Patents by Inventor Helen Marie Kirke

Helen Marie Kirke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Analytical method for fab and fab? molecules
    Patent number: 9096887
    Abstract: A method of measuring acidic species generated by degradation of a Fab or Fab? component of a Fab-PEG or a Fab?-PEG is provided. The method involves: a) cleaving PEG and a linker from the Fab-PEG or Fab?-PEG with an enzyme; b) optionally separating the PEG and linker from the Fab or Fab? to provide isolated Fab or Fab?; and c) quantitatively analyzing acidic species associated with the cleaved Fab or Fab? and/or the cleaved PEG.
    Type: Grant
    Filed: May 12, 2014
    Date of Patent: August 4, 2015
    Assignee: UCB PHARMA, S.A.
    Inventors: Bryan John Smith, Helen Marie Kirke
  • ANALYTICAL METHOD FOR FAB AND FAB' MOLECULES
    Publication number: 20140242625
    Abstract: A method of measuring acidic species generated by degradation of a Fab or Fab? component of a Fab-PEG or a Fab?-PEG is provided. The method involves: a) cleaving PEG and a linker from the Fab-PEG or Fab?-PEG with an enzyme; b) optionally separating the PEG and linker from the Fab or Fab? to provide isolated Fab or Fab?; and c) quantitatively analyzing acidic species associated with the cleaved Fab or Fab? and/or the cleaved PEG.
    Type: Application
    Filed: May 12, 2014
    Publication date: August 28, 2014
    Applicant: UCB PHARMA, S.A.
    Inventors: BRYAN JOHN SMITH, HELEN MARIE KIRKE
  • Analytical method for FAB and FAB? molecules
    Patent number: 8722353
    Abstract: A method of measuring acidic species generated by degradation of a Fab or Fab? component of a Fab-PEG or a Fab?-PEG is provided. The method involves: a) cleaving PEG and a linker from the Fab-PEG or Fab?-PEG with an enzyme; b) optionally separating the PEG and linker from the Fab or Fab? to provide isolated Fab or Fab?; and c) quantitatively analyzing acidic species associated with the cleaved Fab or Fab? and/or the cleaved PEG.
    Type: Grant
    Filed: July 28, 2011
    Date of Patent: May 13, 2014
    Assignee: UCB Pharma, S.A.
    Inventors: Bryan John Smith, Helen Marie Kirke
  • ANALYTICAL METHOD FOR FAB AND FAB' MOLECULES
    Publication number: 20130183703
    Abstract: A method of measuring acidic species generated by degradation of a Fab or Fab? component of a Fab-PEG or a Fab?-PEG comprising the steps of: a) cleaving the PEG and linker from the Fab-PEG or Fab?-PEG with an enzyme; b) optionally separating the PEG and linker generated in step a) from the Fab or Fab?, to provide a Fab or Fab?; and c) quantitatively analyzing acidic species associated with the cleaved Fab or Fab? and/or the cleaved PEG.
    Type: Application
    Filed: July 28, 2011
    Publication date: July 18, 2013
    Applicant: UCB PHARMA, S.A.
    Inventors: Bryan John Smith, Helen Marie Kirke