Patents by Inventor Heinz-Gerhard Kohn

Heinz-Gerhard Kohn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11247215
    Abstract: A centrifuge includes a swing rotor. Rotor arms of the swing rotor have recesses into which hangers of the swing rotor at least partially swing in a swung-out state. As a result, the centrifuge container and thus also the centrifuges are more compact, because the swinging-out requires less space. An inertial mass of the swing rotor is reduced due to the recesses provided therein, whereby energy consumption, primarily when starting the centrifuge, is significantly reduced.
    Type: Grant
    Filed: November 15, 2018
    Date of Patent: February 15, 2022
    Assignee: Eppendorf AG
    Inventors: Steffen Kühnert, Heinz Gerhard Köhn
  • Patent number: 10717960
    Abstract: This patent document relates to the field of biotechnological apparatuses. It relates particularly to a biotechnological apparatus comprising a bioreactor, an exhaust gas temperature control device and a method for treating an exhaust gas stream. This patent document further relates to a connection device for a sterile single-use fluid conduit of a single-use bioreactor and to a method for treating a fluid stream. The reusable connection device comprises a receptacle in which a portion of the fluid conduit can be detachably arranged, and a coupling member connecting the connection device to a temperature control device, the receptacle having a contact surface which is arranged such that the contact surface abuts a fluid conduit arranged in the receptacle, and wherein a portion of a fluid conduit can be introduced into the receptacle in a direction running substantially orthogonally to a longitudinal axis of the connection device.
    Type: Grant
    Filed: October 10, 2012
    Date of Patent: July 21, 2020
    Assignee: DASGIP INFORMATION AND TECHNOLOGY GMBH
    Inventors: Matthias Arnold, Heinz Gerhard Köhn, Nico Gülzow, Sven Eikelmann, Guido Ertel, Sebastian Selzer
  • Publication number: 20190143341
    Abstract: A centrifuge includes a swing rotor. Rotor arms of the swing rotor have recesses into which hangers of the swing rotor at least partially swing in a swung-out state. As a result, the centrifuge container and thus also the centrifuges are more compact, because the swinging-out requires less space. An inertial mass of the swing rotor is reduced due to the recesses provided therein, whereby energy consumption, primarily when starting the centrifuge, is significantly reduced.
    Type: Application
    Filed: November 15, 2018
    Publication date: May 16, 2019
    Inventors: Steffen Kühnert, Heinz Gerhard Köhn
  • Patent number: 10030220
    Abstract: A single-use bioreactor, suitable in particular for use in a parallel bioreactor system for applications in cell culture and/or microbiology, a head plate for such a single-use bioreactor and a process for manufacturing the single-use bioreactor and the head plate. The single-use bioreactor comprises a head plate, a dimensionally stable container and a mixer, the head plate and the container enclosing a reaction chamber, and the mixer having a mixer shaft and a stirring member, said mixer shaft being mounted rotatably about a rotational axis in a bearing and the stirring member being fastened torsionally rigidly to the mixer shaft. The mixer and the bearing are arranged entirely within the reaction chamber and the mixer shaft has a magnetic portion which is arranged and adapted in such a way that it can be coupled magnetically in an axial direction to a rotary drive.
    Type: Grant
    Filed: June 13, 2013
    Date of Patent: July 24, 2018
    Assignee: EPPENDORF AG
    Inventors: Matthias Arnold, Heinz Gerhard Kohn, Nico Gulzow, Sven Eikelmann, Sebastian Selzer, Jochen Beese, Christopher Gunther, Eckart Kopowski
  • Patent number: 9835600
    Abstract: A system for titrating liquids, with a syringe or tip, comprising a holding device and at least one tag and a metering equipment, comprising an additional holding device for holding the syringe or tip on the holding device, a reading device for reading the tag of the syringe or tip held by the additional holding device, a driving device having a motor, which is detachably coupled with a plunger of the syringe when the same is held by the additional holding device, or which is coupled with a plunger which is arranged in a cylinder which is coupled with the tip via a fluid conduit, when the same is held by the additional holding device, an operating device for operating the metering equipment and a control device, connected with the operating device, the reading device and the driving device, which controls the movement of the plunger depending of the tag of the inserted syringe or tip.
    Type: Grant
    Filed: January 21, 2014
    Date of Patent: December 5, 2017
    Assignee: EPPENDORF AG
    Inventors: Heinz-Gerhard Köhn, Karl-Friedrich Andres
  • Patent number: 9149815
    Abstract: The present invention relates to a lid for closing a centrifuge rotor, characterized by a form-fitting, rotation-actuated closure mechanism which, pre-positioned on the centrifuge rotor, moves automatically into a closed position by virtue of the intrinsic weight of the lid.
    Type: Grant
    Filed: May 23, 2006
    Date of Patent: October 6, 2015
    Assignee: Eppendorf AG
    Inventors: Heinz Gerhard Köhn, Eckhard Kopowski, Andreas Heilmann
  • Publication number: 20150132840
    Abstract: A single-use bioreactor, suitable in particular for use in a parallel bioreactor system for applications in cell culture and/or microbiology, a head plate for such a single-use bioreactor and a process for manufacturing the single-use bioreactor and the head plate. The single-use bioreactor comprises a head plate, a dimensionally stable container and a mixer, the head plate and the container enclosing a reaction chamber, and the mixer having a mixer shaft and a stirring member, said mixer shaft being mounted rotatably about a rotational axis in a bearing and the stirring member being fastened torsionally rigidly to the mixer shaft. The mixer and the bearing are arranged entirely within the reaction chamber and the mixer shaft has a magnetic portion which is arranged and adapted in such a way that it can be coupled magnetically in an axial direction to a rotary drive.
    Type: Application
    Filed: June 13, 2013
    Publication date: May 14, 2015
    Inventors: Matthias Arnold, Heinz-Gerhard Kohn, Nico Gulzow, Eikelmann Sven, Sebastian Selzer, Jochen Beese, Christoph Gunther, Eckhart Kopowski
  • Publication number: 20140329224
    Abstract: This patent document relates to the field of biotechnological apparatuses. It relates particularly to a biotechnological apparatus comprising a bioreactor, an exhaust gas temperature control device and a method for treating an exhaust gas stream. This patent document further relates to a connection device for a sterile single-use fluid conduit of a single-use bioreactor and to a method for treating a fluid stream. The reusable connection device comprises a receptacle in which a portion of the fluid conduit can be detachably arranged, and a coupling member connecting the connection device to a temperature control device, the receptacle having a contact surface which is arranged such that the contact surface abuts a fluid conduit arranged in the receptacle, and wherein a portion of a fluid conduit can be introduced into the receptacle in a direction running substantially orthogonally to a longitudinal axis of the connection device.
    Type: Application
    Filed: October 10, 2012
    Publication date: November 6, 2014
    Inventors: Matthias Arnold, Heinz-Gerhard Köhn, Nico Gülzow, Sven Eickelmann, Guido Ertel, Sebastian Selzer
  • Publication number: 20140134076
    Abstract: A system for titrating liquids, with a syringe or tip, comprising a holding device and at least one tag and a metering equipment, comprising an additional holding device for holding the syringe or tip on the holding device, a reading device for reading the tag of the syringe or tip held by the additional holding device, a driving device having a motor, which is detachably coupled with a plunger of the syringe when the same is held by the additional holding device, or which is coupled with a plunger which is arranged in a cylinder which is coupled with the tip via a fluid conduit, when the same is held by the additional holding device, an operating device for operating the metering equipment and a control device, connected with the operating device, the reading device and the driving device, which controls the movement of the plunger depending of the tag of the inserted syringe or tip.
    Type: Application
    Filed: January 21, 2014
    Publication date: May 15, 2014
    Applicant: EPPENDORF AG
    Inventors: Heinz-Gerhard Köhn, Karl-Friedrich Andres
  • Patent number: 8661920
    Abstract: A handheld pipetting apparatus for metering liquids, with a handleable pipette housing, at least one accommodation for a fastening portion of a syringe cylinder of a syringe, at least one plunger accommodation in an accommodation body for a plunger fastening portion of a syringe plunger of the syringe, syringe and plunger gripping levers for detachably holding the fastening portion in the accommodation and the plunger fastening portion in the plunger accommodation, at least one displacement device with a displacement chamber and a shiftable chamber wall limiting the same, for displacing a fluid; at least one seat for detachably holding a pipette point, a channel, connecting a hole in the seat with a displacement chamber, and at least one drive device, which is connected to couplable with the accommodation body the and/or the chamber wall, for shifting the accommodation body with respect to the accommodation, the and/or the chamber wall with respect to the displacement chamber.
    Type: Grant
    Filed: September 22, 2010
    Date of Patent: March 4, 2014
    Assignee: Eppendorf AG
    Inventors: Peter Molitor, Karl-Friedrich Andres, Steffen Hofmann, Heinz-Gerhard Köhn
  • Patent number: 8632735
    Abstract: A system for titrating liquids, with a syringe or tip, comprising a holding device and at least one tag and a metering equipment, comprising an additional holding device for holding the syringe or tip on the holding device, a reading device for reading the tag of the syringe or tip held by the additional holding device, a driving device having a motor, which is detachably coupled with a plunger of the syringe when the same is held by the additional holding device, or which is coupled with a plunger which is arranged in a cylinder which is coupled with the tip via a fluid conduit, when the same is held by the additional holding device, an operating device for operating the metering equipment and a control device, connected with the operating device, the reading device and the driving device, which controls the movement of the plunger depending of the tag of the inserted syringe or tip.
    Type: Grant
    Filed: January 18, 2007
    Date of Patent: January 21, 2014
    Assignee: Eppendorf AG
    Inventors: Heinz-Gerhard Kohn, Karl-Friedrich Andres
  • Publication number: 20110212819
    Abstract: The present invention relates to a lid for closing a centrifuge rotor, characterized by a form-fitting, rotation-actuated closure mechanism which, pre-positioned on the centrifuge rotor, moves automatically into a closed position by virtue of the intrinsic weight of the lid.
    Type: Application
    Filed: May 23, 2006
    Publication date: September 1, 2011
    Inventors: Heinz Gerhard Köhn, Eckhard Kopowski, Andreas Heilmann
  • Publication number: 20110072915
    Abstract: A handheld pipetting apparatus for metering liquids, with a handleable pipette housing, at least one accommodation for a fastening portion of a syringe cylinder of a syringe, at least one plunger accommodation in an accommodation body for a plunger fastening portion of a syringe plunger of the syringe, fastening means for detachably holding the fastening portion in the accommodation and the plunger fastening portion in the plunger accommodation, at least one displacement device with a displacement chamber and a shiftable chamber wall limiting the same, for displacing a fluid; at least one seat for detachably holding a pipette point, a channel, connecting a hole in the seat with a displacement chamber, and at least one drive device, which is connected to and/or couplable with the accommodation body and/or the chamber wall, for shifting the accommodation body with respect to the accommodation, and/or the chamber wall with respect to the displacement chamber.
    Type: Application
    Filed: September 22, 2010
    Publication date: March 31, 2011
    Applicant: EPPENDORF AG
    Inventors: Peter Molitor, Karl Friedrich Andres, Steffen Hofmann, Heinz-Gerhard Kohn
  • Publication number: 20090197775
    Abstract: The present invention pertains to a method for determining point mutations on micro-arrays/biochips using a nuclease capable to selectively digest hybridized DNA strands into two DNA fragments, said hybridized DNA strands containing a nucleotide mismatch or nucleotide deletion. The occurrence and/or location of such DNA fragments are indicative for a point mutation.
    Type: Application
    Filed: October 8, 2008
    Publication date: August 6, 2009
    Applicant: Eppendorf AG
    Inventors: Till Bachmann, Timo Barl, Heinz Gerhard Kohn
  • Publication number: 20080227658
    Abstract: The present invention discloses an improved cDNA microarray, which employs spacers of random sequence and a length of the spacers of at least 50 to 80 nucleotides. The inventive cDNA microarray may be employed for example in fields like the determination of gene expression, DNA sequencing, fingerprinting or mapping. In addition, a method for the preparation of the cDNA microarray, the use of spacer molecules with random sequence and a kit are specified.
    Type: Application
    Filed: March 8, 2006
    Publication date: September 18, 2008
    Applicant: EPPENDORF AG
    Inventors: Sven Bulow, Heinz-Gerhard Kohn, Jose Remacle
  • Publication number: 20070203457
    Abstract: A system for titrating liquids, with a syringe or tip, comprising a holding device and at least one tag and a metering equipment, comprising an additional holding device for holding the syringe or tip on the holding device, a reading device for reading the tag of the syringe or tip held by the additional holding device, a driving device having a motor, which is detachably coupled with a plunger of the syringe when the same is held by the additional holding device, or which is coupled with a plunger which is arranged in a cylinder which is coupled with the tip via a fluid conduit, when the same is held by the additional holding device, an operating device for operating the metering equipment and a control device, connected with the operating device, the reading device and the driving device, which controls the movement of the plunger depending of the tag of the inserted syringe or tip.
    Type: Application
    Filed: January 18, 2007
    Publication date: August 30, 2007
    Applicant: Eppendorf AG
    Inventors: Heinz-Gerhard Kohn, Karl-Friedrich Andres
  • Patent number: 7153433
    Abstract: Application of a functionalized porous membrane to purify nucleic acids, the binding properties of the membrane with respect to nucleic acids being adjustable by controlling the conditions of an ambient medium. The membrane is functionalized by deprotonated groups.
    Type: Grant
    Filed: February 2, 2001
    Date of Patent: December 26, 2006
    Assignee: Eppendorf AG
    Inventors: Thomas Kolzau, Heinz Gerhard Köhn, Wilhelm Plüster, Mathias Ulbricht
  • Patent number: 6872570
    Abstract: A laboratory device for jointly tempering reaction samples in at least two steps in respectively assigned, specified temperature ranges, which are carried out repeatedly and consecutively as sequences of steps, the laboratory tempering device, in one step of the sequences of steps, bringing several groups of samples, in each case containing at least one sample, to temperatures within the temperature range, which are constant within the groups and different between the groups, wherein the laboratory tempering device, in each step of the sequence, brings a different partial amount of the samples in groups to temperatures, which are the same within the groups and different between the groups, and brings the samples of the other partial amounts to a same temperature within the assigned temperature range.
    Type: Grant
    Filed: December 11, 2001
    Date of Patent: March 29, 2005
    Assignee: Eppendorf AG
    Inventor: Heinz Gerhard Köhn
  • Publication number: 20030096396
    Abstract: A laboratory device for jointly tempering reaction samples in at least two steps in respectively assigned, specified temperature ranges, which are carried out repeatedly and consecutively as sequences of steps, the laboratory tempering device, in one step of the sequences of steps, bringing several groups of samples, in each case containing at least one sample, to temperatures within the temperature range, which are constant within the groups and different between the groups, wherein the laboratory tempering device, in each step of the sequence, brings a different partial amount of the samples in groups to temperatures, which are the same within the groups and different between the groups, and brings the samples of the other partial amounts to a same temperature within the assigned temperature range.
    Type: Application
    Filed: December 11, 2001
    Publication date: May 22, 2003
    Inventor: Heinz Gerhard Kohn
  • Publication number: 20020187249
    Abstract: A process for the production of surface-functionalized supports that serve as starting products for the production of microarrays for immobilizing biomolecules, in which process the surface of a support is coated with an initiator and the coated surface is then put in contact with a solution containing at least one first group of polymerizable monomers, whereby the monomers contain binding sites onto which the biomolecules (probe molecules) can bond, and whereby the conditions under which the monomers are put in contact with the activated support are selected in such a way that the monomers, mediated by the initiator, bind to the support and, on that basis, polymerize to form functional polymer chains in such a manner that a fixed structure consisting of adjacent functional polymer chains is formed on the surface of the support.
    Type: Application
    Filed: February 1, 2002
    Publication date: December 12, 2002
    Inventors: Wilhelm Pluster, Mathias Ulbricht, Heinz Gerhard Kohn