Patents by Inventor Heiyoung Park

Heiyoung Park has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of identifying inhibitors of sensor histidine kinases through rational drug design
    Patent number: 6162627
    Abstract: The present invention provides N-terminal truncated transmembrane sensor histidine kinases that retain their ability to be autophosphorylated and/or their related histidine kinase activity. The N-terminal truncated transmembrane sensor histidine kinases are useful for obtaining detailed three-dimensional structural data of the catalytic portion of the protein. The three-dimensional structural data is included as part of the invention. In addition, the present invention provides methodology for related structure based rational drug design using the three-dimensional data. Nucleotide and amino acid sequences of the N-terminal truncated transmembrane sensor histidine kinases are also provided.
    Type: Grant
    Filed: September 23, 1998
    Date of Patent: December 19, 2000
    Assignees: University of Medicine and Dentistry of New Jersey, Ontario Cancer Institute
    Inventors: Masayori Inouye, Heiyoung Park, Mitsuhiko Ikura
  • Methods of identifying inhibitors of sensor histidine kinases through rational drug design
    Patent number: 6077682
    Abstract: The present invention provides N-terminal truncated transmembrane sensor histidine kinases that retain their ability to be autophophorylated and/or their related histidine kinase activity. The N-terminal truncated transmembrane sensor histidine kinases are useful for obtaining detailed three-dimensional structural data of the catalytic portion of the protein. The three-dimensional structural data is included as part of the invention. In addition, the present invention provides methodology for related structure based rational drug design using the three-dimensional data. Nucleotide and amino acid sequences of the N-terminal truncated transmembrane sensor histidine kinases are also provided.
    Type: Grant
    Filed: March 19, 1998
    Date of Patent: June 20, 2000
    Assignees: University of Medicine and Dentistry of New Jersey, Ontario Cancer Institute
    Inventors: Masayori Inouye, Heiyoung Park, Mitsuhiko Ikura