Patents by Inventor Helen Katherine Smith

Helen Katherine Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted bis aryl and heteroaryl compounds as selective 5HTantagonists
    Patent number: 7625889
    Abstract: The present invention relates to a series of substituted bis aryl and heteroaryl compounds of formula (I): Wherein X, Y, Z, A, B, D, Ar, R1 and R2 are as defined herein. The compounds of this invention are selective 5HT2A antagonists, and are therefore, useful in treating a variety of diseases including but not limited to a wide variety of sleep disorders as disclosed and claimed herein.
    Type: Grant
    Filed: July 25, 2007
    Date of Patent: December 1, 2009
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Paul Robert Eastwood, Hazel Hunt, David Mark Fink, Helen Katherine Smith, Richard Simon Todd
  • Antimicrobial agents
    Patent number: 6716878
    Abstract: Compounds of formula (I) are antibacterial agents: wherein Z represents a radical of formula —N(OH)CH(═O) or of formula —C(═O)NH(OH), and R1-R4 are as defined in the specification. A method for the treatment of bacterial or protozoal infections in humans and non-human mammals, which comprises administering to a subject suffering such infection an antibacterially or antiprotozoally effective dose of a compound of formula (I) or a pharmaceutically or veterinarily acceptable salt, hydrate or solvate thereof.
    Type: Grant
    Filed: October 5, 2001
    Date of Patent: April 6, 2004
    Assignee: Vernalis (Oxford) Limited
    Inventors: Richard Simon Todd, Daniel Christopher Brookings, Helen Katherine Smith, Alison Jane Thompson, Raymond Paul Beckett