Patents by Inventor Helen Cumberbatch

Helen Cumberbatch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • sGC stimulators
    Patent number: 11897887
    Abstract: The present disclosure relates to stimulators of soluble guanylate cyclase (sGC), pharmaceutically acceptable salts, pharmaceutical formulations comprising them as well as their phosphate ester prodrugs, and their uses alone or in combination with one or more additional agents, for treating various diseases, wherein an increase in the concentration of nitric oxide (NO) and/or an increase in the concentration of cyclic Guanosine Monophosphate (cGMP), or both, or the upregulation of the NO pathway is desirable. The compounds are of Formula I.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: February 13, 2024
    Assignee: Tisento Therapeutics Inc.
    Inventors: Glen Robert Rennie, Paul Allan Renhowe, Takashi Nakai, Ara Mermerian, Helen Cumberbatch
  • sGC STIMULATORS
    Publication number: 20200377508
    Abstract: The present disclosure relates to stimulators of soluble guanylate cyclase (sGC), pharmaceutically acceptable salts, pharmaceutical formulations comprising them as well as their phosphate ester prodrugs, and their uses alone or in combination with one or more additional agents, for treating various diseases, wherein an increase in the concentration of nitric oxide (NO) and/or an increase in the concentration of cyclic Guanosine Monophosphate (cGMP), or both, or the upregulation of the NO pathway is desirable. The compounds are of Formula I.
    Type: Application
    Filed: December 19, 2018
    Publication date: December 3, 2020
    Inventors: Glen Robert Rennie, Paul Allan Renhowe, Takashi Nakai, Ara Mermerian, Helen Cumberbatch