Patents by Inventor Heinz-Michael Hein

Heinz-Michael Hein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8940249
    Abstract: A system for the automated analysis of liquid samples having one or more processing units for reaction between the samples and one or more reagents to thereby obtain reaction products is disclosed. Disclosed also are a sample unit for supplying the samples to the one or more processing units; a reagent unit equipped with plural reagent vessels containing one or more reagents for mixing with the samples; a distribution unit for distributing fluids including the one or more reagents provided with plural distribution lines, at least some of which are connected to the reagent vessels and the one or more processing units; and at least one analytical unit for analyzing the samples based on the reaction products, in which the analytical unit may include at least one detector for detecting the reaction products.
    Type: Grant
    Filed: August 5, 2010
    Date of Patent: January 27, 2015
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Rainer D. Jaeggi, Oliver Gutmann, Michael Glauser, Heinz-Michael Hein, Edwin Oosterbroek, Michael Andreas Heinrich
  • Patent number: 8821413
    Abstract: A system is provided for withdrawing small amounts of body fluid from an animal or human. The system includes a holder and a disposable lancing unit attached to the holder. The lancing unit also includes an open capillary channel for transporting the body fluid and piercing the skin.
    Type: Grant
    Filed: February 20, 2013
    Date of Patent: September 2, 2014
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Carlo Effenhauser, Heinz-Michael Hein, Karl-Heinz Koelker, Frank Deck
  • Patent number: 8636675
    Abstract: The present invention provides a method and a device for piercing a body part and determining whether a sufficient volume of blood has been withdrawn. A lancing element is rapidly inserted into a body part in a forward phase and retracted quickly to a lesser puncturing depth. Subsequently, the lancing element is retracted slower than during the first retraction movement and the distance retracted during the second retraction is shorter than the first retraction movement. During the second retraction movement, body fluid is collected in a collection phase by a capillary structure of the lancing element. Contact between the lancing element and the body fluid is detected after the forward phase at the beginning and the end of a waiting period.
    Type: Grant
    Filed: October 8, 2010
    Date of Patent: January 28, 2014
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Heinz-Michael Hein, Reto Abt, Stephan Korner, Irio Giuseppe Calasso, Emad Sarofim, Patrick Griss, Rainer Jaeggi
  • Patent number: 8501000
    Abstract: The present invention includes a container and a method of separating one or more components of interest bound to magnetic particles using centrifugal forces.
    Type: Grant
    Filed: October 10, 2012
    Date of Patent: August 6, 2013
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Heinz-Michael Hein, Emad Sarofim, Lotar Schenk, Hans-Peter Wahl
  • Patent number: 8394117
    Abstract: The invention relates to a method for creating a puncture wound for obtaining a sample of a body fluid from a body part in which a skin opening is created at a puncture site in the epidermis in a skin-opening step. Then, in a sample collection step a sample collection puncture is executed by using a puncture element with which the skin opening is deepened with the puncture element, thereby creating a puncture wound for obtaining the sample. The invention also relates to a handheld apparatus for implementing this method.
    Type: Grant
    Filed: March 2, 2008
    Date of Patent: March 12, 2013
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Heinz-Michael Hein, Irio Calasso, Hans List
  • Patent number: 8388552
    Abstract: A system is provided for withdrawing small amounts of body fluid from an animal or human. The system includes a holder and a disposable lancing unit attached to the holder. The lancing unit also includes an open capillary channel for transporting the body fluid and piercing the skin.
    Type: Grant
    Filed: June 30, 2011
    Date of Patent: March 5, 2013
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Carlo Effenhauser, Heinz-Michael Hein, Karl-Heinz Koelker, Frank Deck
  • Patent number: 8313652
    Abstract: The present invention includes a container and a method of separating one or more components of interest bound to magnetic particles using centrifugal forces.
    Type: Grant
    Filed: November 12, 2009
    Date of Patent: November 20, 2012
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Heinz Michael Hein, Emad Sarofim, Lotar Schenk, Hans-Peter Wahl
  • Publication number: 20120156113
    Abstract: A process for automatically washing fluid lines of a fluidic system for combining liquid samples with one or more reagents, the system being provided with at least one main line connected to one or more reagent lines for feeding reagents, each of which being connectable to a reagent container by a fluidic connector, at least one sample intake for intaking samples and at least one pressure actuator for generating a positive or negative pressure in the fluid lines.
    Type: Application
    Filed: December 15, 2011
    Publication date: June 21, 2012
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Michael Glauser, Heinz Michael Hein, Rainer D. Jaeggi
  • Publication number: 20110257559
    Abstract: A system is provided for withdrawing small amounts of body fluid from an animal or human. The system includes a holder and a disposable lancing unit attached to the holder. The lancing unit also includes an open capillary channel for transporting the body fluid and piercing the skin.
    Type: Application
    Filed: June 30, 2011
    Publication date: October 20, 2011
    Inventors: Carlo Effenhauser, Heinz-Michael Hein, Harl-Heinz Koelker, Frank Deck
  • Patent number: 7993284
    Abstract: A system is provided for withdrawing small amounts of body fluid from an animal or human. The system includes a holder and a disposable lancing unit attached to the holder. The lancing unit also includes an open capillary channel for transporting the body fluid and piercing the skin.
    Type: Grant
    Filed: September 20, 2007
    Date of Patent: August 9, 2011
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Carlo Effenhauser, Heinz-Michael Hein, Karl-Heinz Koelker, Frank Deck
  • Publication number: 20110189052
    Abstract: A system for the automated analysis of liquid samples having one or more processing units for reaction between the samples and one or more reagents to thereby obtain reaction products is disclosed. Disclosed also are a sample unit for supplying the samples to the one or more processing units; a reagent unit equipped with plural reagent vessels containing one or more reagents for mixing with the samples; a distribution unit for distributing fluids including the one or more reagents provided with plural distribution lines, at least some of which are connected to the reagent vessels and the one or more processing units; and at least one analytical unit for analyzing the samples based on the reaction products, in which the analytical unit may include at least one detector for detecting the reaction products.
    Type: Application
    Filed: August 5, 2010
    Publication date: August 4, 2011
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Rainer D. Jaeggi, Oliver Gutmann, Michael Glauser, Heinz-Michael Hein, Edwin Oosterbroek, Michael Andreas Heinrich
  • Publication number: 20110028862
    Abstract: The present invention provides a method and a device for piercing a body part and determining whether a sufficient volume of blood has been withdrawn. A lancing element is rapidly inserted into a body part in a forward phase and retracted quickly to a lesser puncturing depth. Subsequently, the lancing element is retracted slower than during the first retraction movement and the distance retracted during the second retraction is shorter than the first retraction movement. During the second retraction movement, body fluid is collected in a collection phase by a capillary structure of the lancing element. Contact between the lancing element and the body fluid is detected after the forward phase at the beginning and the end of a waiting period.
    Type: Application
    Filed: October 8, 2010
    Publication date: February 3, 2011
    Inventors: Heinz-Michael Hein, Reto Abt, Stephan Korner, Irio Giuseppe Calasso, Emad Sarofim, Patrick Griss, Rainer Jaeggi
  • Patent number: 7833172
    Abstract: The present invention provides a method and a device for piercing a body part and determining whether a sufficient volume of blood has been withdrawn. A lancing element is rapidly inserted into a body part in a forward phase and retracted quickly to a lesser puncturing depth. Subsequently, the lancing element is retracted slower than during the first retraction movement and the distance retracted during the second retraction is shorter than the first retraction movement. During the second retraction movement, body fluid is collected in a collection phase by a capillary structure of the lancing element. Contact between the lancing element and the body fluid is detected after the forward phase at the beginning and the end of a waiting period.
    Type: Grant
    Filed: October 7, 2007
    Date of Patent: November 16, 2010
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Heinz-Michael Hein, Reto Abt, Stephan Korner, Irio Giuseppe Calasso, Emad Sarofim, Patrick Griss, Rainer Jaeggi
  • Publication number: 20100163493
    Abstract: The present invention includes a container and a method of separating one or more components of interest bound to magnetic particles using centrifugal forces.
    Type: Application
    Filed: November 12, 2009
    Publication date: July 1, 2010
    Applicant: Roche Molecular Systems, Inc.
    Inventors: Heinz Michael Hein, Emad Sarofim, Lotar Schenk, Hans-Peter Wahl
  • Patent number: 7586612
    Abstract: On an analytical device for photometric analysis of chemistry and/or fluid samples comprising a rotatable disk-like body, a plurality of receptacles for fluid samples and optics for guiding light beams through the receptacles are arranged. At least part of the optics are designed and/or arranged such that at least part of the light beams is deflected and guided through the receptacles at an angle to the radially outward direction on the disk-like body which means at an angle to the radius, connecting the respective optics with the rotation axis of the disk-like body.
    Type: Grant
    Filed: August 8, 2006
    Date of Patent: September 8, 2009
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Goran Savatic, Patrick Griss, Heinz-Michael Hein, Rainer Jaeggi
  • Patent number: 7565249
    Abstract: A method is proposed for the selective determination of a light transport parameter which is characteristic for the light scattering in a biological matrix (5), in particular for the purpose of the non-invasive determination of the glucose concentration in the biological matrix. The method comprises providing a plurality of detection measurements, in which light is irradiated as primary light into the biological matrix and measuring an intensity value of secondary light emerging at a plurality detection sites, located in different measuring distances from the irradiation site. In an evaluation step, the light transport parameter is derived, by means of an evaluation algorithm, from the measured intensity values.
    Type: Grant
    Filed: February 23, 2002
    Date of Patent: July 21, 2009
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Uwe Kraemer, Heinz-Michael Hein, Dietmar Volz
  • Publication number: 20080208079
    Abstract: The invention relates to a method for creating a puncture wound for obtaining a sample of a body fluid from a body part in which a skin opening is created at a puncture site in the epidermis in a skin-opening step. Then, in a sample collection step a sample collection puncture is executed by using a puncture element with which the skin opening is deepened with the puncture element, thereby creating a puncture wound for obtaining the sample. The invention also relates to a handheld apparatus for implementing this method.
    Type: Application
    Filed: March 2, 2008
    Publication date: August 28, 2008
    Inventors: Heinz-Michael Hein, Irio Calasso, Hans List
  • Publication number: 20080108910
    Abstract: The present invention provides a method and a device for piercing a body part and determining whether a sufficient volume of blood has been withdrawn. A lancing element is rapidly inserted into a body part in a forward phase and retracted quickly to a lesser puncturing depth. Subsequently, the lancing element is retracted slower than during the first retraction movement and the distance retracted during the second retraction is shorter than the first retraction movement. During the second retraction movement, body fluid is collected in a collection phase by a capillary structure of the lancing element. Contact between the lancing element and the body fluid is detected after the forward phase at the beginning and the end of a waiting period.
    Type: Application
    Filed: October 7, 2007
    Publication date: May 8, 2008
    Inventors: Heinz-Michael Hein, Reto Abt, Stephan Korner, Irio Calasso, Emad Sarofim, Patrick Griss, Rainer Jaeggi
  • Patent number: 7369952
    Abstract: The invention relates to analysis methods for diagnosing diseases on human and animal samples. Said invention also relates to an evaluation method for diagnosing the individual stages of a disease in such a way that it is possible to display the progression thereof. Said invention also makes it possible to identify diseases in an early manner and to carry out therapeutic controls. The inventive method consists in carrying out actually known multivariable evaluation methods for classifying samples. Nevertheless, the invention is characterised in that no sample is allocated to a certain class, but it is classified in a data record based on the interpolation between different classes.
    Type: Grant
    Filed: April 6, 2004
    Date of Patent: May 6, 2008
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Wolfgang Petrich, Gerhard Werner, Heinz-Michael Hein, Hans-Juergen Kuhr
  • Publication number: 20080009767
    Abstract: A system is provided for withdrawing small amounts of body fluid from an animal or human. The system includes a holder and a disposable lancing unit attached to the holder. The lancing unit also includes an open capillary channel for transporting the body fluid and piercing the skin.
    Type: Application
    Filed: September 20, 2007
    Publication date: January 10, 2008
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Carlo Effenhauser, Heinz-Michael Hein, Karl-Heinz Koelker, Frank Deck