Patents by Inventor Heinz-Jurgen Friesen

Heinz-Jurgen Friesen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds from biopolymers and effector substances which are linked via optically active amino acid derivatives, processes for the preparation thereof and the use thereof
    Patent number: 5773271
    Abstract: Compounds from biopolymers and effector substances which are linked via optically active amino acid derivatives, processes for the preparation thereof and the use thereof.The invention relates to compounds from biopolymers and effector substances which are linked with the aid of derivatives of optically active amino acids in which the amino group has been converted into a maleimido group and the carboxyl group into an active easter group.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: June 30, 1998
    Assignee: Behring Diagnostics GmbH
    Inventors: Heinz-Jurgen Friesen, Peter Hermentin
  • Compounds from biopolymers and effector substances which are linked via optically active amino acid derivatives, processes for the preparation thereof and the use thereof
    Patent number: 5744315
    Abstract: Compounds from biopolymers and effector substances which are linked via optically active amino acid derivatives, processes for the preparation thereof and the use thereof. The invention relates to compounds from biopolymers and effector substances which are linked with the aid of derivatives of optically active amino acids in which the amino group has been converted into a maleimido group and the carboxyl group into an active ester group.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: April 28, 1998
    Assignee: Behring Diagnostics GmbH
    Inventors: Heinz-Jurgen Friesen, Peter Hermentin
  • Biopolymer and effector substance conjugates, process for the preparation thereof and their use
    Patent number: 5484722
    Abstract: The invention relates to compounds from biopolymers and effector substances which are linked with the aid of derivatives of optically active amino acids in which the amino group has been converted into a maleimido group and the carboxyl group into an active ester group, processes for the preparation thereof and the use thereof.
    Type: Grant
    Filed: February 24, 1994
    Date of Patent: January 16, 1996
    Assignee: Behringwerke Aktiengesellschaft
    Inventors: Heinz-Jurgen Friesen, Peter Hermentin
  • Compounds from biopolymers and effector substances which are linked via optically active amino acid derivatives, processes for the preparation thereof and the use thereof
    Patent number: 5321142
    Abstract: The invention relates to compounds from biopolymers and effector substances which are linked with the aid of derivatives of optically active amino acids in which the amino group has been converted into a maleimido group and the carboxyl group into an active ester group.
    Type: Grant
    Filed: July 6, 1990
    Date of Patent: June 14, 1994
    Assignee: Behringwerke Aktiengesellschaft
    Inventors: Heinz-Jurgen Friesen, Peter Hermentin
  • Magnetic protein conjugates, a process for the preparation thereof and the use thereof
    Patent number: 5095097
    Abstract: The invention relates to magnetic protein conjugates of the formula IM--NH--CO--(CH.sub.2).sub.n --S--P' Iwith n=1-6, preferably with a n=1 or 2 and particularly preferably with n=1, in which M is a dispersible, magnetically reacting material or particle which carries amino groups, and P' is a protein, to a process for the preparation thereof and to the use thereof for the specific removal of cells or soluble antigens, receptors, substrates, cofactors or carbohydrate determinants from aqueous salt solutions or body fluids or as part of a diagnostic method or as a diagnostic aid, preferably for the removal of cells, preferably for bone marrow depletion or for HLA typing.
    Type: Grant
    Filed: June 15, 1990
    Date of Patent: March 10, 1992
    Assignee: Behringwerke Aktiengesellschaft
    Inventors: Peter Hermentin, Reiner Donges, Udo Franssen, Karlheinz Enssle, Heinz-Jurgen Friesen
  • Preparation of homogeneous human fibroblast interferon
    Patent number: 5015730
    Abstract: Human fibroblast interferon has been purified to homogeneity by use of a novel procedure combining affinity chromatography and high pressure liquid chromatography (HPLC).
    Type: Grant
    Filed: July 14, 1989
    Date of Patent: May 14, 1991
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Heinz-Jurgen Friesen, Sidney Pestka
  • Sheet-like diagnostic device
    Patent number: 4861711
    Abstract: A solid diagnostic device for the quantitative determination of substances of biological affinity in biological fluids is described. A process is also described in which the biological fluid is brought into contact with a specific functional sector of the device, the fluid migrates through several functional sectors situated beside one another and containing suitable reagent components, and one or more substances of biological affinity are detected in such functional sectors which contain, for each substance to be detected, at least one combination partner of biological affinity, attached to a solid phase.
    Type: Grant
    Filed: December 13, 1985
    Date of Patent: August 29, 1989
    Assignee: Behringwerke Aktiengesellschaft
    Inventors: Heinz-Jurgen Friesen, Gerd Grenner, Hans-Erwin Pauly, Helmut Kohl, Klaus Habenstein, Joseph Stark
  • Preparation of homogeneous human fibroblast interferon
    Patent number: 4289689
    Abstract: Human fibroblast interferon has been purified to homogeneity by use of a novel procedure combining affinity chromatography and high pressure liquid chromatography (HPLC).
    Type: Grant
    Filed: June 19, 1980
    Date of Patent: September 15, 1981
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Heinz-Jurgen Friesen, Sidney Pestka
  • Sheet-like diagnostic device
    Patent number: RE38688
    Abstract: A solid diagnostic device for the quantitative determination of substances of biological affinity in biological fluids is described. A process is also described in which the biological fluid is brought into contact with a specific functional sector of the device, the fluid migrates through several functional sectors situated beside one another and containing suitable reagent components, and one or more substances of biological affinity are detected in such functional sectors which contain, for each substance to be detected, at least one combination partner of biological affinity, attached to a solid phase.
    Type: Grant
    Filed: March 30, 2001
    Date of Patent: January 18, 2005
    Assignee: Dade Behring Marburg GmbH
    Inventors: Heinz-Jürgen Friesen, Gerd Grenner, Hans-Erwin Pauly, Helmut Kohl, Klaus Habenstein, Joseph Stärk
  • Sheet-like diagnostic device
    Patent number: RE37437
    Abstract: A solid diagnostic device for the quantitative determination of substances of biological affinity in biological fluids is described. A process is also described in which the biological fluid is brought into contact with a specific functional sector of the device, the fluid migrates through several functional sectors situated beside one another and containing suitable reagent components, and one or more substances of biological affinity are detected in such functional sectors which contain, for each substance to be detected, at least one combination partner of biological affinity, attached to a solid phase.
    Type: Grant
    Filed: October 18, 1995
    Date of Patent: November 6, 2001
    Assignee: Dade Behring Marburg, GmbH
    Inventors: Heinz-Jürgen Friesen, Gerd Grenner, Hans-Erwin Pauly, Helmut Kohl, Klaus Habenstein, Joseph Stärk