Rainer Endermann, Michael Stegemann, Heinz-Georg Wetzstein
  • 1,9-bridged thiazolo[3,2-a]quinoline derivatives
    Patent number: 5618815
    Abstract: The present invention relates to 1,9-bridged thiazolo[3,2-a]quinoline derivatives of the general formula (I) ##STR1## in which the substituents Z, X, R.sup.1 have the meaning given in the description, to processes for their preparation and to their use in antibacterial compositions.
    Type: Grant
    Filed: May 19, 1995
    Date of Patent: April 8, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Thomas Jaetsch, Werner Hallenbach, Thomas Himmler, Burkhard Mielke, Klaus D. Bremm, Rainer Endermann, Franz Pirro, Michael Stegemann, Heinz-Georg Wetzstein
  • 5-vinyl- and 5-ethinyl-quinolone- carboxylic acids
    Patent number: 5578604
    Abstract: The invention relates to new 5-vinyl- and 5-ethinyl-quinolone- and -naphthyridonecarboxylic acids, to processes for their preparation, and to antibacterial compositions and feed additives containing them.
    Type: Grant
    Filed: March 3, 1995
    Date of Patent: November 26, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Thomas Himmler, Uwe Petersen, Klaus-Dieter Bremm, Rainer Endermann, Michael Stegemann, Heinz-Georg Wetzstein
  • Pyrido[1,2,3-D,E] [1,3,4]benzoxadiazine derivatives
    Patent number: 5508278
    Abstract: Novel bactericidal pyrido[1,2,3-d,e,][1,3,4]benzoxadiazine derivatives of the formula (I) ##STR1## in which R.sup.1 is hydrogen or C.sub.1 -C.sub.4 -alkyl optionally substituted by hydroxyl or halogen,R.sup.2 independently of R.sup.1 is hydrogen or methyl,R.sup.3 is hydrogen or C.sub.1 -C.sub.4 -alkyl,R.sup.4 is hydrogen, C.sub.1 -C.sub.4 -alkyl optionally substituted by hydroxyl, methoxy, amino, methylamino or dimethylamino, or (5-methyl-2-oxo-1,3-dioxol-4-yl)-methyl,X.sup.
    Type: Grant
    Filed: August 26, 1994
    Date of Patent: April 16, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Thomas Jaetsch, Burkhard Mielke, Uwe Petersen, Thomas Philipps, Thomas Schenke, Klaus D. Bremm, Rainer Endermann, Karl G. Metzger, Martin Scheer, Michael Stegemann, Heinz-Georg Wetzstein