Abstract: The present invention relates to medicine, particularly immunology and gastroenterology. Specifically, it relates to probiotic bacteria and extracts thereof for therapeutic use for the treatment of inflammatory disorders such as inflammatory bowel disease. Provided is a composition comprising as active ingredient Faecalibacterium prausnitzii strain HTF-F (DSM 26943) or an extract thereof comprising extracellular polymeric matrix (EPM), and an acceptable carrier, diluent or excipient. Also provided is an anti-inflammatory composition comprising EPM extracted from F. prausnitzii strain HTF-F, and a method for preparing the same.

Abstract: A fluid, filled, curable composition comprising an organic liquid which is polymerizable to form a solid polymer without the formation of any elimination products and from 20 to 70% by volume of alumina trihydrate filler characterized in that filler has a median particle size of between 5 and 30 microns, and preferably between 6 and 20 microns, and has an average aspect ratio of less than 2,5:1, preferably less than 2.0:1, and desirably less than 1.8:1.The composition when cured provides shaped articles having improved mechanical properties and when used as a dispersion of low viscosity reduces the tendency for the composition to show color variations through the thickness of the sheet as exhibited using alumina trihydrate fillers of high aspect ratio.