Patents by Inventor Helen Dooley

Helen Dooley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SHARK-DERIVED BINDING MOLECULES FOR SARS-COV-2 CORONAVIRUS AND USES THEREOF
    Publication number: 20230331823
    Abstract: Disclosed herein are shark-derived antibodies and binding molecules with high binding affinity for SARS-CoV-2 coronavirus and the use thereof. Some of the shark-derived antibodies and binding molecules also demonstrate cross-reactivity with and neutralization of other related sarbecoviruses. The complementarity determining region (CDR) sequences and binding characteristics for these antibodies and binding molecules are provided. Also disclosed are the use of these antibodies and binding molecules to detect SARS-CoV-2 coronavirus or other related sarbecoviruses or to prevent or treat SARS-CoV-2 coronavirus or other related sarbecovirus infections.
    Type: Application
    Filed: September 15, 2021
    Publication date: October 19, 2023
    Inventors: Michael Gordon JOYCE, Kayvon MODJARRAD, Helen DOOLEY, Agnes HAJDUCZKI, Wei-Hung CHEN
  • Antigen binding domains
    Patent number: 8865431
    Abstract: A process for the production of an antigen specific antigen binding domain using a transformed host containing an expressible DNA sequence encoding the antigen specific antigen binding domain, wherein the antigen specific antigen binding domain is derived from a variable region of the immunoglobulin isotype NAR found in fish.
    Type: Grant
    Filed: October 25, 2011
    Date of Patent: October 21, 2014
    Assignees: University of Maryland, Aberdeen University
    Inventors: Helen Dooley, Andrew Porter, Martin Flajnik
  • ANTIGEN BINDING DOMAINS
    Publication number: 20120064074
    Abstract: A process for the production of an antigen specific antigen binding domain using a transformed host containing an expressible DNA sequence encoding the antigen specific antigen binding domain, wherein the antigen specific antigen binding domain is derived from a variable region of the immunoglobulin isotype NAR found in fish.
    Type: Application
    Filed: October 25, 2011
    Publication date: March 15, 2012
    Applicants: ABERDEEN UNIVERSITY, UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Helen Dooley, Andrew Porter, Martin Flajnik
  • Antigen binding domains
    Publication number: 20050043519
    Abstract: A process for the production of an antigen specific antigen binding domain using a transformed host containing an expressible DNA sequence encoding the antigen specific antigen binding domain, wherein the antigen specific antigen binding domain is derived from a variable region of the immunoglobulin isotype NAR found in fish.
    Type: Application
    Filed: August 12, 2002
    Publication date: February 24, 2005
    Inventors: Helen Dooley, Andrew Porter, Martin Flajnik