Patents by Inventor Helen Fitzsimons

Helen Fitzsimons has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel Glutamic Acid Decarboxylase (GAD) Chimera And Methods Of Use
    Publication number: 20120071546
    Abstract: The invention relates to a novel Glutamic Acid Decarboxylase (GAD). More specifically, novel DNA and protein sequences relating to GAD. Additionally, the invention discloses a novel composition and related methods for treating neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, epilepsy, and the like, using viral and non-viral delivery systems that deliver therapeutic agents to specific regions of the brain.
    Type: Application
    Filed: November 29, 2011
    Publication date: March 22, 2012
    Applicant: NEUROLOGIX, INC.
    Inventors: Helen Fitzsimons, Ross Bland
  • Glutamic acid decarboxylase (GAD) chimera and methods of use
    Patent number: 8071563
    Abstract: The invention relates to a novel Glutamic Acid Decarboxylase (GAD). More specifically, novel DNA and protein sequences relating to GAD. Additionally, the invention discloses a novel composition and related methods for treating neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, epilepsy, and the like, using viral and non-viral delivery systems that deliver therapeutic agents to specific regions of the brain. More specifically, using an adeno-associated viral vector to deliver a nucleotide sequence encoding a novel glutamic acid decarboxylase (GAD) to specific regions of the brain that are over stimulated or disinhibited in various diseases, including neurodegenerative diseases.
    Type: Grant
    Filed: March 24, 2009
    Date of Patent: December 6, 2011
    Assignee: Neurologix, Inc.
    Inventors: Helen Fitzsimons, Ross Bland
  • Novel Glutamic Acid Decarboxylase (GAD) Chimera And Methods Of Use
    Publication number: 20090233994
    Abstract: The invention relates to a novel Glutamic Acid Decarboxylase (GAD). More specifically, novel DNA and protein sequences relating to GAD. Additionally, the invention discloses a novel composition and related methods for treating neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, epilepsy, and the like, using viral and non-viral delivery systems that deliver therapeutic agents to specific regions of the brain.
    Type: Application
    Filed: March 24, 2009
    Publication date: September 17, 2009
    Applicant: NEUROLOGIX, INC.
    Inventors: Helen Fitzsimons, Ross Bland
  • Glutamic acid decarboxylase (GAD) chimera and methods of use
    Patent number: 7527785
    Abstract: The invention relates to a novel Glutamic Acid Decarboxylase (GAD). More specifically, novel DNA and protein sequences relating to GAD. Additionally, the invention discloses a novel composition and related methods for treating neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, epilepsy, and the like, using viral and non-viral delivery systems that deliver therapeutic agents to specific regions of the brain. More specifically, using an adeno-associated viral vector to deliver a nucleotide sequence encoding a novel glutamic acid decarboxylase (GAD) to specific regions of the brain that are over stimulated or disinhibited in various diseases, including neurodegenerative diseases.
    Type: Grant
    Filed: May 31, 2006
    Date of Patent: May 5, 2009
    Assignee: Neurologix, Inc.
    Inventors: Helen Fitzsimons, Ross Bland
  • Novel glutamic acid decarboxylase (GAD) chimera and methods of use
    Publication number: 20060275264
    Abstract: The invention relates to a novel Glutamic Acid Decarboxylase (GAD). More specifically, novel DNA and protein sequences relating to GAD. Additionally, the invention discloses a novel composition and related methods for treating neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, epilepsy, and the like, using viral and non-viral delivery systems that deliver therapeutic agents to specific regions of the brain.
    Type: Application
    Filed: May 31, 2006
    Publication date: December 7, 2006
    Inventors: Helen Fitzsimons, Ross Bland