Abstract: A method for transferring objects includes providing a medium in a reservoir, the medium containing objects; providing a substrate having an acceptor surface, the acceptor surface facing an opening of the reservoir; determining a first target focus point in the medium; and generating a first laser pulse or first laser pulse train focused onto the first target focus point. Pulse intensity of the first laser pulse or pulse train at the first target focus point and/or pulse duration of the first laser pulse or pulse train is/are chosen to generate a droplet of the medium ejected towards the acceptor surface. A center wavelength of the first laser pulse or pulse train is larger than 500 nm, larger than 650 nm, or between 0.9 ?m and 1.35 ?m. The first target focus point is determined relative to the position of at least one object of the objects.

Abstract: The present invention provides compounds of the general formula (I) or a pharmaceutically acceptable prodrugs, salts and/or solvates thereof, wherein LHS is selected from the group consisting of LHSa and LHSb And wherein, the asterisk (*) marks the point of attachment; These compounds exhibit antibacterial activity against Gram-negative and Gram-positive bacteria, especially S. aureus, E. coli, K. pneumoniae and A. baumannii. Pharmaceutical compositions containing these compounds, therapeutic uses thereof and methods for manufacturing the same are also provided.

Abstract: A method for transferring objects includes providing a medium in a reservoir, the medium containing objects; providing a substrate having an acceptor surface, the acceptor surface facing an opening of the reservoir; determining a first target focus point in the medium; and generating a first laser pulse or first laser pulse train focused onto the first target focus point. Pulse intensity of the first laser pulse or pulse train at the first target focus point and/or pulse duration of the first laser pulse or pulse train is/are chosen to generates a droplet of the medium ejected towards the acceptor surface. A center wavelength of the first laser pulse or pulse train is larger than 500 nm, larger than 650 nm, or between 0.9 ?m and 1.35 ?m. The first target focus point is determined relative to the position of at least one object of the objects.

Abstract: A method for evaluating signal curves on sensor devices includes acquiring a temporal signal curve with a sensor device. Time intervals are formed from this signal curve, and at least one upper actual interval value and at least one lower actual interval value are calculated for each interval. The interval values for each interval are then compared with intervals of stored templates having comparison interval values assigned thereto, wherein it is determined whether the interval lies between the actual interval values inside the interval for the comparison interval values, and thus whether a valid actuation signal is present.

Abstract: The present invention relates to formulations which comprise a plasticizer and articles made therefrom and/or coated therewith. More specifically the formulation comprises a plasticizer and a fungicidally effective amount of Fludioxonil and/or Difenoconazole. The formulations have particular application in the manufacture of plasticized articles and articles which have been coated with a fungicide containing plastisol.

Abstract: This invention relates to compounds of formula which inhibit Factor Xa or tryptase, to pharmaceutical compositions containing the compounds, and to the use of the compounds for the treatment of patients suffering from conditions which can be ameliorated by the administration of an inhibitor of Factor Xa or tryptase.

Abstract: The present invention relates to formulations which comprise a plasticizer and articles made therefrom and/or coated therewith. More specifically the formulation comprises a plasticizer and a fungicidally effective amount of Fludioxonil and/or Difenoconazole. The formulations have particular application in the manufacture of plasticized articles and articles which have been coated with a fungicide containing plastisol.

Abstract: In part, the present invention is directed to antibacterial compounds of formula (I) wherein A is a bicyclic heteroaryl ring or a tricyclic ring and R2 is an heterocyclic residue; L is a bond, or L is alkyl, alkenyl or cycloalkyl.

Abstract: Provided herein are novel and useful compounds having a tryptase inhibition activity, pharmaceutical compositions comprising such compounds, and methods treating subjects suffering from a condition, disease, or disorder that can be ameliorated by the administration of an inhibitor of tryptase, e.g., asthma and inflammatory diseases, to name only a few.

Abstract: Provided herein are novel and useful compounds having a tryptase inhibition activity, pharmaceutical compositions comprising such compounds, and methods treating subjects suffering from a condition, disease, or disorder that can be ameliorated by the administration of an inhibitor of tryptase, e.g., asthma and inflammatory diseases, to name only a few.

Abstract: The invention relates to a cross-linkable, halogen-free, flame-resistant plastic mixture which can especially be used, in a cross-linkable state, for coating cables. The inventive plastic mixture comprises the following plastic components: (a) 3 to 50 weight parts (phr) of at least one ethylene copolymer from the group comprising ethylene vinyl acetates, ethylene ethyl acrylates, ethylene methyl acrylates or ethylene butyl acrylates, (b) 30 to 96 weight parts (phr) of a high-density polyolefin, especially a HDPE (High Density Polyethylene) having a density of >0.94 g/cm3, and (c) 1 to 20 weight parts (phr) of a polyolefin which has been grafted with a derivative of an unsaturated carboxylic acid, especially HDPE-g carboxylic acid derivatives. Components (a) to (c) together produce a total of 100 weight parts (phr) of plastic. The mixture also comprises the following components: (d) 40 to 250 weight parts (phr) of a filling material, and (c) 0.1 to 15 weight parts (phr) of a stabilizer system.

Abstract: This invention relates to compounds of formula 1

Abstract: Provided herein are novel and useful compounds having a tryptase inhibition activity, pharmaceutical compositions comprising such compounds, and methods treating subjects suffering from a condition, disease, or disorder that can be ameliorated by the administration of an inhibitor of tryptase, e.g., asthma and inflammatory diseases, to name only a few.

Abstract: This invention relates to compounds of formula 1

Abstract: A device and method for defining a three-dimensional structure of an object having a submicrometer size splits a coherent electromagnetic radiation beam into two partial beams including a first partial beam and a second partial beam. The first partial beam is focused on the object. The first partial beam is reflected from or dispersed from the object to yield a first radiation directed toward a locus. The second partial beam is directed toward the locus. The first radiation and the second radiation form an electromagnetic combination in a region of the locus. Second phase values are established from the initial phase values via multiplication of the initial phase values by one or more predetermined values to provide information for generating a magnified image representative of the object.

Abstract: A method of treating a surface of a fiber, e.g. cellulosic fiber, with a finish in which the surface finish is applied as an aqueous emulsion stabilized at a first pH value and at the latest when applied to the fiber the emulsion is caused to destabilize by a change in the first pH value. The invention also relates to cellulosic fiber and threads thereof and to tampons made from cellulosic fiber.

Abstract: The invention relates to filaments and fibers of acrylonitrile polymers, which contain 10 to 30% by weight of carboxyl groups, their use and processes for their production. The filaments and fibers exhibit, in the dry state, tensile strengths of more than 10 cN/tex and knot strengths of more than 6 cN/tex and can be processed on customary machinery and are suitable for the production of shaped structures of high water retention. The polymeric raw materials required for the spinning are produced by hydrolysis of acrylonitrile polymers using aqueous dilute acids in a heterogeneous phase system.

Abstract: A cultivator for such crops as beets, maize, potatoes, etc., planted in rows. A machine frame can be mounted on the three-point hitch of a tractor. Several chopping tools mounted on it, can be detached from tool holders, and are rotated on vertical shafts. Force from a common drive mechanism is distributed to the shafts through a transmission. Each tool is rotated by one shaft and is mounted on a parallelogram. Each chopping tool (20) has one or more brushes that can be secured to the tool holder (18) and that have bristles of a flexible and resilient material and is shaped like an inverted flower pot. A stop (22) that rests against the ground at a level that can be adjusted in relation to the tool is accommodated in the inside (21) of the tool and can be detached from its center.

Abstract: A fiber or filament of a swellable polymer of high tensile strength is made by spinning a polymeric raw material which is produced by agitating a suspension of solid particles of an acrylonitrile polymer in dilute sulfuric acid having an acid concentration between 40 to 50 percent by weight until the polymer is hydrolyzed to an extent that it contains from 10 to 30 percent by weight of carboxyl groups such that sticking of individual particles of the polymer to one another is avoided.

Abstract: In the case of a method for sowing separate seeds in a furrow made by a ploughshare, the separate seeds run in a guide-device, are trapped in the vicinity of the ploughshare, are stored intermediately for a short time and are then released into the furrow. Upon being trapped, the individual seeds are stored intermediately spot-wise in relation to an axis corresponding to the direction of release and under a centering action. The individual seeds are accelerated, by a brief fluid-pulse in the direction of release, from the stationary intermediate storage position and are released into the furrow.