Patents by Inventor Heinz Hartmut Seliger

Heinz Hartmut Seliger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oligoribonucleotide and ribozyme analogs with terminal 3?—3? and/or 5?—5? linkages
    Patent number: 6420546
    Abstract: The invention relates to oligoribonucleotide analogs with terminal 3′—3′ and/or 5′—5′ internucleotide linkages. This modification stabilizes the molecules altered in this way, including ribozymes, without adversely altering their properties, including, where appropriate, catalytic activities.
    Type: Grant
    Filed: April 14, 1998
    Date of Patent: July 16, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Heinz Hartmut Seliger, Flavio Ramalho Ortigao, Hannelore Rösch, Rudi Rösch, Bernd Krist
  • Modified phosphoramidite process for the production of modified nucleic acids
    Patent number: 5902878
    Abstract: The subject matter of the invention is a modified phosphoramidite process for the synthesis of nucleotide sequences. By use of a modified nucleoside phosphoramidite it is possible to produce nucleotide sequences which have a modified phosphate residue.
    Type: Grant
    Filed: September 19, 1997
    Date of Patent: May 11, 1999
    Assignee: Boehringer Mannheim GmbH
    Inventors: Heinz-Hartmut Seliger, Sibylle Berner, Klaus Muhlegger, Herbert Von Der Eltz, Hans-Georg Batz
  • Modified phosphoramidite process for the production of modified nucleic acids
    Patent number: 5700919
    Abstract: The subject matter of the invention is a modified phosphoramidite process for the synthesis of nucleotide sequences. By use of a modified nucleoside phosphoramidite it is possible to produce nucleotide sequences which have a modified phosphate residue.
    Type: Grant
    Filed: January 10, 1995
    Date of Patent: December 23, 1997
    Assignee: Boehringer Mannhiem GmbH
    Inventors: Heinz-Hartmut Seliger, Sibylle Berner, Klaus Muhlegger, Herbert Von der Eltz, Hans-Georg Batz