Patents by Inventor Heinz-Michael Hein
Heinz-Michael Hein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8940249Abstract: A system for the automated analysis of liquid samples having one or more processing units for reaction between the samples and one or more reagents to thereby obtain reaction products is disclosed. Disclosed also are a sample unit for supplying the samples to the one or more processing units; a reagent unit equipped with plural reagent vessels containing one or more reagents for mixing with the samples; a distribution unit for distributing fluids including the one or more reagents provided with plural distribution lines, at least some of which are connected to the reagent vessels and the one or more processing units; and at least one analytical unit for analyzing the samples based on the reaction products, in which the analytical unit may include at least one detector for detecting the reaction products.Type: GrantFiled: August 5, 2010Date of Patent: January 27, 2015Assignee: Roche Diagnostics Operations, Inc.Inventors: Rainer D. Jaeggi, Oliver Gutmann, Michael Glauser, Heinz-Michael Hein, Edwin Oosterbroek, Michael Andreas Heinrich
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Patent number: 8821413Abstract: A system is provided for withdrawing small amounts of body fluid from an animal or human. The system includes a holder and a disposable lancing unit attached to the holder. The lancing unit also includes an open capillary channel for transporting the body fluid and piercing the skin.Type: GrantFiled: February 20, 2013Date of Patent: September 2, 2014Assignee: Roche Diagnostics Operations, Inc.Inventors: Carlo Effenhauser, Heinz-Michael Hein, Karl-Heinz Koelker, Frank Deck
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Patent number: 8636675Abstract: The present invention provides a method and a device for piercing a body part and determining whether a sufficient volume of blood has been withdrawn. A lancing element is rapidly inserted into a body part in a forward phase and retracted quickly to a lesser puncturing depth. Subsequently, the lancing element is retracted slower than during the first retraction movement and the distance retracted during the second retraction is shorter than the first retraction movement. During the second retraction movement, body fluid is collected in a collection phase by a capillary structure of the lancing element. Contact between the lancing element and the body fluid is detected after the forward phase at the beginning and the end of a waiting period.Type: GrantFiled: October 8, 2010Date of Patent: January 28, 2014Assignee: Roche Diagnostics Operations, Inc.Inventors: Heinz-Michael Hein, Reto Abt, Stephan Korner, Irio Giuseppe Calasso, Emad Sarofim, Patrick Griss, Rainer Jaeggi
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Patent number: 8501000Abstract: The present invention includes a container and a method of separating one or more components of interest bound to magnetic particles using centrifugal forces.Type: GrantFiled: October 10, 2012Date of Patent: August 6, 2013Assignee: Roche Molecular Systems, Inc.Inventors: Heinz-Michael Hein, Emad Sarofim, Lotar Schenk, Hans-Peter Wahl
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Patent number: 8394117Abstract: The invention relates to a method for creating a puncture wound for obtaining a sample of a body fluid from a body part in which a skin opening is created at a puncture site in the epidermis in a skin-opening step. Then, in a sample collection step a sample collection puncture is executed by using a puncture element with which the skin opening is deepened with the puncture element, thereby creating a puncture wound for obtaining the sample. The invention also relates to a handheld apparatus for implementing this method.Type: GrantFiled: March 2, 2008Date of Patent: March 12, 2013Assignee: Roche Diagnostics Operations, Inc.Inventors: Heinz-Michael Hein, Irio Calasso, Hans List
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Patent number: 8388552Abstract: A system is provided for withdrawing small amounts of body fluid from an animal or human. The system includes a holder and a disposable lancing unit attached to the holder. The lancing unit also includes an open capillary channel for transporting the body fluid and piercing the skin.Type: GrantFiled: June 30, 2011Date of Patent: March 5, 2013Assignee: Roche Diagnostics Operations, Inc.Inventors: Carlo Effenhauser, Heinz-Michael Hein, Karl-Heinz Koelker, Frank Deck
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Patent number: 8313652Abstract: The present invention includes a container and a method of separating one or more components of interest bound to magnetic particles using centrifugal forces.Type: GrantFiled: November 12, 2009Date of Patent: November 20, 2012Assignee: Roche Molecular Systems, Inc.Inventors: Heinz Michael Hein, Emad Sarofim, Lotar Schenk, Hans-Peter Wahl
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Publication number: 20120156113Abstract: A process for automatically washing fluid lines of a fluidic system for combining liquid samples with one or more reagents, the system being provided with at least one main line connected to one or more reagent lines for feeding reagents, each of which being connectable to a reagent container by a fluidic connector, at least one sample intake for intaking samples and at least one pressure actuator for generating a positive or negative pressure in the fluid lines.Type: ApplicationFiled: December 15, 2011Publication date: June 21, 2012Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.Inventors: Michael Glauser, Heinz Michael Hein, Rainer D. Jaeggi
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Publication number: 20110257559Abstract: A system is provided for withdrawing small amounts of body fluid from an animal or human. The system includes a holder and a disposable lancing unit attached to the holder. The lancing unit also includes an open capillary channel for transporting the body fluid and piercing the skin.Type: ApplicationFiled: June 30, 2011Publication date: October 20, 2011Inventors: Carlo Effenhauser, Heinz-Michael Hein, Harl-Heinz Koelker, Frank Deck
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Patent number: 7993284Abstract: A system is provided for withdrawing small amounts of body fluid from an animal or human. The system includes a holder and a disposable lancing unit attached to the holder. The lancing unit also includes an open capillary channel for transporting the body fluid and piercing the skin.Type: GrantFiled: September 20, 2007Date of Patent: August 9, 2011Assignee: Roche Diagnostics Operations, Inc.Inventors: Carlo Effenhauser, Heinz-Michael Hein, Karl-Heinz Koelker, Frank Deck
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Publication number: 20110189052Abstract: A system for the automated analysis of liquid samples having one or more processing units for reaction between the samples and one or more reagents to thereby obtain reaction products is disclosed. Disclosed also are a sample unit for supplying the samples to the one or more processing units; a reagent unit equipped with plural reagent vessels containing one or more reagents for mixing with the samples; a distribution unit for distributing fluids including the one or more reagents provided with plural distribution lines, at least some of which are connected to the reagent vessels and the one or more processing units; and at least one analytical unit for analyzing the samples based on the reaction products, in which the analytical unit may include at least one detector for detecting the reaction products.Type: ApplicationFiled: August 5, 2010Publication date: August 4, 2011Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.Inventors: Rainer D. Jaeggi, Oliver Gutmann, Michael Glauser, Heinz-Michael Hein, Edwin Oosterbroek, Michael Andreas Heinrich
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Publication number: 20110028862Abstract: The present invention provides a method and a device for piercing a body part and determining whether a sufficient volume of blood has been withdrawn. A lancing element is rapidly inserted into a body part in a forward phase and retracted quickly to a lesser puncturing depth. Subsequently, the lancing element is retracted slower than during the first retraction movement and the distance retracted during the second retraction is shorter than the first retraction movement. During the second retraction movement, body fluid is collected in a collection phase by a capillary structure of the lancing element. Contact between the lancing element and the body fluid is detected after the forward phase at the beginning and the end of a waiting period.Type: ApplicationFiled: October 8, 2010Publication date: February 3, 2011Inventors: Heinz-Michael Hein, Reto Abt, Stephan Korner, Irio Giuseppe Calasso, Emad Sarofim, Patrick Griss, Rainer Jaeggi
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Patent number: 7833172Abstract: The present invention provides a method and a device for piercing a body part and determining whether a sufficient volume of blood has been withdrawn. A lancing element is rapidly inserted into a body part in a forward phase and retracted quickly to a lesser puncturing depth. Subsequently, the lancing element is retracted slower than during the first retraction movement and the distance retracted during the second retraction is shorter than the first retraction movement. During the second retraction movement, body fluid is collected in a collection phase by a capillary structure of the lancing element. Contact between the lancing element and the body fluid is detected after the forward phase at the beginning and the end of a waiting period.Type: GrantFiled: October 7, 2007Date of Patent: November 16, 2010Assignee: Roche Diagnostics Operations, Inc.Inventors: Heinz-Michael Hein, Reto Abt, Stephan Korner, Irio Giuseppe Calasso, Emad Sarofim, Patrick Griss, Rainer Jaeggi
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Publication number: 20100163493Abstract: The present invention includes a container and a method of separating one or more components of interest bound to magnetic particles using centrifugal forces.Type: ApplicationFiled: November 12, 2009Publication date: July 1, 2010Applicant: Roche Molecular Systems, Inc.Inventors: Heinz Michael Hein, Emad Sarofim, Lotar Schenk, Hans-Peter Wahl
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Patent number: 7586612Abstract: On an analytical device for photometric analysis of chemistry and/or fluid samples comprising a rotatable disk-like body, a plurality of receptacles for fluid samples and optics for guiding light beams through the receptacles are arranged. At least part of the optics are designed and/or arranged such that at least part of the light beams is deflected and guided through the receptacles at an angle to the radially outward direction on the disk-like body which means at an angle to the radius, connecting the respective optics with the rotation axis of the disk-like body.Type: GrantFiled: August 8, 2006Date of Patent: September 8, 2009Assignee: Roche Diagnostics Operations, Inc.Inventors: Goran Savatic, Patrick Griss, Heinz-Michael Hein, Rainer Jaeggi
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Patent number: 7565249Abstract: A method is proposed for the selective determination of a light transport parameter which is characteristic for the light scattering in a biological matrix (5), in particular for the purpose of the non-invasive determination of the glucose concentration in the biological matrix. The method comprises providing a plurality of detection measurements, in which light is irradiated as primary light into the biological matrix and measuring an intensity value of secondary light emerging at a plurality detection sites, located in different measuring distances from the irradiation site. In an evaluation step, the light transport parameter is derived, by means of an evaluation algorithm, from the measured intensity values.Type: GrantFiled: February 23, 2002Date of Patent: July 21, 2009Assignee: Roche Diagnostics Operations, Inc.Inventors: Uwe Kraemer, Heinz-Michael Hein, Dietmar Volz
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Publication number: 20080208079Abstract: The invention relates to a method for creating a puncture wound for obtaining a sample of a body fluid from a body part in which a skin opening is created at a puncture site in the epidermis in a skin-opening step. Then, in a sample collection step a sample collection puncture is executed by using a puncture element with which the skin opening is deepened with the puncture element, thereby creating a puncture wound for obtaining the sample. The invention also relates to a handheld apparatus for implementing this method.Type: ApplicationFiled: March 2, 2008Publication date: August 28, 2008Inventors: Heinz-Michael Hein, Irio Calasso, Hans List
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Publication number: 20080108910Abstract: The present invention provides a method and a device for piercing a body part and determining whether a sufficient volume of blood has been withdrawn. A lancing element is rapidly inserted into a body part in a forward phase and retracted quickly to a lesser puncturing depth. Subsequently, the lancing element is retracted slower than during the first retraction movement and the distance retracted during the second retraction is shorter than the first retraction movement. During the second retraction movement, body fluid is collected in a collection phase by a capillary structure of the lancing element. Contact between the lancing element and the body fluid is detected after the forward phase at the beginning and the end of a waiting period.Type: ApplicationFiled: October 7, 2007Publication date: May 8, 2008Inventors: Heinz-Michael Hein, Reto Abt, Stephan Korner, Irio Calasso, Emad Sarofim, Patrick Griss, Rainer Jaeggi
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Patent number: 7369952Abstract: The invention relates to analysis methods for diagnosing diseases on human and animal samples. Said invention also relates to an evaluation method for diagnosing the individual stages of a disease in such a way that it is possible to display the progression thereof. Said invention also makes it possible to identify diseases in an early manner and to carry out therapeutic controls. The inventive method consists in carrying out actually known multivariable evaluation methods for classifying samples. Nevertheless, the invention is characterised in that no sample is allocated to a certain class, but it is classified in a data record based on the interpolation between different classes.Type: GrantFiled: April 6, 2004Date of Patent: May 6, 2008Assignee: Roche Diagnostics Operations, Inc.Inventors: Wolfgang Petrich, Gerhard Werner, Heinz-Michael Hein, Hans-Juergen Kuhr
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Publication number: 20080009767Abstract: A system is provided for withdrawing small amounts of body fluid from an animal or human. The system includes a holder and a disposable lancing unit attached to the holder. The lancing unit also includes an open capillary channel for transporting the body fluid and piercing the skin.Type: ApplicationFiled: September 20, 2007Publication date: January 10, 2008Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.Inventors: Carlo Effenhauser, Heinz-Michael Hein, Karl-Heinz Koelker, Frank Deck